Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9LRM5

Entry ID Method Resolution Chain Position Source
AF-Q9LRM5-F1 Predicted AlphaFoldDB

50 variants for Q9LRM5

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH10930985 7 K>N No 1000Genomes
ENSVATH10930986 11 A>S No 1000Genomes
tmp_3_8774668_C_T 11 A>V No 1000Genomes
tmp_3_8774728_A_G 31 N>S No 1000Genomes
ENSVATH13990824 32 N>I No 1000Genomes
tmp_3_8774730_A_T 32 N>Y No 1000Genomes
tmp_3_8775089_C_A 42 T>K No 1000Genomes
tmp_3_8775105_C_A 47 S>R No 1000Genomes
ENSVATH05902457 66 H>Q No 1000Genomes
ENSVATH00344922 70 D>G No 1000Genomes
ENSVATH00344923 75 A>T No 1000Genomes
ENSVATH05902458 81 L>I No 1000Genomes
ENSVATH05902466 85 S>G No 1000Genomes
tmp_3_8775994_C_T 99 S>L No 1000Genomes
ENSVATH02191848 108 D>A No 1000Genomes
tmp_3_8776025_T_G 109 C>W No 1000Genomes
ENSVATH10931055 126 C>S No 1000Genomes
ENSVATH02191849 151 D>Y No 1000Genomes
ENSVATH05902467 152 D>N No 1000Genomes
tmp_3_8776169_G_C 157 K>N No 1000Genomes
ENSVATH02191850 158 P>Q No 1000Genomes
ENSVATH13990881 173 I>V No 1000Genomes
tmp_3_8776398_G_C 234 V>L No 1000Genomes
ENSVATH10931056 236 V>I No 1000Genomes
ENSVATH10931056 236 V>L No 1000Genomes
ENSVATH10931057 243 A>P No 1000Genomes
tmp_3_8776459_T_A 254 I>N No 1000Genomes
tmp_3_8776467_T_C 257 F>L No 1000Genomes
ENSVATH10931058 260 S>N No 1000Genomes
tmp_3_8776527_G_T 277 V>F No 1000Genomes
tmp_3_8776540_A_G 281 N>S No 1000Genomes
tmp_3_8776692_C_T 304 H>Y No 1000Genomes
ENSVATH05902471 310 R>Q No 1000Genomes
ENSVATH00344927 313 M>I No 1000Genomes
ENSVATH10931076 314 M>I No 1000Genomes
ENSVATH10931077 318 V>I No 1000Genomes
tmp_3_8776766_A_G 328 I>M No 1000Genomes
tmp_3_8776904_A_T 345 D>V No 1000Genomes
tmp_3_8776949_C_G 360 P>R No 1000Genomes
ENSVATH10931080 368 R>I No 1000Genomes
tmp_3_8776981_G_T 371 A>S No 1000Genomes
ENSVATH13990882 377 A>V No 1000Genomes
ENSVATH05902472 379 E>G No 1000Genomes
tmp_3_8777137_G_A 397 R>K No 1000Genomes
ENSVATH05902475 400 K>* No 1000Genomes
ENSVATH00344930 429 P>R No 1000Genomes
ENSVATH05902477 438 A>V No 1000Genomes
ENSVATH02191856 449 K>E No 1000Genomes
tmp_3_8777296_C_A 450 P>H No 1000Genomes
tmp_3_8777301_T_A 452 Y>N No 1000Genomes

No associated diseases with Q9LRM5

5 regional properties for Q9LRM5

Type Name Position InterPro Accession
domain Rho GTPase-activating protein domain 380 - 564 IPR000198
domain Pleckstrin homology domain 265 - 370 IPR001849
domain BAR domain 6 - 249 IPR004148
domain GRAF, PH domain 267 - 370 IPR047225
domain Oligophrenin-1, BAR domain 19 - 225 IPR047267

Functions

Description
EC Number 4.2.2.2 Acting on polysaccharides
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
metal ion binding Binding to a metal ion.
pectate lyase activity Catalysis of the reaction: a pectate = a pectate + a pectate oligosaccharide with 4-(4-deoxy-alpha-D-galact-4-enuronosyl)-D-galacturonate end. This reaction is the eliminative cleavage of pectate to give oligosaccharides with 4-deoxy-alpha-D-gluc-4-enuronosyl groups at their non-reducing ends.

1 GO annotations of biological process

Name Definition
pectin catabolic process The chemical reactions and pathways resulting in the breakdown of pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues.

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9M9S2 AT59 Probable pectate lyase 3 Arabidopsis thaliana (Mouse-ear cress) PR
O64510 At2g02720 Probable pectate lyase 6 Arabidopsis thaliana (Mouse-ear cress) PR
Q944R1 At4g13710 Probable pectate lyase 15 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MATSSLKLTS ACFVLLFIFV GCVLTATNLR NNEISRSRKL KTEDSKSFNS SPMTTRLDGV
70 80 90 100 110 120
VELNEHAVTD PDKVAHEVSN LIHMSEQNIT ARRKLGFFSC GNGNLIDDCW RCDRNWNKNR
130 140 150 160 170 180
KHLADCGMGF GSKAFGGRNG SYYVVTDHSD DDVVNPKPGT LRHAVIQVEP LWIIFKRDMV
190 200 210 220 230 240
IKLKQELIMN SFKTIDARGA NVHIANGACI TIQNITNVIV HGLHIHDCKR TGNVTVRSSP
250 260 270 280 290 300
SQAGFRGTAD GDAINIFGSS HIWIDHNSLS NCTDGLVDVV NGSTAITISN NHFTHHDEVM
310 320 330 340 350 360
LLGHNDSYTR DKMMQVTVAY NHFGEGLIQR MPRCRHGYFH VVNNDYTHWK MYAIGGSANP
370 380 390 400 410 420
TINSQGNRFA APKNHSAKEV TKRLDTKGNE WMEWNWRSEK DLLVNGAFFT PSGEGASGDS
430 440 450
QTLSLPAKPA SMVDAITASA GALSCRRGKP CY