Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9R193

Entry ID Method Resolution Chain Position Source
AF-Q9R193-F1 Predicted AlphaFoldDB

No variants for Q9R193

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9R193

No associated diseases with Q9R193

No regional properties for Q9R193

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q9R193

Functions

Description
EC Number
Subcellular Localization
  • Nucleus inner membrane ; Single-pass type II membrane protein
  • Detected in nuclear envelops
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
chromatin The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome.
nuclear inner membrane The inner, i.e. lumen-facing, lipid bilayer of the nuclear envelope.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
sodium:potassium-exchanging ATPase complex Sodium:potassium-exchanging ATPases are tetrameric proteins, consisting of two large alpha subunits and two smaller beta subunits. The alpha subunits bear the active site and penetrate the membrane, while the beta subunits carry oligosaccharide groups and face the cell exterior.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

3 GO annotations of biological process

Name Definition
potassium ion transport The directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
regulation of DNA-templated transcription Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
sodium ion transport The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

4 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P08251 ATP1B1 Sodium/potassium-transporting ATPase subunit beta-1 Gallus gallus (Chicken) PR
Q9UN42 ATP1B4 Protein ATP1B4 Homo sapiens (Human) PR
Q99ME6 Atp1b4 Protein ATP1B4 Mus musculus (Mouse) PR
P05027 ATP1B1 Sodium/potassium-transporting ATPase subunit beta-1 Sus scrofa (Pig) PR
10 20 30 40 50 60
MRRQLRSRRA PAFPYGYRYR LDDQDEMNHN YLADEEEEAE EEAQVMMVPG LEEEEEEEEG
70 80 90 100 110 120
KEEEEEREEE EGQGQSTGNA WWRKLQIVNE YLWDPEKRMS LARTGQSRSL ILVIYFFFYA
130 140 150 160 170 180
SLAAVITLFI YMLFLAISPY MPTFTEQVKP PGVMIRPFAH SLNFNFNVSE PETWQRYVIS
190 200 210 220 230 240
LNGFLQGYND SLQEEMNIDC PPGQYFIQDG DEDEDKKACQ FKRSFLKNCS GLEDPTFGYS
250 260 270 280 290 300
TGQPCILLKM NRIVGFRPEF GDPVKVSCKV QKGDENDIRS INYYPESASF DLRYYPYYGK
310 320 330 340 350
LTHVNYTSPL VAMHFTDVVK NQEVPVQCQL KGKGIVNDVI NDRFVGRIIF TLNIET