Q9NQG6
PR
Gene name |
MIEF1 (MID51, SMCR7L) |
Protein name |
Mitochondrial dynamics protein MID51 |
Names |
Mitochondrial dynamics protein of 51 kDa, Mitochondrial elongation factor 1, Smith-Magenis syndrome chromosomal region candidate gene 7 protein-like, SMCR7-like protein |
Species |
Homo sapiens (Human) |
KEGG Pathway |
hsa:54471 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
8 structures for Q9NQG6
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 4NXT | X-ray | 212 A | A/B/C/D | 119-463 | PDB |
| 4NXU | X-ray | 230 A | A/B/C/D | 119-463 | PDB |
| 4NXV | X-ray | 230 A | A/B/C/D | 119-463 | PDB |
| 4NXW | X-ray | 255 A | A | 119-463 | PDB |
| 4NXX | X-ray | 255 A | A | 119-463 | PDB |
| 5X9B | X-ray | 270 A | A | 133-463 | PDB |
| 5X9C | X-ray | 185 A | A/B | 133-463 | PDB |
| AF-Q9NQG6-F1 | Predicted | AlphaFoldDB |
375 variants for Q9NQG6
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
|
rs749536883 CA324425267 |
4 | A>T | No |
ClinGen gnomAD |
|
|
rs1245394195 CA411619612 |
4 | A>V | No |
ClinGen gnomAD |
|
|
CA411619616 rs1459515599 |
5 | G>D | No |
ClinGen TOPMed |
|
|
rs1601748924 CA411619623 |
6 | E>G | No |
ClinGen Ensembl |
|
|
CA10242519 rs150822596 |
7 | R>C | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs760871767 CA10242520 |
7 | R>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA411619639 rs1426441368 |
9 | G>S | No |
ClinGen gnomAD |
|
|
rs377585123 CA10242521 |
11 | K>T | No |
ClinGen ESP ExAC gnomAD |
|
|
CA324425290 rs28480299 |
14 | N>K | No |
ClinGen Ensembl |
|
|
rs541450664 CA10242522 |
18 | T>M | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs572762304 CA10242525 |
24 | L>F | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA10242527 rs780678940 |
26 | N>S | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs747457801 CA411619766 |
28 | R>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1338340725 CA411619767 |
28 | R>Q | No |
ClinGen TOPMed gnomAD |
|
|
rs747457801 CA10242528 |
28 | R>W | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA10242529 rs755670930 |
29 | L>M | No |
ClinGen ExAC gnomAD |
|
|
CA10242530 rs777237660 |
30 | V>G | No |
ClinGen ExAC gnomAD |
|
|
CA411619793 rs1601749042 |
33 | V>G | No |
ClinGen Ensembl |
|
|
CA324425345 rs976814958 |
36 | A>E | No |
ClinGen TOPMed gnomAD |
|
|
CA411619812 rs976814958 |
36 | A>V | No |
ClinGen TOPMed gnomAD |
|
|
rs770525005 CA10242532 |
38 | M>R | No |
ClinGen ExAC gnomAD |
|
|
rs966198823 CA324425350 |
38 | M>V | No |
ClinGen Ensembl |
|
|
rs1472803619 CA411619841 |
41 | I>T | No |
ClinGen gnomAD |
|
|
CA324425380 rs373075072 |
42 | A>G | No |
ClinGen ESP TOPMed gnomAD |
|
|
rs1477159815 COSM1034301 CA411619844 |
42 | A>T | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA TOPMed gnomAD |
|
CA411619848 rs373075072 |
42 | A>V | No |
ClinGen ESP TOPMed gnomAD |
|
|
rs1368577524 CA411619854 |
43 | T>M | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs1389579934 CA411619860 |
45 | A>T | No |
ClinGen gnomAD |
|
|
rs1455418253 CA411619872 |
47 | K>Q | No |
ClinGen TOPMed |
|
|
rs376035666 CA10242536 |
48 | R>Q | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs1382278328 CA411619905 |
50 | Y>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs569843822 CA324425753 |
51 | D>N | No |
ClinGen TOPMed |
|
|
CA324425758 rs1018542096 |
52 | R>Q | No |
ClinGen TOPMed gnomAD |
|
|
rs755440609 CA10242547 |
52 | R>W | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA324425764 rs144389397 |
53 | A>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs144389397 CA10242548 |
53 | A>T | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA10242549 rs373246269 COSM3390236 |
53 | A>V | pancreas [Cosmic] | No |
ClinGen cosmic curated ESP ExAC TOPMed gnomAD |
|
rs778690453 CA10242551 |
56 | A>V | No |
ClinGen ExAC gnomAD |
|
|
rs1601749530 CA411619947 TCGA novel |
57 | P>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA Ensembl |
|
rs200564203 CA324425797 |
60 | P>L | No |
ClinGen Ensembl |
|
|
CA324425806 rs866288576 |
