Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q3E6S8

Entry ID Method Resolution Chain Position Source
AF-Q3E6S8-F1 Predicted AlphaFoldDB

No variants for Q3E6S8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q3E6S8

No associated diseases with Q3E6S8

3 regional properties for Q3E6S8

Type Name Position InterPro Accession
domain PDZ domain 318 - 424 IPR001478
domain Peptidase M50 339 - 425 IPR008915
domain PDZ domain 6 364 - 401 IPR041489

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
serine-type endopeptidase activity Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).

1 GO annotations of biological process

Name Definition
proteolysis The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9SHZ0 DEGP4 Protease Do-like 4, mitochondrial Arabidopsis thaliana (Mouse-ear cress) PR
O82261 DEGP2 Protease Do-like 2, chloroplastic Arabidopsis thaliana (Mouse-ear cress) PR
Q9SEL7 DEGP5 Protease Do-like 5, chloroplastic Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MMNFLRRAVS SSKRSELIRI ISVATATSGI LYASTNPDAR TRVSLAIPES VRESLSLLPW
70 80 90 100 110 120
QISPGLIHRP EQSLFGNFVF SSRVSPKSEA PINDEKGVSV EASDSSSKPS NGYLGRDTIA
130 140 150 160 170 180
NAAARIGPAV VNLSVPQGFH GISMGKSIGS GTIIDADGTI LTCAHVVVDF QNIRHSSKGR
190 200 210 220 230 240
VDVTLQDGRT FEGVVVNADL QSDIALVKIK SKTPLPTAKL GFSSKLRPGD WVIAVGCPLS
250 260 270 280 290 300
LQNTVTAGIV SCVDRKSSDL GLGGKHREYL QTDCSINAGN SGGPLVNLDG EVIGVNIMKV
310 320 330 340 350 360
LAADGLGFSV PIDSVSKIIE HFKKSGRVIR PWIGLKMVEL NNLIVAQLKE RDPMFPDVER
370 380 390 400 410 420
GVLVPTVIPG SPADRAGFKP GDVVVRFDGK PVIEIMDDRV GKRMQVVVER SNKERVTLEV
IPEEANPDM