Q9STR4

PR
Gene name
ACS7 (At4g26200, T25K17.10)
Protein name
1-aminocyclopropane-1-carboxylate synthase 7
Names
ACC synthase 7, S-adenosyl-L-methionine methylthioadenosine-lyase 7
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT4G26200
EC number
4.4.1.14: Carbon-sulfur lyases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-57 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

3 structures for Q9STR4

Entry ID Method Resolution Chain Position Source
7DLW X-ray 219 A A/B/C/D 1-447 PDB
7DLY X-ray 294 A A/B 1-447 PDB
AF-Q9STR4-F1 Predicted AlphaFoldDB

29 variants for Q9STR4

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH06778195 13 N>Y No 1000Genomes
tmp_4_13275349_A_G 15 N>D No 1000Genomes
tmp_4_13275365_G_A 20 R>Q No 1000Genomes
tmp_4_13275449_C_T 48 S>F No 1000Genomes
tmp_4_13275452_A_G 49 H>R No 1000Genomes
tmp_4_13275635_A_C 77 N>H No 1000Genomes
tmp_4_13275717_A_G 104 K>R No 1000Genomes
tmp_4_13275748_G_A 114 M>I No 1000Genomes
tmp_4_13275797_C_T 131 L>F No 1000Genomes
ENSVATH14297773 132 T>P No 1000Genomes
ENSVATH12236114 135 A>P No 1000Genomes
ENSVATH12236165 136 T>P No 1000Genomes
tmp_4_13275842_C_T 146 L>F No 1000Genomes
tmp_4_13276148_C_G 182 S>R No 1000Genomes
tmp_4_13276156_A_C 185 H>P No 1000Genomes
ENSVATH00539132 194 E>D No 1000Genomes
ENSVATH12236168 197 Y>H No 1000Genomes
tmp_4_13276312_G_A 237 R>H No 1000Genomes
ENSVATH06778198 263 E>D No 1000Genomes
tmp_4_13276412_C_A 270 D>E No 1000Genomes
tmp_4_13276488_A_G 296 T>A No 1000Genomes
ENSVATH14297787 296 T>I No 1000Genomes
ENSVATH12236170 324 M>I No 1000Genomes
tmp_4_13276590_T_A 330 S>T No 1000Genomes
ENSVATH12236171 330 S>W No 1000Genomes
ENSVATH12236172 335 T>M No 1000Genomes
tmp_4_13276737_T_A 379 F>I No 1000Genomes
tmp_4_13276803_A_C 401 N>H No 1000Genomes
ENSVATH02925661 401 N>K No 1000Genomes

No associated diseases with Q9STR4

2 regional properties for Q9STR4

Type Name Position InterPro Accession
binding_site Aminotransferases, class-I, pyridoxal-phosphate-binding site 282 - 295 IPR004838
domain Aminotransferase, class I/classII 55 - 437 IPR004839

Functions

Description
EC Number 4.4.1.14 Carbon-sulfur lyases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

4 GO annotations of molecular function

Name Definition
1-aminocyclopropane-1-carboxylate synthase activity Catalysis of the reaction: S-adenosyl-L-methionine(1+) = 1-aminocyclopropane-1-carboxylate + S-methyl-5'-thioadenosine + H(+).
identical protein binding Binding to an identical protein or proteins.
pyridoxal phosphate binding Binding to pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.
transaminase activity Catalysis of the transfer of an amino group to an acceptor, usually a 2-oxo acid.

3 GO annotations of biological process

Name Definition
cellular amino acid metabolic process The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups, as carried out by individual cells.
ethylene biosynthetic process The chemical reactions and pathways resulting in the formation of ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator.
fruit ripening An developmental maturation process that has as participant a fruit. Ripening causes changes in one or more characteristics of a fruit (color, aroma, flavor, texture, hardness, cell wall structure) and may make it more attractive to animals and aid in seed dispersal.

4 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P31531 ACS1 1-aminocyclopropane-1-carboxylate synthase Glycine max (Soybean) (Glycine hispida) PR
Q9SAR0 ACS6 1-aminocyclopropane-1-carboxylate synthase 6 Arabidopsis thaliana (Mouse-ear cress) PR
Q06402 ACS2 1-aminocyclopropane-1-carboxylate synthase 2 Arabidopsis thaliana (Mouse-ear cress) PR
P18485 ACS2 1-aminocyclopropane-1-carboxylate synthase 2 Solanum lycopersicum (Tomato) (Lycopersicon esculentum) PR
10 20 30 40 50 60
MGLPLMMERS SNNNNVELSR VAVSDTHGED SPYFAGWKAY DENPYDESHN PSGVIQMGLA
70 80 90 100 110 120
ENQVSFDLLE TYLEKKNPEG SMWGSKGAPG FRENALFQDY HGLKTFRQAM ASFMEQIRGG
130 140 150 160 170 180
KARFDPDRIV LTAGATAANE LLTFILADPN DALLVPTPYY PGFDRDLRWR TGVKIVPIHC
190 200 210 220 230 240
DSSNHFQITP EALESAYQTA RDANIRVRGV LITNPSNPLG ATVQKKVLED LLDFCVRKNI
250 260 270 280 290 300
HLVSDEIYSG SVFHASEFTS VAEIVENIDD VSVKERVHIV YSLSKDLGLP GFRVGTIYSY
310 320 330 340 350 360
NDNVVRTARR MSSFTLVSSQ TQHMLASMLS DEEFTEKYIR INRERLRRRY DTIVEGLKKA
370 380 390 400 410 420
GIECLKGNAG LFCWMNLGFL LEKKTKDGEL QLWDVILKEL NLNISPGSSC HCSEVGWFRV
430 440
CFANMSENTL EIALKRIHEF MDRRRRF