61 | T>N | No |
ClinGen gnomAD |
|
|
CA10242554 rs775114728 |
61 | T>P | No |
ClinGen ExAC gnomAD |
|
|
CA10242556 rs553768655 |
62 | R>C | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA10242557 rs556813831 |
62 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD |
|
CA411619977 rs556813831 |
62 | R>L | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs762051525 CA10242558 |
64 | S>G | No |
ClinGen ExAC gnomAD |
|
|
rs1476648209 CA411619985 |
64 | S>N | No |
ClinGen TOPMed |
|
|
rs1569018637 CA411619994 |
65 | H>R | No |
ClinGen Ensembl |
|
|
rs200727999 CA10242560 |
66 | S>L | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs200727999 CA10242559 |
66 | S>W | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA324425848 rs887595777 |
68 | K>R | No |
ClinGen Ensembl |
|
|
CA10242562 rs766800569 |
69 | R>K | No |
ClinGen ExAC gnomAD |
|
|
rs558394876 CA324425854 |
69 | R>S | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs576752056 CA10242564 |
70 | S>C | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs767948904 CA10242565 |
71 | W>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs753195461 CA10242566 |
72 | E>K | No |
ClinGen ExAC gnomAD |
|
|
rs756813736 CA10242567 |
74 | P>L | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA411620059 rs1231760160 |
75 | N>S | No |
ClinGen TOPMed gnomAD |
|
|
CA411620069 rs1235911595 |
76 | W>C | No |
ClinGen gnomAD |
|
|
rs1317937096 CA411620064 |
76 | W>R | No |
ClinGen gnomAD |
|
|
CA324425945 rs991862528 |
76 | W>S | No |
ClinGen TOPMed gnomAD |
|
|
CA411620078 rs1457096054 |
77 | M>I | No |
ClinGen gnomAD |
|
|
CA10242569 VAR_037040 rs2272830 |
78 | G>R | No |
ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
rs771827471 CA324425951 |
78 | G>V | No |
ClinGen Ensembl |
|
|
CA10242570 rs757946795 |
80 | P>A | No |
ClinGen ExAC gnomAD |
|
|
CA324425958 rs953150767 |
81 | R>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen Ensembl NCI-TCGA |
|
CA411620107 rs1368488182 |
83 | L>P | No |
ClinGen TOPMed |
|
|
CA411620116 rs1424263795 |
84 | N>K | No |
ClinGen gnomAD |
|
|
rs1466146490 CA411620119 |
85 | R>K | No |
ClinGen TOPMed gnomAD |
|
|
CA10242572 rs377319480 |
86 | D>N | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA10242573 rs768717514 |
87 | M>L | No |
ClinGen ExAC gnomAD |
|
|
CA10242574 rs781337794 |
88 | K>E | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA411620142 rs1411739093 |
88 | K>R | No |
ClinGen TOPMed |
|
|
VAR_037041 RCV000965499 CA10242575 rs17001213 |
89 | T>M | No |
ClinGen ClinVar UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
rs140773816 CA10242577 |
90 | G>D | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 93 | R>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA10242579 rs771003764 |
93 | R>Q | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA10242578 rs144526373 |
93 | R>W | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA411620189 rs1219935524 |
96 | Q>R | No |
ClinGen gnomAD |
|
|
CA411620193 rs1601749798 |
97 | T>P | No |
ClinGen Ensembl |
|
|
rs767850819 CA10242582 |
99 | P>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs759964714 CA10242581 |
99 | P>S | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA411620212 rs1231966882 |
100 | T>K | No |
ClinGen TOPMed |
|
|
CA411620218 rs1601749824 |
101 | D>A | No |
ClinGen Ensembl |
|
|
rs1178962596 CA411620223 |
102 | S>A | No |
ClinGen TOPMed |
|
|
rs887495064 CA324426058 |
102 | S>F | No |
ClinGen TOPMed |
|
|
rs887495064 CA411620226 |
102 | S>Y | No |
ClinGen TOPMed |
|
|
rs1221468509 CA411620230 |
103 | S>A | No |
ClinGen gnomAD |
|
|
rs1210035300 CA411620233 |
103 | S>F | No |
ClinGen TOPMed |
|
|
rs552010977 CA10242586 |
104 | T>A | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA10242585 rs552010977 |
104 | T>P | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
TCGA novel CA411620242 rs1478795446 |
105 | F>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen gnomAD NCI-TCGA |
|
rs1282133580 CA411620246 |
