AiPD: Autoinhibited Protein Database

Gene name	FIM5
Protein name	Fimbrin-5
Names	AtFIM5, Fimbrin-like protein 2, Fimbrin5
Species	Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway	ath:AT5G35700
EC number
Protein Class

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

59-148 (Predicted disordered autoinhibitory region) PR

59-148 (Predicted disordered autoinhibitory region)

cis-regPred

No accessory elements

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q9FKI0-F1	Predicted				AlphaFoldDB

Variant ID(s)	Position	Change	Diseaes Association	Provenance
tmp_5_13876350_G_A	28	S>F	No	1000Genomes
ENSVATH14518130	39	R>L	No	1000Genomes
tmp_5_13876226_A_G	40	F>S	No	1000Genomes
ENSVATH00674514	44	D>H	No	1000Genomes
ENSVATH07214648	69	D>G	No	1000Genomes
ENSVATH14518128	151	A>T	No	1000Genomes
ENSVATH07214644	154	A>S	No	1000Genomes
ENSVATH03243818	261	A>V	No	1000Genomes
tmp_5_13874737_G_A	304	A>V	No	1000Genomes
ENSVATH07214630	367	Q>H	No	1000Genomes
tmp_5_13874305_A_G	374	V>A	No	1000Genomes
tmp_5_13874269_G_A	386	T>I	No	1000Genomes
tmp_5_13874266_T_C	387	D>G	No	1000Genomes
ENSVATH11957926	400	L>F	No	1000Genomes
tmp_5_13874179_T_C	416	E>G	No	1000Genomes
ENSVATH07214621	423	V>I	No	1000Genomes
ENSVATH11957863	509	S>L	No	1000Genomes
tmp_5_13873468_G_T	541	D>E	No	1000Genomes
tmp_5_13873425_C_A	556	A>S	No	1000Genomes
ENSVATH03243812	569	N>S	No	1000Genomes
tmp_5_13873258_C_G	574	E>D	No	1000Genomes
tmp_5_13873070_C_T	609	M>I	No	1000Genomes
tmp_5_13873060_C_T	613	A>T	No	1000Genomes
tmp_5_13872994_C_T	635	A>T	No	1000Genomes
tmp_5_13872976_C_T	641	A>T	No	1000Genomes
ENSVATH03243799	645	A>S	No	1000Genomes
ENSVATH00674498	650	N>S	No	1000Genomes
tmp_5_13872930_G_C	656	A>G	No	1000Genomes
tmp_5_13872912_G_A	662	T>I	No	1000Genomes
ENSVATH03243798	664	Q>E	No	1000Genomes
tmp_5_13872901_G_C	666	Q>E	No	1000Genomes
ENSVATH07214606	680	D>E	No	1000Genomes
ENSVATH07214605	683	N>S	No	1000Genomes
ENSVATH07214604	684	N>I	No	1000Genomes
tmp_5_13872837_G_A	687	A>V	No	1000Genomes

Type	Name	Position	InterPro Accession
domain	Far11/STRP, N-terminal	48 - 354	IPR012486
domain	Far11/STRP, C-terminal	456 - 812	IPR021819

		Description
EC Number
Subcellular Localization	Cytoplasm, cytoskeleton
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

Name	Definition
actin filament	A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane.
actin filament bundle	An assembly of actin filaments that are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness.
cytoplasm	The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

Name	Definition
actin filament binding	Binding to an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits.

Name	Definition
actin cytoskeleton organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
actin filament bundle assembly	The assembly of actin filament bundles; actin filaments are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness.
actin filament network formation	The assembly of a network of actin filaments; actin filaments on different axes and with differing orientations are crosslinked together to form a mesh of filaments.
pollen germination	The physiological and developmental changes that occur in a heterosporous plant pollen grain, beginning with hydration and terminating with the emergence of the pollen tube through the aperture.
pollen tube growth	Growth of pollen via tip extension of the intine wall.

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
P13797	PLS3	Plastin-3	Homo sapiens (Human)	PR
Q9FJ70	FIM3	Fimbrin-3	Arabidopsis thaliana (Mouse-ear cress)	PR
Q9SJ84	FIM4	Fimbrin-4	Arabidopsis thaliana (Mouse-ear cress)	PR
Q7G188	FIM1	Fimbrin-1	Arabidopsis thaliana (Mouse-ear cress)	PR