Q9SJ84

PR
Gene name
FIM4
Protein name
Fimbrin-4
Names
AtFIM4, Fimbrin4
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT2G04750
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-140 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9SJ84

Entry ID Method Resolution Chain Position Source
AF-Q9SJ84-F1 Predicted AlphaFoldDB

127 variants for Q9SJ84

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_2_1662742_T_C 3 S>G No 1000Genomes
tmp_2_1662732_C_T 6 G>D No 1000Genomes
ENSVATH11119648 7 V>F No 1000Genomes
ENSVATH13967939 8 L>F No 1000Genomes
tmp_2_1662580_G_T,GTCA 33 T>K No 1000Genomes
ENSVATH05254102 38 G>C No 1000Genomes
ENSVATH05254101 40 V>I No 1000Genomes
ENSVATH05254100 50 A>S No 1000Genomes
tmp_2_1662527_T_G 51 K>Q No 1000Genomes
tmp_2_1662520_T_G 53 K>T No 1000Genomes
ENSVATH11119544 57 G>S No 1000Genomes
tmp_2_1662506_T_C 58 K>E No 1000Genomes
tmp_2_1662491_C_T 63 E>K No 1000Genomes
tmp_2_1662475_A_T 68 L>* No 1000Genomes
tmp_2_1662457_T_C 74 N>S No 1000Genomes
ENSVATH11119543 76 A>T No 1000Genomes
tmp_2_1662444_T_G 78 E>D No 1000Genomes
ENSVATH00207096 78 E>K No 1000Genomes
tmp_2_1662443_C_T 79 V>I No 1000Genomes
tmp_2_1662333_C_T 87 A>T No 1000Genomes
tmp_2_1662326_A_G 89 L>S No 1000Genomes
ENSVATH05254086 90 S>N No 1000Genomes
tmp_2_1662317_T_A 92 Q>L No 1000Genomes
ENSVATH05254083 115 N>I No 1000Genomes
ENSVATH05254081 132 D>E No 1000Genomes
ENSVATH05254080 133 E>V No 1000Genomes
ENSVATH11119535 134 P>S No 1000Genomes
ENSVATH11119535 134 P>T No 1000Genomes
ENSVATH11119334 135 N>D No 1000Genomes
ENSVATH13967937 139 Y>S No 1000Genomes
ENSVATH05254078 144 P>H No 1000Genomes
ENSVATH01645406 148 A>T No 1000Genomes
ENSVATH01645405 150 F>Y No 1000Genomes
tmp_2_1662120_G_C 158 L>V No 1000Genomes
ENSVATH05254074 166 A>T No 1000Genomes
tmp_2_1661993_C_A 169 G>W No 1000Genomes
tmp_2_1661981_C_T 173 E>K No 1000Genomes
tmp_2_1661975_C_T 175 A>T No 1000Genomes
ENSVATH11119332 175 A>V No 1000Genomes
tmp_2_1661963_T_C 179 K>E No 1000Genomes
tmp_2_1661938_C_T 187 R>K No 1000Genomes
ENSVATH00207093 198 A>G No 1000Genomes
tmp_2_1661890_C_A 203 C>F No 1000Genomes
ENSVATH11119331 204 T>I No 1000Genomes
tmp_2_1661885_C_T 205 V>I No 1000Genomes
tmp_2_1661759_A_C 226 F>C No 1000Genomes
tmp_2_1661672_G_C 232 Q>E No 1000Genomes
tmp_2_1661671_T_A 232 Q>L No 1000Genomes
ENSVATH05254062 242 T>I No 1000Genomes
tmp_2_1661610_G_T 252 N>K No 1000Genomes
ENSVATH11119326 255 V>A No 1000Genomes
tmp_2_1661508_A_T 259 M>K No 1000Genomes
ENSVATH11118894 289 S>Y No 1000Genomes
ENSVATH11118893 292 K>E No 1000Genomes
tmp_2_1661299_T_G 302 N>H No 1000Genomes
ENSVATH01645389 305 A>S No 1000Genomes
ENSVATH01645388 311 N>H No 1000Genomes
tmp_2_1661260_C_T 315 E>K No 1000Genomes
tmp_2_1661251_C_A 318 D>Y No 1000Genomes
ENSVATH11118889 323 A>T No 1000Genomes
tmp_2_1661235_G_A 323 A>V No 1000Genomes
ENSVATH05254053 328 E>K No 1000Genomes
tmp_2_1661187_A_G 339 L>P No 1000Genomes
ENSVATH11118887 349 A>V No 1000Genomes
tmp_2_1661154_T_G 350 N>T No 1000Genomes
ENSVATH11118886 351 L>I No 1000Genomes
ENSVATH05254052 357 A>S No 1000Genomes
tmp_2_1661118_T_C 362 H>R No 1000Genomes
ENSVATH00207087 364 N>I No 1000Genomes
ENSVATH11118634 365 G>R No 1000Genomes
tmp_2_1661012_G_T 371 P>T No 1000Genomes
ENSVATH01645378 380 M>R No 1000Genomes
ENSVATH05254038 383 E>K No 1000Genomes
ENSVATH11118632 385 E>V No 1000Genomes
ENSVATH05254037 387 T>N No 1000Genomes
tmp_2_1660916_C_T 403 A>T No 1000Genomes
tmp_2_1660769_G_C 425 D>E No 1000Genomes
tmp_2_1660747_T_A 433 N>Y No 1000Genomes
ENSVATH11118625 437 A>E No 1000Genomes
ENSVATH11118504 444 M>I No 1000Genomes
ENSVATH01645362 461 E>D No 1000Genomes
ENSVATH05254026 462 L>F No 1000Genomes
ENSVATH01645361 463 N>H No 1000Genomes
ENSVATH05254024 479 K>R No 1000Genomes
tmp_2_1660599_A_C 482 L>R No 1000Genomes
tmp_2_1660497_T_C 490 M>V No 1000Genomes
tmp_2_1660493_C_G 491 R>T No 1000Genomes
tmp_2_1660484_A_G 494 M>T No 1000Genomes
ENSVATH11118495 496 Q>K No 1000Genomes
ENSVATH13967936 502 R>K No 1000Genomes
ENSVATH05254021 505 C>F No 1000Genomes
ENSVATH00207082 505 C>W No 1000Genomes
tmp_2_1660445_C_T 507 G>D No 1000Genomes
tmp_2_1660436_A_G 510 I>T No 1000Genomes
ENSVATH11118304 512 E>V No 1000Genomes
tmp_2_1660409_G_T 519 A>E No 1000Genomes
ENSVATH05254018 521 R>K No 1000Genomes
tmp_2_1660398_C_T 523 V>I No 1000Genomes
ENSVATH00207081 526 S>T No 1000Genomes
ENSVATH05254017 528 R>Q No 1000Genomes
ENSVATH13967935 530 S>T No 1000Genomes
tmp_2_1660256_C_T 543 G>E No 1000Genomes
ENSVATH00207080 551 S>R No 1000Genomes
ENSVATH11118301 567 E>* No 1000Genomes
ENSVATH11118300 567 E>D No 1000Genomes
ENSVATH01645349 569 Q>E No 1000Genomes
tmp_2_1660089_T_G 569 Q>H No 1000Genomes
ENSVATH01645349 569 Q>K No 1000Genomes
tmp_2_1660080_C_A 572 K>N No 1000Genomes
ENSVATH11118298 572 K>R No 1000Genomes
tmp_2_1660056_T_C 580 I>M No 1000Genomes
ENSVATH11118297 594 P>S No 1000Genomes
ENSVATH01645343 603 R>K No 1000Genomes
ENSVATH05254006 610 A>T No 1000Genomes
ENSVATH05254005 617 L>F No 1000Genomes
ENSVATH11118229 626 T>A No 1000Genomes
tmp_2_1659842_CAG_TAG,C 627 V>I No 1000Genomes
tmp_2_1659824_C_T 633 V>I No 1000Genomes
ENSVATH01645341 635 S>A No 1000Genomes
ENSVATH01645341 635 S>T No 1000Genomes
ENSVATH05254001 638 E>* No 1000Genomes
tmp_2_1659799_G_A 641 S>F No 1000Genomes
ENSVATH05254000 644 S>L No 1000Genomes
tmp_2_1659785_C_A 646 D>Y No 1000Genomes
ENSVATH07765543 647 D>N No 1000Genomes
ENSVATH05253999 648 G>R No 1000Genomes
ENSVATH11118108 653 V>Y No 1000Genomes