106 | D>N | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
|
CA10242587 rs749851378 |
107 | T>A | No |
ClinGen ExAC gnomAD |
|
|
rs961206480 CA324426073 |
107 | T>I | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs12158456 CA10242606 |
112 | P>L | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs12158456 CA10242607 |
112 | P>Q | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs116266824 COSM1034302 CA10242610 |
114 | R>Q | endometrium [Cosmic] | No |
ClinGen cosmic curated 1000Genomes ESP ExAC TOPMed gnomAD |
|
rs371574555 CA10242609 |
114 | R>W | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1312773405 CA411620320 |
116 | K>E | No |
ClinGen gnomAD |
|
|
CA411620338 rs1569019045 |
118 | V>E | No |
ClinGen Ensembl |
|
|
rs1210896248 CA411620335 |
118 | V>L | No |
ClinGen gnomAD |
|
|
rs752486701 CA10242611 |
119 | A>S | No |
ClinGen ExAC gnomAD |
|
|
rs1460128341 CA411620343 |
119 | A>V | No |
ClinGen gnomAD |
|
| TCGA novel | 121 | K>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 121 | K>E | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA324426299 rs756326064 |
121 | K>R | No |
ClinGen Ensembl |
|
|
rs1601750223 CA411620368 |
123 | Q>R | No |
ClinGen Ensembl |
|
|
rs1601750230 CA411620377 |
124 | V>G | No |
ClinGen Ensembl |
|
| TCGA novel | 126 | L>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA10242614 rs777642593 |
130 | R>* | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
rs777642593 CA411620415 |
130 | R>G | No |
ClinGen ExAC gnomAD |
|
|
CA10242615 rs749239462 |
130 | R>Q | No |
ClinGen ExAC gnomAD |
|
|
CA10242616 rs757326981 |
132 | R>C | No |
ClinGen ExAC gnomAD |
|
|
rs368491896 CA10242617 |
132 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs368491896 CA324426371 |
132 | R>L | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA411620433 rs1257913380 |
133 | M>I | No |
ClinGen gnomAD |
|
|
CA10242618 rs746118182 |
136 | Q>* | No |
ClinGen ExAC gnomAD |
|
|
rs1356893643 CA411620472 |
139 | L>V | No |
ClinGen gnomAD |
|
|
rs111676774 CA411620483 |
141 | T>A | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA411620482 rs111676774 |
141 | T>P | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA10242619 rs111676774 |
141 | T>S | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA10242620 rs775843761 |
142 | Y>H | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 142 | Y>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA10242621 rs747269715 |
143 | Y>* | No |
ClinGen ExAC gnomAD |
|
|
COSM478979 CA10242623 rs777054252 |
144 | R>Q | kidney Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
rs769059682 CA10242622 |
144 | R>W | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs773951732 CA10242626 |
146 | R>Q | No |
ClinGen ExAC gnomAD |
|
|
rs778124994 CA324426427 |
146 | R>W | No |
ClinGen TOPMed gnomAD |
|
|
CA10242627 rs759278573 |
147 | A>V | No |
ClinGen ExAC gnomAD |
|
|
rs752393975 CA411620533 |
150 | P>A | No |
ClinGen ExAC gnomAD |
|
|
CA10242629 rs752393975 |
150 | P>T | No |
ClinGen ExAC gnomAD |
|
|
rs1447630497 CA411620541 |
151 | A>G | No |
ClinGen gnomAD |
|
|
rs755923901 CA10242630 |
151 | A>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA324426442 rs940734659 |
153 | E>K | No |
ClinGen TOPMed |
|
|
CA10242632 rs753754391 |
156 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA10242631 rs376769285 |
156 | R>W | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA324426467 rs868319070 |
157 | A>V | No |
ClinGen Ensembl |
|
|
rs757176310 CA10242633 |
158 | K>R | No |
ClinGen ExAC gnomAD |
|
|
rs1252208875 CA411620589 |
159 | Q>R | No |
ClinGen TOPMed |
|
|
rs1212034105 CA411620605 |
162 | V>M | No |
ClinGen TOPMed |
|
|
CA411620625 rs1468773494 |
164 | I>M | No |
ClinGen gnomAD |
|
|
rs778983712 CA411620626 |
165 | C>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs778983712 CA10242634 |
165 | C>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs2232088 VAR_037042 CA10242636 |
169 | R>W | No |
ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
