Q9SX68
Gene name |
RPL18 (At1g48350, F11A17.10) |
Protein name |
50S ribosomal protein L18, chloroplastic |
Names |
CL18 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT1G48350 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9SX68
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9SX68-F1 | Predicted | AlphaFoldDB |
6 variants for Q9SX68
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH04904147 | 10 | V>L | No | 1000Genomes | |
| ENSVATH00087179 | 21 | G>R | No | 1000Genomes | |
| tmp_1_17867351_C_T | 28 | A>V | No | 1000Genomes | |
| tmp_1_17867395_T_C | 43 | S>P | No | 1000Genomes | |
| tmp_1_17867963_C_T | 119 | P>S | No | 1000Genomes | |
| tmp_1_17868154_C_T | 151 | P>L | No | 1000Genomes |
No associated diseases with Q9SX68
No regional properties for Q9SX68
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q9SX68 | |||
8 GO annotations of cellular component
| Name | Definition |
|---|---|
| chloroplast | A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma. |
| chloroplast envelope | The double lipid bilayer enclosing the chloroplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space. |
| chloroplast stroma | The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis. |
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| nucleolus | A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
| ribonucleoprotein complex | A macromolecular complex that contains both RNA and protein molecules. |
| ribosome | An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| 5S rRNA binding | Binding to a 5S ribosomal RNA, the smallest RNA constituent of a ribosome. |
| structural constituent of ribosome | The action of a molecule that contributes to the structural integrity of the ribosome. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| translation | The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome. |
5 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P51784 | USP11 | Ubiquitin carboxyl-terminal hydrolase 11 | Homo sapiens (Human) | PR |
| Q9Y2K6 | USP20 | Ubiquitin carboxyl-terminal hydrolase 20 | Homo sapiens (Human) | PR |
| Q8R5H1 | Usp15 | Ubiquitin carboxyl-terminal hydrolase 15 | Mus musculus (Mouse) | PR |
| Q8R5K2 | Usp33 | Ubiquitin carboxyl-terminal hydrolase 33 | Mus musculus (Mouse) | PR |
| F6Z5C0 | usp15 | Ubiquitin carboxyl-terminal hydrolase 15 | Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTSVSGCGSV | SLITNRSAFL | GNGLQHRAVF | LKPWSSSSLQ | SRSMVVEAKT | KTSSEDRIAR |
| 70 | 80 | 90 | 100 | 110 | 120 |
| HSRIRKKVNG | TTERPRLCVF | RSNKHLYVQV | IDDTKMHTLA | SASTKQKPIS | EEFDYTSGPT |
| 130 | 140 | 150 | 160 | ||
| IEVAKKVGEV | IAKSCLEKGI | TKVAFDRGGY | PYHGRIEALA | AAAREHGLQF |