Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9LZ45

Entry ID Method Resolution Chain Position Source
AF-Q9LZ45-F1 Predicted AlphaFoldDB

10 variants for Q9LZ45

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_5_577137_C_T 2 A>T No 1000Genomes
tmp_5_577116_G_T 9 P>T No 1000Genomes
tmp_5_577095_G_A 16 P>S No 1000Genomes
ENSVATH00602281 25 E>D No 1000Genomes
tmp_5_577062_C_T 27 G>R No 1000Genomes
ENSVATH06909944 33 K>E No 1000Genomes
ENSVATH13885824 34 K>N No 1000Genomes
ENSVATH03010052 41 S>N No 1000Genomes
tmp_5_576953_G_T 63 S>Y No 1000Genomes
ENSVATH03010049 80 K>N No 1000Genomes

No associated diseases with Q9LZ45

No regional properties for Q9LZ45

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q9LZ45

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
  • Chromosome
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
nucleosome A complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA into higher order structures.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

3 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
protein heterodimerization activity Binding to a nonidentical protein to form a heterodimer.
structural constituent of chromatin The action of a molecule that contributes to the structural integrity of chromatin.

1 GO annotations of biological process

Name Definition
nucleosome assembly The aggregation, arrangement and bonding together of a nucleosome, the beadlike structural units of eukaryotic chromatin composed of histones and DNA.

5 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q96A08 H2BC1 Histone H2B type 1-A Homo sapiens (Human) PR
P70696 H2bc1 Histone H2B type 1-A Mus musculus (Mouse) PR
Q9SF55 At3g09480 Histone H2B.5 Arabidopsis thaliana (Mouse-ear cress) PR
O65821 H2B-1 Histone H2B.1 Solanum lycopersicum (Tomato) (Lycopersicon esculentum) PR
O65818 H2B-2 Histone H2B.2 Solanum lycopersicum (Tomato) (Lycopersicon esculentum) PR
10 20 30 40 50 60
MAPKAEKKPA EKAPAPKAEK KIAKEGGTSE IVKKKKKTKK STETYKIYIF KVLKQVHPDI
70 80 90 100 110 120
GISGKAMGIM NSFINDIFEK LAQESSRLAR YNKKPTITSR EIQTAVRLVL PGELAKHAVS
130
EGTKAVTKFT SS