rs1327908517 CA411620676 |
172 | L>P | No |
ClinGen gnomAD |
|
|
rs369835711 CA10242638 |
173 | R>Q | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs780321361 CA10242637 |
173 | R>W | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1272930378 CA411620683 |
174 | A>S | No |
ClinGen gnomAD |
|
|
CA10242639 rs768941796 |
175 | K>Q | No |
ClinGen ExAC gnomAD |
|
|
CA10242641 rs748626701 |
178 | D>E | No |
ClinGen ExAC gnomAD |
|
|
CA10242642 rs371769454 |
179 | M>I | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs375966687 CA10242643 |
180 | P>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 181 | L>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA411620734 rs1224246033 |
182 | R>Q | No |
ClinGen gnomAD |
|
|
rs771698108 CA10242645 |
182 | R>W | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA10242646 rs775059044 |
183 | D>V | No |
ClinGen ExAC gnomAD |
|
|
CA10242648 rs763823300 |
184 | M>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs760339504 CA10242647 |
184 | M>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1352332058 CA753079814 |
185 | Y>* | No |
ClinGen TOPMed |
|
|
CA411620761 rs1474161533 |
186 | L>S | No |
ClinGen gnomAD |
|
|
rs753617239 CA10242649 |
186 | L>V | No |
ClinGen ExAC gnomAD |
|
|
CA411620786 rs1601750538 |
189 | S>R | No |
ClinGen Ensembl |
|
|
CA10242651 rs765090634 |
189 | S>T | No |
ClinGen ExAC |
|
|
rs1022946628 CA324426596 |
190 | L>P | No |
ClinGen TOPMed |
|
|
rs757503154 CA324426620 |
191 | Y>* | No |
ClinGen ExAC gnomAD |
|
|
CA324426611 rs148957894 |
191 | Y>F | No |
ClinGen ESP TOPMed |
|
|
CA411620798 COSM1034305 rs1301122333 |
192 | D>N | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA TOPMed gnomAD |
|
rs780151482 CA10242654 |
193 | D>N | No |
ClinGen ExAC gnomAD |
|
|
rs1181318722 CA411620849 |
197 | V>G | No |
ClinGen TOPMed gnomAD |
|
|
CA411620846 rs1443671591 |
197 | V>M | No |
ClinGen gnomAD |
|
|
rs1361983414 CA411620881 |
202 | I>T | No |
ClinGen gnomAD |
|
|
rs199993786 CA10242676 |
202 | I>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1569019943 CA411620894 |
204 | L>F | No |
ClinGen Ensembl |
|
|
CA411620906 rs1202565474 |
206 | V>L | No |
ClinGen TOPMed |
|
|
rs778255699 CA411620914 |
207 | P>H | No |
ClinGen ExAC gnomAD |
|
|
CA10242679 rs778255699 |
207 | P>L | No |
ClinGen ExAC gnomAD |
|
|
CA10242680 rs749839535 |
211 | E>A | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 212 | Q>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA411620957 rs201294596 |
214 | L>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA324427667 rs989590737 |
215 | W>C | No |
ClinGen TOPMed gnomAD |
|
|
rs1309663074 CA411620974 |
216 | S>L | No |
ClinGen gnomAD |
|
|
rs776401340 CA10242685 |
217 | C>Y | No |
ClinGen ExAC gnomAD |
|
|
CA10242687 rs200542861 |
222 | D>G | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA10242686 rs138446352 |
222 | D>N | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs916942251 CA324427694 |
224 | I>T | No |
ClinGen Ensembl |
|
|
CA10242689 rs762892107 |
225 | M>T | No |
ClinGen ExAC gnomAD |
|
|
rs772943231 CA10242688 |
225 | M>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1569020015 CA411621038 |
226 | N>S | No |
ClinGen Ensembl |
|
|
CA411621052 rs1248203288 |
228 | P>L | No |
ClinGen gnomAD |
|
|
CA10242691 rs774154590 |
230 | F>C | No |
ClinGen ExAC gnomAD |
|
|
CA411621065 rs1354756896 |
230 | F>L | No |
ClinGen TOPMed |
|
|
rs1397554036 CA411621085 |
233 | V>A | No |
ClinGen TOPMed |
|
|
CA10242692 rs759722178 |
234 | R>H | No |
ClinGen ExAC gnomAD |
|
|
rs767475762 CA10242693 |
235 | R>C | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 236 | E>G | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA10242695 rs756360670 |
239 | E>Q | No |
ClinGen ExAC gnomAD |
|
|
CA10242696 rs764571206 |
240 | Y>* | No |
ClinGen ExAC |
|
|
rs754193765 CA10242697 |
241 | F>L | No |
ClinGen ExAC |
|
|
rs757705982 CA10242698 |
241 | F>L | No |
ClinGen ExAC gnomAD |
|
|
CA324427762 rs909642836 |
