Q9SEL7
Gene name |
DEGP5 (HHOA, At4g18370, F28J12.30) |
Protein name |
Protease Do-like 5, chloroplastic |
Names |
|
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT4G18370 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
2 structures for Q9SEL7
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 4IC5 | X-ray | 261 A | A/B/C | 73-322 | PDB |
| AF-Q9SEL7-F1 | Predicted | AlphaFoldDB |
40 variants for Q9SEL7
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH11973088 | 2 | T>N | No | 1000Genomes | |
| tmp_4_10149259_A_G | 9 | K>E | No | 1000Genomes | |
| tmp_4_10149263_C_A | 10 | A>D | No | 1000Genomes | |
| tmp_4_10149262_G_A | 10 | A>T | No | 1000Genomes | |
| ENSVATH06714421 | 12 | S>T | No | 1000Genomes | |
| ENSVATH02873411 | 13 | S>T | No | 1000Genomes | |
| ENSVATH06714422 | 15 | F>S | No | 1000Genomes | |
| tmp_4_10149284_C_T | 17 | T>I | No | 1000Genomes | |
| tmp_4_10149287_T_C | 18 | L>S | No | 1000Genomes | |
| ENSVATH02873415 | 21 | I>F | No | 1000Genomes | |
| ENSVATH06714423 | 22 | N>Y | No | 1000Genomes | |
| ENSVATH02873416 | 37 | D>N | No | 1000Genomes | |
| ENSVATH02873417 | 38 | V>A | No | 1000Genomes | |
| ENSVATH00519644 | 39 | I>V | No | 1000Genomes | |
| tmp_4_10149391_G_T | 53 | A>S | No | 1000Genomes | |
| ENSVATH02873420 | 57 | S>T | No | 1000Genomes | |
| ENSVATH06714426 | 62 | N>S | No | 1000Genomes | |
| tmp_4_10149430_C_T | 66 | L>F | No | 1000Genomes | |
| tmp_4_10149441_A_C | 69 | E>D | No | 1000Genomes | |
| ENSVATH06714427 | 76 | Q>R | No | 1000Genomes | |
| ENSVATH02873423 | 77 | F>L | No | 1000Genomes | |
| ENSVATH11973093 | 79 | E>D | No | 1000Genomes | |
| tmp_4_10149606_C_G | 100 | P>A | No | 1000Genomes | |
| ENSVATH06714433 | 103 | V>I | No | 1000Genomes | |
| tmp_4_10149624_G_A | 106 | E>K | No | 1000Genomes | |
| tmp_4_10149664_T_C | 119 | L>P | No | 1000Genomes | |
| tmp_4_10149672_G_A | 122 | E>K | No | 1000Genomes | |
| ENSVATH00519647 | 125 | G>A | No | 1000Genomes | |
| tmp_4_10149685_A_T | 126 | K>M | No | 1000Genomes | |
| ENSVATH00519648 | 139 | L>H | No | 1000Genomes | |
| tmp_4_10149845_A_G | 151 | K>R | No | 1000Genomes | |
| tmp_4_10149878_G_C | 162 | C>S | No | 1000Genomes | |
| ENSVATH06714440 | 185 | P>R | No | 1000Genomes | |
| ENSVATH02873438 | 189 | L>I | No | 1000Genomes | |
| tmp_4_10150194_G_A | 214 | V>I | No | 1000Genomes | |
| ENSVATH11973185 | 233 | I>T | No | 1000Genomes | |
| ENSVATH00519651 | 247 | N>S | No | 1000Genomes | |
| ENSVATH06714456 | 272 | D>N | No | 1000Genomes | |
| ENSVATH06714457 | 274 | Y>C | No | 1000Genomes | |
| ENSVATH11973192 | 309 | V>I | No | 1000Genomes |
No associated diseases with Q9SEL7
No regional properties for Q9SEL7
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q9SEL7 | |||
5 GO annotations of cellular component
| Name | Definition |
|---|---|
| chloroplast | A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma. |
| chloroplast thylakoid lumen | The cavity enclosed within the chloroplast thylakoid membrane. An example of this component is found in Arabidopsis thaliana. |
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| thylakoid | A membranous cellular structure that bears the photosynthetic pigments in plants, algae, and cyanobacteria. In cyanobacteria thylakoids are of various shapes and are attached to, or continuous with, the plasma membrane. In eukaryotes they are flattened, membrane-bounded disk-like structures located in the chloroplasts; in the chloroplasts of higher plants the thylakoids form dense stacks called grana. Isolated thylakoid preparations can carry out photosynthetic electron transport and the associated phosphorylation. |
| thylakoid lumen | The volume enclosed by a thylakoid membrane. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| serine-type endopeptidase activity | Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine). |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| photosystem II repair | Proteolysis of the damaged D1 protein and re-assembly of a new D1 subunit in the photosystem II following photoinhibition. |
| proteolysis | The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds. |
3 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q9SHZ0 | DEGP4 | Protease Do-like 4, mitochondrial | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O82261 | DEGP2 | Protease Do-like 2, chloroplastic | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q3E6S8 | DEGP14 | Putative protease Do-like 14 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTMALASSKA | FSSIFNTLSP | INQSKFVLAC | SGSNHVDVID | RRRRIMIFGS | SLALTSSLLG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SNQQRLPMES | AIALEQFKEK | EEELEEEEER | NVNLFQKTSP | SVVYIEAIEL | PKTSSGDILT |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DEENGKIEGT | GSGFVWDKLG | HIVTNYHVIA | KLATDQFGLQ | RCKVSLVDAK | GTRFSKEGKI |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VGLDPDNDLA | VLKIETEGRE | LNPVVLGTSN | DLRVGQSCFA | IGNPYGYENT | LTIGVVSGLG |
| 250 | 260 | 270 | 280 | 290 | 300 |
| REIPSPNGKS | ISEAIQTDAD | INSGNSGGPL | LDSYGHTIGV | NTATFTRKGS | GMSSGVNFAI |
| 310 | 320 | ||||
| PIDTVVRTVP | YLIVYGTAYR | DRF |