AiPD: Autoinhibited Protein Database

Gene name	PHB5 (At5g14300, F18O22.90)
Protein name	Prohibitin-5, mitochondrial
Names	Atphb5
Species	Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway	ath:AT5G14300
EC number
Protein Class

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

128-227 (Predicted disordered autoinhibitory region) PR

128-227 (Predicted disordered autoinhibitory region)

cis-regPred

No accessory elements

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q9LY99-F1	Predicted				AlphaFoldDB

Variant ID(s)	Position	Change	Diseaes Association	Provenance
ENSVATH06965642	7	T>S	No	1000Genomes
tmp_5_4613136_G_A	12	G>D	No	1000Genomes
ENSVATH00621625	15	A>D	No	1000Genomes
ENSVATH08411069	17	I>L	No	1000Genomes
ENSVATH03055456	20	V>A	No	1000Genomes
tmp_5_4613165_T_C	22	S>P	No	1000Genomes
tmp_5_4613183_G_A	28	D>N	No	1000Genomes
ENSVATH06965644	30	G>V	No	1000Genomes
ENSVATH06965645	31	Q>*	No	1000Genomes
ENSVATH06965646	33	A>P	No	1000Genomes
tmp_5_4613207_T_A	36	F>I	No	1000Genomes
ENSVATH06965647	51	T>R	No	1000Genomes
tmp_5_4613286_A_G	62	Y>C	No	1000Genomes
tmp_5_4613298_T_A	66	I>N	No	1000Genomes
tmp_5_4613327_G_A	76	D>N	No	1000Genomes
tmp_5_4613370_G_C	90	R>P	No	1000Genomes
ENSVATH06965649	91	V>L	No	1000Genomes
tmp_5_4613571_G_A	100	A>T	No	1000Genomes
ENSVATH00621627	103	A>T	No	1000Genomes
tmp_5_4613600_G_C	109	E>D	No	1000Genomes
ENSVATH14024474	122	R>G	No	1000Genomes
ENSVATH14024625	143	G>D	No	1000Genomes
ENSVATH06965655	144	L>F	No	1000Genomes
ENSVATH00621628	151	S>L	No	1000Genomes
tmp_5_4613731_C_T	153	A>V	No	1000Genomes
tmp_5_4613756_G_C	161	Q>H	No	1000Genomes
tmp_5_4613821_T_C	183	I>T	No	1000Genomes
ENSVATH03055460	184	R>K	No	1000Genomes
ENSVATH00621629	189	S>T	No	1000Genomes
tmp_5_4613851_G_A	193	R>Q	No	1000Genomes
ENSVATH06965656	196	S>*	No	1000Genomes
ENSVATH06965657	197	K>E	No	1000Genomes
ENSVATH03055461	201	G>E	No	1000Genomes
ENSVATH06965659	219	A>V	No	1000Genomes
tmp_5_4613949_C_T	226	P>S	No	1000Genomes
ENSVATH03055463	227	N>H	No	1000Genomes
ENSVATH06965661	244	P>R	No	1000Genomes

Type	Name	Position	InterPro Accession
No domain, repeats, and functional sites for Q9LY99

		Description
EC Number
Subcellular Localization	Mitochondrion inner membrane ; Single-pass type II membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

Name	Definition
integral component of membrane	The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
mitochondrial inner membrane	The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
mitochondrion	A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

Name	Definition
No GO annotations for molecular function

Name	Definition
mitochondrion organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components.

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
Q3T165	PHB1	Prohibitin 1	Bos taurus (Bovine)	PR
P84173	PHB1	Prohibitin 1	Gallus gallus (Chicken)	PR
P35232	PHB1	Prohibitin 1	Homo sapiens (Human)	PR
Q9LK25	PHB4	Prohibitin-4, mitochondrial	Arabidopsis thaliana (Mouse-ear cress)	PR