242 | P>A | No |
ClinGen Ensembl |
|
|
CA10242699 rs779538701 |
242 | P>L | No |
ClinGen ExAC gnomAD |
|
|
CA411621142 rs1394721735 |
243 | R>S | No |
ClinGen gnomAD |
|
|
rs1302504175 CA411621165 |
246 | S>N | No |
ClinGen gnomAD |
|
|
rs780650405 CA10242702 |
250 | R>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA411621197 rs1282144302 COSM478980 |
250 | R>H | kidney Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated NCI-TCGA gnomAD |
|
rs1426865946 CA411621205 |
251 | C>F | No |
ClinGen gnomAD |
|
| TCGA novel | 259 | P>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA10242703 rs747820697 |
261 | T>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs772998230 CA10242705 |
263 | A>T | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA10242706 rs2232091 VAR_037043 |
264 | D>N | No |
ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
CA10242709 rs759363646 |
270 | V>M | No |
ClinGen ExAC gnomAD |
|
|
CA324427900 rs372526147 |
271 | A>V | No |
ClinGen ESP |
|
|
CA411621343 rs1601752456 |
273 | S>A | No |
ClinGen Ensembl |
|
|
rs760988344 CA10242712 |
274 | I>L | No |
ClinGen ExAC gnomAD |
|
|
rs764342137 CA10242713 |
275 | N>K | No |
ClinGen ExAC |
|
|
rs1172727015 CA411621357 |
275 | N>S | No |
ClinGen gnomAD |
|
|
rs754105853 CA10242714 |
276 | W>C | No |
ClinGen ExAC gnomAD |
|
|
rs1371560520 CA411621365 |
276 | W>L | No |
ClinGen gnomAD |
|
|
rs919418159 CA324427959 |
277 | P>R | No |
ClinGen Ensembl |
|
|
rs757696205 CA411621373 |
278 | A>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA10242715 rs757696205 |
278 | A>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA411621384 rs1367978271 |
279 | I>M | No |
ClinGen gnomAD |
|
|
CA324427978 rs867109910 |
281 | S>F | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
|
rs186306472 CA10242717 |
284 | D>G | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA411621420 rs1340551214 |
285 | Y>C | No |
ClinGen gnomAD |
|
|
rs1187510859 CA411621426 |
286 | V>E | No |
ClinGen TOPMed |
|
|
CA10242718 rs758782871 |
286 | V>M | No |
ClinGen ExAC gnomAD |
|
|
CA10242719 rs201274653 |
288 | R>C | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs752136952 CA10242720 |
288 | R>L | No |
ClinGen ExAC gnomAD |
|
|
rs142835569 CA10242721 |
289 | P>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1355118088 CA411621448 |
290 | A>V | No |
ClinGen TOPMed |
|
|
CA324428055 rs1007522759 |
291 | P>R | No |
ClinGen Ensembl |
|
|
CA411621457 rs1489805689 |
292 | P>T | No |
ClinGen gnomAD |
|
|
CA411621464 rs1221602403 |
293 | P>S | No |
ClinGen gnomAD |
|
|
CA10242724 rs770803955 |
301 | Q>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1294626601 CA411621525 |
302 | Y>C | No |
ClinGen TOPMed |
|
|
CA10242726 rs778536607 |
304 | R>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
RCV000969385 CA10242727 rs141041315 |
304 | R>H | No |
ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
rs141041315 CA10242728 |
304 | R>P | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA10242729 rs775712595 |
305 | D>Y | No |
ClinGen ExAC gnomAD |
|
|
rs768845947 CA10242731 |
307 | H>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA411621567 rs1163427540 |
309 | F>I | No |
ClinGen gnomAD |
|
|
rs777044392 CA10242732 |
310 | I>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA411621597 rs1434442965 |
313 | L>V | No |
ClinGen gnomAD |
|
|
CA324428143 rs1051696830 |
314 | P>T | No |
ClinGen TOPMed gnomAD |
|
|
CA10242734 rs765666371 |
316 | V>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs747452310 CA324428153 |
318 | L>F | No |
ClinGen gnomAD |
|
|
rs143931307 CA10242736 |
319 | G>S | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs150255211 CA10242737 |
324 | V>A | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA411621671 rs1240480107 |
325 | A>V | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs752046797 CA10242738 |
326 | K>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1245202348 CA411621682 |
327 | P>L | No |
ClinGen gnomAD |
|
|
