O64510
Gene name |
At2g02720 (T20F6.14) |
Protein name |
Probable pectate lyase 6 |
Names |
|
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT2G02720 |
EC number |
4.2.2.2: Acting on polysaccharides |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O64510
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O64510-F1 | Predicted | AlphaFoldDB |
49 variants for O64510
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH05221179 | 6 | S>G | No | 1000Genomes | |
| ENSVATH05221181 | 12 | V>I | No | 1000Genomes | |
| ENSVATH10714160 | 13 | A>P | No | 1000Genomes | |
| ENSVATH10714160 | 13 | A>S | No | 1000Genomes | |
| ENSVATH10714161 | 13 | A>V | No | 1000Genomes | |
| ENSVATH05221182 | 17 | T>S | No | 1000Genomes | |
| tmp_2_763257_G_A | 29 | E>K | No | 1000Genomes | |
| ENSVATH05221186 | 52 | N>K | No | 1000Genomes | |
| ENSVATH00202804 | 54 | E>D | No | 1000Genomes | |
| ENSVATH10714162 | 55 | N>T | No | 1000Genomes | |
| tmp_2_763361_T_G | 63 | H>Q | No | 1000Genomes | |
| ENSVATH10714163 | 65 | A>T | No | 1000Genomes | |
| ENSVATH10714227 | 68 | M>T | No | 1000Genomes | |
| ENSVATH05221193 | 70 | T>S | No | 1000Genomes | |
| ENSVATH01618882 | 73 | I>V | No | 1000Genomes | |
| tmp_2_763497_G_A | 76 | E>K | No | 1000Genomes | |
| ENSVATH05221195 | 86 | R>H | No | 1000Genomes | |
| ENSVATH00202807 | 90 | T>K | No | 1000Genomes | |
| tmp_2_763546_G_A | 92 | R>K | No | 1000Genomes | |
| ENSVATH13889301 | 93 | R>G | No | 1000Genomes | |
| tmp_2_763575_G_A | 102 | A>T | No | 1000Genomes | |
| tmp_2_763594_G_A | 108 | R>Q | No | 1000Genomes | |
| tmp_2_763599_G_A | 110 | D>N | No | 1000Genomes | |
| tmp_2_763642_T_C | 124 | V>A | No | 1000Genomes | |
| ENSVATH05221197 | 125 | L>F | No | 1000Genomes | |
| tmp_2_763661_A_T | 130 | K>N | No | 1000Genomes | |
| ENSVATH10714232 | 166 | R>Q | No | 1000Genomes | |
| tmp_2_763783_T_C | 171 | I>T | No | 1000Genomes | |
| tmp_2_763789_C_A | 173 | A>E | No | 1000Genomes | |
| ENSVATH05221201 | 174 | R>K | No | 1000Genomes | |
| tmp_2_763795_G_A | 175 | S>N | No | 1000Genomes | |
| ENSVATH10714234 | 197 | A>V | No | 1000Genomes | |
| ENSVATH10714285 | 205 | A>S | No | 1000Genomes | |
| ENSVATH05221206 | 216 | I>V | No | 1000Genomes | |
| tmp_2_763948_A_G | 226 | K>R | No | 1000Genomes | |
| tmp_2_764033_T_G | 254 | F>L | No | 1000Genomes | |
| ENSVATH13889302 | 294 | D>N | No | 1000Genomes | |
| ENSVATH13889405 | 305 | D>N | No | 1000Genomes | |
| tmp_2_764308_A_T | 309 | K>M | No | 1000Genomes | |
| tmp_2_764413_C_T | 344 | T>I | No | 1000Genomes | |
| tmp_2_764416_A_G | 345 | H>R | No | 1000Genomes | |
| tmp_2_764433_A_C | 351 | I>L | No | 1000Genomes | |
| ENSVATH05221212 | 362 | Q>H | No | 1000Genomes | |
| tmp_2_764503_C_T | 374 | S>F | No | 1000Genomes | |
| ENSVATH10714356 | 377 | V>I | No | 1000Genomes | |
| ENSVATH10714359 | 390 | S>L | No | 1000Genomes | |
| ENSVATH00202819 | 417 | A>P | No | 1000Genomes | |
| tmp_2_764733_A_G | 423 | I>V | No | 1000Genomes | |
| ENSVATH05221219 | 436 | K>M | No | 1000Genomes |
No associated diseases with O64510
Functions
| Description | ||
|---|---|---|
| EC Number | 4.2.2.2 | Acting on polysaccharides |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| metal ion binding | Binding to a metal ion. |
| pectate lyase activity | Catalysis of the reaction: a pectate = a pectate + a pectate oligosaccharide with 4-(4-deoxy-alpha-D-galact-4-enuronosyl)-D-galacturonate end. This reaction is the eliminative cleavage of pectate to give oligosaccharides with 4-deoxy-alpha-D-gluc-4-enuronosyl groups at their non-reducing ends. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| pectin catabolic process | The chemical reactions and pathways resulting in the breakdown of pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues. |
3 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q9M9S2 | AT59 | Probable pectate lyase 3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LRM5 | At3g24230 | Probable pectate lyase 9 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q944R1 | At4g13710 | Probable pectate lyase 15 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MVNLGSYVFV | FVALSLTVVV | PSVQAHIAEY | DEYWTQRQTN | ALRETLESYD | PNPENVTDHF |
| 70 | 80 | 90 | 100 | 110 | 120 |
| NYHAALAMET | TGIVNETRRD | LRQVGRGKKT | TRRGGRFESL | NAIDKCWRGD | KNWDKNRKKL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ADCVLGFGRK | TTGGKNGPIY | VVTDPSDNDL | LKPKPGTIRH | AVTRDRPLWI | IFARSMIIKL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| QQELIITNDK | TIDGRGAKIY | ITGGAGLTLQ | FVRNVIIHNI | HIKQIKRGAG | GLIIDSEQHF |
| 250 | 260 | 270 | 280 | 290 | 300 |
| GLRTVSDGDG | INIFGATNVW | IDHVSMTDCS | DGMIDAIMGS | TAITISNSHF | TDHDEVMLFG |
| 310 | 320 | 330 | 340 | 350 | 360 |
| GTNKDVIDKK | MQITVAFNHF | GKRLKQRMPR | VRFGLVHVVN | NDYTHWEMYA | IGGNMNPTII |
| 370 | 380 | 390 | 400 | 410 | 420 |
| SQGNRFIAPP | IEDSKQVTKR | EYTPYPEWKS | WNWQSEKDYF | LNGAYFVQSG | KANAWSATPK |
| 430 | 440 | 450 | |||
| NPIPRKFAIR | PQPGTKVRRL | TKDAGTLGCK | PGKSC |