Q9PTJ6
Gene name |
NFI1 (NIF) |
Protein name |
CTD small phosphatase-like protein |
Names |
CTDSP-like, Nuclear LIM interactor-interacting factor 1, NLI-interacting factor 1, Small C-terminal domain phosphatase 3 |
Species |
Gallus gallus (Chicken) |
KEGG Pathway |
gga:408252 |
EC number |
3.1.3.16: Phosphoric monoester hydrolases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9PTJ6
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9PTJ6-F1 | Predicted | AlphaFoldDB |
No variants for Q9PTJ6
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q9PTJ6 | |||||
No associated diseases with Q9PTJ6
Functions
| Description | ||
|---|---|---|
| EC Number | 3.1.3.16 | Phosphoric monoester hydrolases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| metal ion binding | Binding to a metal ion. |
| myosin phosphatase activity | Catalysis of the reaction: phosphomyosin + H2O = myosin + phosphate. |
| phosphoprotein phosphatase activity | Catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate. Together with protein kinases, these enzymes control the state of phosphorylation of cellular proteins and thereby provide an important mechanism for regulating cellular activity. |
| RNA polymerase II CTD heptapeptide repeat phosphatase activity | Catalysis of the reaction: phospho-(DNA-directed RNA polymerase II) + H2O = (DNA-directed RNA polymerase II) + phosphate. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
3 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| O14595 | CTDSP2 | Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 | Homo sapiens (Human) | PR |
| P58465 | Ctdspl | CTD small phosphatase-like protein | Mus musculus (Mouse) | PR |
| Q8BX07 | Ctdsp2 | Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 | Mus musculus (Mouse) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MDNPSIITQV | TNPKEEEILS | CTQDKVSQCN | ISLKKQRSRS | IFSTLFCCFR | DYNVEPPSTN |
| 70 | 80 | 90 | 100 | 110 | 120 |
| STSALPPLVE | ENGGLQKGDQ | MQVMPIPSPP | AKYLLPELTA | SDYGKKCVVI | DLDETLVHSS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| FKPISNADFI | VPVEIDGTIH | QVYVLKRPHV | DEFLQRMGEL | FECVLFTASL | AKYADPVADL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LDRWGVFRAR | LFRESCVFHR | GNYVKDLSRL | GRELSKVIIV | DNSPASYIFH | PENAVPVQSW |
| 250 | 260 | 270 | |||
| FDDMTDTELL | DLIPFFEGLS | KEEEVYSMLH | KLCNR |