rs755667019 CA10242739 |
327 | P>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs755667019 CA10242740 |
327 | P>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1601752788 CA411621686 |
328 | H>P | No |
ClinGen Ensembl |
|
|
CA10242742 rs199511060 |
329 | R>Q | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs753555710 CA10242741 |
329 | R>W | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA411621701 rs1403006713 |
331 | A>D | No |
ClinGen gnomAD |
|
|
CA411621700 rs559558267 |
331 | A>S | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA10242743 rs559558267 |
331 | A>T | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs745585959 CA10242744 |
332 | Q>P | No |
ClinGen ExAC gnomAD |
|
|
CA324428226 rs1031951008 |
333 | Y>D | No |
ClinGen Ensembl |
|
|
CA324428221 rs1031951008 |
333 | Y>H | No |
ClinGen Ensembl |
|
| TCGA novel | 335 | N>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA411621733 rs1466110142 |
336 | L>M | No |
ClinGen gnomAD |
|
|
COSM40095 CA10242745 rs368627838 |
338 | R>Q | central_nervous_system [Cosmic] | No |
ClinGen cosmic curated ESP ExAC TOPMed gnomAD |
| TCGA novel | 339 | L>P | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA324428283 rs2232092 |
341 | L>P | No |
ClinGen TOPMed |
|
|
rs768898974 CA10242748 |
342 | R>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1003128148 COSM1241761 CA324428292 |
342 | R>H | oesophagus Variant assessed as Somatic; impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated NCI-TCGA TOPMed |
|
rs201517293 CA10242750 |
343 | P>S | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs544735642 CA411621777 |
344 | A>P | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA10242752 rs544735642 |
344 | A>T | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD |
|
CA10242753 rs146649231 |
344 | A>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1460197616 CA411621787 |
345 | E>D | No |
ClinGen gnomAD |
|
|
rs752098023 CA10242755 |
346 | T>M | Variant assessed as Somatic; 4.766e-05 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA10242758 rs140177103 |
348 | R>C | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs142436343 CA10242759 |
348 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA gnomAD |
|
CA411621809 rs372721188 |
350 | R>G | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA411621812 rs1249093190 |
350 | R>Q | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
rs372721188 CA10242761 |
350 | R>W | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs1178050900 CA411621815 |
351 | A>S | No |
ClinGen gnomAD |
|
|
rs1178050900 CA411621813 |
351 | A>T | No |
ClinGen gnomAD |
|
|
CA411621835 rs1203007810 |
354 | Q>P | No |
ClinGen TOPMed |
|
|
rs758320288 CA10242762 |
356 | D>N | No |
ClinGen ExAC gnomAD |
|
|
CA10242763 rs779965865 |
357 | S>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA411621862 rs1356018495 |
358 | G>A | No |
ClinGen gnomAD |
|
|
CA411621869 rs1439757573 |
359 | C>F | No |
ClinGen gnomAD |
|
|
rs1413487850 CA411621872 |
360 | R>* | No |
ClinGen TOPMed gnomAD |
|
|
rs746975740 CA10242765 |
360 | R>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA10242764 COSM1751883 rs746975740 |
360 | R>Q | Variant assessed as Somatic; 0.0 impact. urinary_tract breast [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
CA411621887 rs1569020505 |
362 | L>P | No |
ClinGen Ensembl |
|
|
rs1224194036 CA411621898 |
364 | L>F | No |
ClinGen gnomAD |
|
|
CA10242767 rs781336501 |
365 | K>R | No |
ClinGen ExAC gnomAD |
|
|
CA10242768 rs781336501 |
365 | K>T | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 366 | I>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA324428464 rs866567196 |
366 | I>V | No |
ClinGen Ensembl |
|
|
CA411621921 rs1350610798 |
368 | K>E | No |
ClinGen gnomAD |
|
| TCGA novel | 371 | C>G | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA10242769 rs769902754 |
371 | C>R | No |
ClinGen ExAC gnomAD |
|
|
rs1439863674 CA411621946 |
371 | C>W | No |
ClinGen TOPMed gnomAD |
|
|