No associated diseases with Q9SJ84

No regional properties for Q9SJ84

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q9SJ84

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm, cytoskeleton
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
actin filament A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane.
actin filament bundle An assembly of actin filaments that are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness.
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
actin filament binding Binding to an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits.

2 GO annotations of biological process

Name Definition
actin filament bundle assembly The assembly of actin filament bundles; actin filaments are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness.
actin filament network formation The assembly of a network of actin filaments; actin filaments on different axes and with differing orientations are crosslinked together to form a mesh of filaments.

4 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P13797 PLS3 Plastin-3 Homo sapiens (Human) PR
Q9FJ70 FIM3 Fimbrin-3 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FKI0 FIM5 Fimbrin-5 Arabidopsis thaliana (Mouse-ear cress) PR
Q7G188 FIM1 Fimbrin-1 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MSSYVGVLVS DPWLQSQFTQ VELRTLKSKF YSTKTRFGRV TVKHLPPVFA KLKYFNGKFD
70 80 90 100 110 120
ENEIKTILDE SYPNRAKEVE FETFLRAFLS VQSRGSKGAS SFLKTSTTTF HHSINESEKA
130 140 150 160 170 180
SYVSHINSYL KDEPNLKSYL PINPTTNALF DLVKDGVLLC KLINIAVPGT IDERAINTKK
190 200 210 220 230 240
ELNPWERTEN LSLCLNSAKA IGCTVVNIGT QDIAEGTPHL VLGLIFQIIK IQLLADLNLK
250 260 270 280 290 300
KTPQLVELVE ENQDVEELMG LAPEKLLLKW MNFHLKKAGY EKQVTNFSSD VKDGEAYAYL
310 320 330 340 350 360
LNALAPEHST NVTLEIKDPS ERATKVLEQA EKLDCKRFLS PKDIVEGSAN LNLAFVAQLF
370 380 390 400 410 420
HHRNGLSDES PKVPISVAEM VTEDEETSRE ERCFRHWMNS LGAVTYVDNV FEDVRNGWVL
430 440 450 460 470 480
LEVLDKVSPG SVNWKHANKP PIKMPFKKVE NCNQVIKIGK ELNFSLVNVA GHDIMQGNKK
490 500 510 520 530 540
LLLAFLWQLM RYTMLQILNN LRSHCQGKDI TEADILNWAN RKVKKSGRTS QAVSFKDKNL
550 560 570 580 590 600
ANGIFFLELL SAVEPRVVNW SLVSKGETQE EKNLNATYII SVARKLGCSI FLLPEDILEV
610 620 630 640 650
NQRMMLILAA SIMNWSLQQQ SDTESTVSDD TDVSSVTEEI SNLSTDDGSS DV