P08251

PR
Gene name
ATP1B1
Protein name
Sodium/potassium-transporting ATPase subunit beta-1
Names
Sodium/potassium-dependent ATPase subunit beta-1
Species
Gallus gallus (Chicken)
KEGG Pathway
gga:396529
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-233 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P08251

Entry ID Method Resolution Chain Position Source
AF-P08251-F1 Predicted AlphaFoldDB

No variants for P08251

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P08251

No associated diseases with P08251

No regional properties for P08251

Type Name Position InterPro Accession
No domain, repeats, and functional sites for P08251

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Single-pass type II membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
sodium:potassium-exchanging ATPase complex Sodium:potassium-exchanging ATPases are tetrameric proteins, consisting of two large alpha subunits and two smaller beta subunits. The alpha subunits bear the active site and penetrate the membrane, while the beta subunits carry oligosaccharide groups and face the cell exterior.

1 GO annotations of molecular function

Name Definition
ATPase activator activity Binds to and increases the activity of an ATP hydrolysis activity.

4 GO annotations of biological process

Name Definition
cellular potassium ion homeostasis Any process involved in the maintenance of an internal steady state of potassium ions at the level of a cell.
cellular sodium ion homeostasis Any process involved in the maintenance of an internal steady state of sodium ions at the level of a cell.
potassium ion import across plasma membrane The directed movement of potassium ions from outside of a cell, across the plasma membrane and into the cytosol.
sodium ion export across plasma membrane The directed movement of sodium ions from inside of a cell, across the plasma membrane and into the extracellular region.

4 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9UN42 ATP1B4 Protein ATP1B4 Homo sapiens (Human) PR
Q99ME6 Atp1b4 Protein ATP1B4 Mus musculus (Mouse) PR
P05027 ATP1B1 Sodium/potassium-transporting ATPase subunit beta-1 Sus scrofa (Pig) PR
Q9R193 Atp1b4 Protein ATP1B4 Rattus norvegicus (Rat) PR
10 20 30 40 50 60
MARGKANDGD GNWKKFIWNS EKKELLGRTG GSWFKILLFY VIFYGCLAGI FIGTIQVMLL
70 80 90 100 110 120
TVSEFEPKYQ DRVAPPGLTQ VPQVQKTEIS FTVNDPKSYD PYVKNLEGFL NKYSAGEQTD
130 140 150 160 170 180
NIVFQDCGDI PTDYKERGPY NDAQGQKKVC KFKREWLENC SGLQDNTFGY KDGKPCILVK
190 200 210 220 230 240
LNRIIGFKPK APENESLPSD LAGKYNPYLI PVHCVAKRDE DADKIGMVEY YGMGGYPGFA
250 260 270 280 290 300
LQYYPYYGRL LQPQYLQPLV AVQFTNLTYD VEVRVECKEY GQNIQYSDKD RFQGRFDIKF
DIKSS