CA10242770 rs773353465 |
371 | C>Y | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA10242771 rs749478962 |
375 | P>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1399619776 CA411621979 |
377 | L>V | No |
ClinGen TOPMed |
|
|
CA324428486 rs929482179 |
378 | G>S | No |
ClinGen TOPMed gnomAD |
|
|
rs987565346 CA411621995 |
379 | H>Q | No |
ClinGen TOPMed |
|
|
CA411621998 rs1179891125 |
380 | L>F | No |
ClinGen TOPMed |
|
| TCGA novel | 381 | T>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs760044793 CA10242774 |
381 | T>I | No |
ClinGen ExAC gnomAD |
|
|
rs767849879 CA10242775 |
383 | S>R | No |
ClinGen ExAC gnomAD |
|
|
CA411622031 rs1252216615 |
385 | L>Q | No |
ClinGen TOPMed |
|
|
CA10242776 rs199560314 |
386 | T>I | No |
ClinGen ExAC |
|
|
CA411622040 rs1411459910 |
387 | N>D | No |
ClinGen gnomAD |
|
|
rs557568950 CA10242777 |
387 | N>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs750085633 CA10242779 |
391 | H>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs201383905 CA10242780 |
393 | A>P | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA10242781 rs766301038 |
393 | A>V | No |
ClinGen ExAC gnomAD |
|
|
rs754815222 CA10242783 |
398 | D>V | No |
ClinGen ExAC gnomAD |
|
|
rs751342205 CA10242782 COSM323486 |
398 | D>Y | lung [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
|
rs781048132 CA411622132 |
400 | S>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs781048132 CA10242784 |
400 | S>Y | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs748094403 CA10242785 |
401 | P>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA10242786 rs748094403 |
401 | P>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1225316692 CA411622137 |
402 | D>N | No |
ClinGen gnomAD |
|
|
CA10242788 rs749530383 |
403 | M>T | No |
ClinGen ExAC gnomAD |
|
|
rs904510879 CA324428657 |
406 | D>N | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
rs747740427 CA10242790 |
407 | R>C | No |
ClinGen ExAC gnomAD |
|
|
rs746302171 CA10242791 |
407 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
rs1166990326 CA411622186 |
409 | L>P | No |
ClinGen gnomAD |
|
|
rs772473753 CA10242792 |
411 | A>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA10242793 rs775912326 |
412 | L>F | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
| TCGA novel | 414 | G>E | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 415 | L>F | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA324428715 rs768611628 |
415 | L>H | No |
ClinGen Ensembl |
|
|
rs1386282092 CA411622230 COSM1178637 |
416 | I>M | Variant assessed as Somatic; 0.0 impact. prostate [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA TOPMed gnomAD |
|
CA10242795 rs376697509 |
416 | I>T | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs772800218 CA10242796 |
417 | S>N | No |
ClinGen ExAC gnomAD |
|
|
rs1328404980 CA411622241 |
418 | Y>S | No |
ClinGen gnomAD |
|
|
CA10242799 rs751242262 |
423 | V>G | No |
ClinGen ExAC gnomAD |
|
|
CA324428741 rs1053206945 |
423 | V>I | No |
ClinGen TOPMed |
|
|
rs1290196717 CA411622289 |
426 | S>G | No |
ClinGen gnomAD |
|
|
rs752605750 CA10242802 |
427 | A>P | No |
ClinGen ExAC TOPMed |
|
|
rs752605750 CA411622296 |
427 | A>T | No |
ClinGen ExAC TOPMed |
|
|
rs1412612696 CA411622305 |
428 | L>R | No |
ClinGen TOPMed |
|
|
rs756027517 COSM1034307 CA10242803 |
431 | K>N | endometrium [Cosmic] | No |
ClinGen cosmic curated ExAC gnomAD |
|
CA324428768 rs200056180 |
431 | K>R | No |
ClinGen 1000Genomes |
|
|
rs140535562 CA324428775 |
435 | F>L | No |
ClinGen ESP |
|
|
rs1285800094 CA411622348 |
435 | F>L | No |
ClinGen gnomAD |
|
|
rs753843849 CA10242805 |
437 | E>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs376908468 CA324428801 |
437 | E>Q | No |
ClinGen Ensembl |
|
|
rs772983602 CA10242807 |
438 | L>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA10242808 rs746070942 |
438 | L>P | No |
ClinGen ExAC gnomAD |
|
|
CA10242809 rs150433194 |
439 | T>I | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA10242811 rs747494414 |
