Q9FJ70
Gene name |
FIM3 |
Protein name |
Fimbrin-3 |
Names |
AtFIM3, Fimbrin3 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT5G55400 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9FJ70
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9FJ70-F1 | Predicted | AlphaFoldDB |
41 variants for Q9FJ70
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_5_22458940_A_G | 4 | F>S | No | 1000Genomes | |
| tmp_5_22458901_T_G | 17 | Q>P | No | 1000Genomes | |
| tmp_5_22458878_T_G | 25 | S>R | No | 1000Genomes | |
| tmp_5_22458752_T_G | 39 | K>Q | No | 1000Genomes | |
| ENSVATH03434185 | 43 | E>K | No | 1000Genomes | |
| ENSVATH03434184 | 78 | D>A | No | 1000Genomes | |
| ENSVATH07425496 | 82 | D>E | No | 1000Genomes | |
| ENSVATH07425493 | 132 | L>F | No | 1000Genomes | |
| ENSVATH14633733 | 200 | T>M | No | 1000Genomes | |
| tmp_5_22458019_T_A | 219 | Q>L | No | 1000Genomes | |
| ENSVATH12782894 | 243 | A>T | No | 1000Genomes | |
| tmp_5_22457738_C_T | 254 | V>I | No | 1000Genomes | |
| tmp_5_22457721_G_T | 259 | D>E | No | 1000Genomes | |
| ENSVATH07425488 | 260 | N>D | No | 1000Genomes | |
| ENSVATH07425486 | 289 | K>N | No | 1000Genomes | |
| tmp_5_22457531_T_A | 294 | N>I | No | 1000Genomes | |
| ENSVATH14633732 | 316 | H>Y | No | 1000Genomes | |
| ENSVATH07425482 | 322 | L>P | No | 1000Genomes | |
| ENSVATH00735662 | 341 | M>I | No | 1000Genomes | |
| ENSVATH07425480 | 355 | G>A | No | 1000Genomes | |
| ENSVATH07425479 | 378 | G>C | No | 1000Genomes | |
| tmp_5_22456963_C_G | 398 | C>S | No | 1000Genomes | |
| tmp_5_22456962_A_C | 398 | C>W | No | 1000Genomes | |
| tmp_5_22456936_C_T | 407 | G>E | No | 1000Genomes | |
| ENSVATH07425475 | 420 | R>G | No | 1000Genomes | |
| ENSVATH07425474 | 420 | R>I | No | 1000Genomes | |
| ENSVATH12782890 | 429 | V>A | No | 1000Genomes | |
| ENSVATH07425471 | 477 | N>D | No | 1000Genomes | |
| ENSVATH07425464 | 535 | S>L | No | 1000Genomes | |
| ENSVATH07425459 | 544 | S>I | No | 1000Genomes | |
| ENSVATH07425457 | 547 | S>N | No | 1000Genomes | |
| tmp_5_22455850_T_C | 610 | I>M | No | 1000Genomes | |
| ENSVATH07425431 | 642 | H>Y | No | 1000Genomes | |
| tmp_5_22455656_T_C | 675 | E>G | No | 1000Genomes | |
| tmp_5_22455654_C_T | 676 | V>I | No | 1000Genomes | |
| ENSVATH00735654 | 691 | T>P | No | 1000Genomes | |
| tmp_5_22455598_T_G | 694 | E>D | No | 1000Genomes | |
| ENSVATH03434166 | 698 | A>T | No | 1000Genomes | |
| ENSVATH14633729 | 699 | D>E | No | 1000Genomes | |
| tmp_5_22455545_G_A | 712 | A>V | No | 1000Genomes | |
| ENSVATH07425427 | 714 | E>D | No | 1000Genomes |
No associated diseases with Q9FJ70
5 regional properties for Q9FJ70
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Actinin-type actin-binding domain, conserved site | 213 - 237 | IPR001589 |
| domain | Calponin homology domain | 124 - 241 | IPR001715-1 |
| domain | Calponin homology domain | 269 - 372 | IPR001715-2 |
| domain | Calponin homology domain | 393 - 499 | IPR001715-3 |
| domain | Calponin homology domain | 514 - 622 | IPR001715-4 |
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| actin filament | A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane. |
| actin filament bundle | An assembly of actin filaments that are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness. |
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| plant-type vacuole | A closed structure that is completely surrounded by a unit membrane, contains liquid, and retains the same shape regardless of cell cycle phase. An example of this structure is found in Arabidopsis thaliana. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| actin filament binding | Binding to an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits. |
| metal ion binding | Binding to a metal ion. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| actin filament bundle assembly | The assembly of actin filament bundles; actin filaments are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness. |
| actin filament network formation | The assembly of a network of actin filaments; actin filaments on different axes and with differing orientations are crosslinked together to form a mesh of filaments. |
4 homologous proteins in AiPD
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSGFVGVIVS | DPWLQSQLTQ | VELRSLNSKF | VALKNQSGKV | TLEDLPSVLV | KVKSLSSSFK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| EKEIKEILGG | LGSDYESDDD | LDFESFLKVY | LNLRDKAADK | AGGGLKHSSS | FLKAGTTTLH |
| 130 | 140 | 150 | 160 | 170 | 180 |
| TINQSEKGSF | VLHINRYLGD | DPFLKQFLPL | DPDSNDLYEL | VKDGVLLCKL | INIAVPGTID |
| 190 | 200 | 210 | 220 | 230 | 240 |
| ERAINTKRVL | NPWERNENHT | LCLNSAKAVG | CSVVNIGTQD | LAEGRPHLVL | GLISQLIKIQ |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LLADLSLKKM | PQLVELVEDN | EDIEEFLRLP | PEKVLLKWMN | FHLKKGGYKK | TVGNFSSDLK |
| 310 | 320 | 330 | 340 | 350 | 360 |
| DAQAYAYLLN | VLAPEHCDPA | TLNAEDDLER | ANMVLEHAER | MNCKRYLTAE | EIVEGSSYLN |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LAFVAQIFHE | RNGLSTDGRF | SFAEMMTEDL | QTCRDERCYR | LWINSLGIES | YVNNVFEDVR |
| 430 | 440 | 450 | 460 | 470 | 480 |
| NGWILLEVVD | KVYPGSVNWK | QASKPPIKMP | FRKVENCNQV | VKIGKEMRFS | LVNVAGNDIV |
| 490 | 500 | 510 | 520 | 530 | 540 |
| QGNKKLILGF | LWQLMRTHML | QLLKSLRSRT | RGKDMTDSEI | ISWANRKVRI | MGRKSQIESF |
| 550 | 560 | 570 | 580 | 590 | 600 |
| KDKSLSSGLF | FLDLLWAVEP | RVVNWNLVTK | GESDDEKRLN | ATYIVSVARK | LGCSVFLLPE |
| 610 | 620 | 630 | 640 | 650 | 660 |
| DIVEVNQKMI | LILTASIMYW | SLQQQSSSSE | SSSSSSDSSS | THSTTTTCTS | TCTSTDASPA |
| 670 | 680 | 690 | 700 | 710 | |
| PSVTGEDEVS | SLNGEVSSLT | IEEDNEVSSL | TIEEDNDADI | LSDITSISEE | AANE |