440 | P>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs780429146 CA10242810 |
440 | P>T | No |
ClinGen ExAC gnomAD |
|
|
CA324428855 rs905789644 |
442 | E>G | No |
ClinGen TOPMed gnomAD |
|
|
CA10242813 rs772853422 |
443 | I>T | No |
ClinGen ExAC gnomAD |
|
|
CA411622411 rs1454910952 |
445 | E>A | No |
ClinGen gnomAD |
|
|
CA10242816 rs536286318 |
445 | E>K | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ExAC NCI-TCGA TOPMed |
|
rs1240344366 CA411622434 |
448 | Y>C | No |
ClinGen gnomAD |
|
|
CA411622430 rs1340368597 |
448 | Y>H | No |
ClinGen gnomAD |
|
|
CA10242818 rs762638970 |
449 | T>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA411622458 rs1204101306 |
452 | C>Y | No |
ClinGen gnomAD |
|
|
rs752475555 CA10242820 |
453 | S>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA411622473 rs1462410096 |
454 | L>F | No |
ClinGen TOPMed gnomAD |
|
|
CA10242821 rs760530375 |
455 | S>C | No |
ClinGen ExAC gnomAD |
|
|
rs1183818696 CA411622492 |
457 | P>R | No |
ClinGen gnomAD |
|
|
CA411622488 rs1419485691 |
457 | P>S | No |
ClinGen gnomAD |
|
| TCGA novel | 458 | E>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA10242824 rs373709239 |
458 | E>Q | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1158604517 CA411622501 |
459 | V>M | No |
ClinGen TOPMed gnomAD |
|
|
CA324428914 rs187514447 |
462 | Q>E | No |
ClinGen 1000Genomes |
|
|
CA10242825 rs149438399 |
463 | T>M | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs1334992283 CA411622535 |
464 | T>Y | No |
ClinGen gnomAD |
No associated diseases with Q9NQG6
1 regional properties for Q9NQG6
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Mab-21-like, HhH/H2TH-like domain | 359 - 446 | IPR046906 |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| mitochondrial outer membrane | The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope. |
| mitochondrion | A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| ADP binding | Binding to ADP, adenosine 5'-diphosphate. |
| GDP binding | Binding to GDP, guanosine 5'-diphosphate. |
| identical protein binding | Binding to an identical protein or proteins. |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| cellular response to hypoxia | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level. |
| mitochondrial fission | The division of a mitochondrion within a cell to form two or more separate mitochondrial compartments. |
| positive regulation of mitochondrial fission | Any process that increases the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments. |
| positive regulation of protein targeting to membrane | Any process that increases the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein. |
4 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q8BGV8 | Mief1 | Mitochondrial dynamics protein MID51 | Mus musculus (Mouse) | PR |
| Q5NCS9 | Mief2 | Mitochondrial dynamics protein MID49 | Mus musculus (Mouse) | PR |
| Q5XIS8 | Mief1 | Mitochondrial dynamics protein MID51 | Rattus norvegicus (Rat) | PR |
| Q52MA5 | mief1 | Mitochondrial dynamics protein MID51 | Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAGAGERKGK | KDDNGIGTAI | DFVLSNARLV | LGVGGAAMLG | IATLAVKRMY | DRAISAPTSP |
| 70 | 80 | 90 | 100 | 110 | 120 |
| TRLSHSGKRS | WEEPNWMGSP | RLLNRDMKTG | LSRSLQTLPT | DSSTFDTDTF | CPPRPKPVAR |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KGQVDLKKSR | LRMSLQEKLL | TYYRNRAAIP | AGEQARAKQA | AVDICAELRS | FLRAKLPDMP |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LRDMYLSGSL | YDDLQVVTAD | HIQLIVPLVL | EQNLWSCIPG | EDTIMNVPGF | FLVRRENPEY |
| 250 | 260 | 270 | 280 | 290 | 300 |
| FPRGSSYWDR | CVVGGYLSPK | TVADTFEKVV | AGSINWPAIG | SLLDYVIRPA | PPPEALTLEV |
| 310 | 320 | 330 | 340 | 350 | 360 |
| QYERDKHLFI | DFLPSVTLGD | TVLVAKPHRL | AQYDNLWRLS | LRPAETARLR | ALDQADSGCR |
| 370 | 380 | 390 | 400 | 410 | 420 |
| SLCLKILKAI | CKSTPALGHL | TASQLTNVIL | HLAQEEADWS | PDMLADRFLQ | ALRGLISYLE |
| 430 | 440 | 450 | 460 | ||
| AGVLPSALNP | KVNLFAELTP | EEIDELGYTL | YCSLSEPEVL | LQT |