Q9LQ27

PR
Gene name
TPS22
Protein name
Terpenoid synthase 22
Names
AtTPS22
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT1G33750
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

10-125 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9LQ27

Entry ID Method Resolution Chain Position Source
AF-Q9LQ27-F1 Predicted AlphaFoldDB

144 variants for Q9LQ27

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_1_12233782_G_T 5 R>I No 1000Genomes
tmp_1_12233786_G_C 6 M>I No 1000Genomes
ENSVATH01167937 6 M>T No 1000Genomes
ENSVATH04716755 7 G>V No 1000Genomes
ENSVATH01167938 9 R>G No 1000Genomes
tmp_1_12233822_C_G 18 N>K No 1000Genomes
ENSVATH04716757 19 G>S No 1000Genomes
ENSVATH00062636 21 R>Q No 1000Genomes
ENSVATH12761993 28 L>H No 1000Genomes
ENSVATH04716760 31 F>L No 1000Genomes
ENSVATH04716761 32 P>S No 1000Genomes
ENSVATH04716762 33 M>V No 1000Genomes
ENSVATH01167941 36 L>H No 1000Genomes
ENSVATH01167942 47 T>A No 1000Genomes
ENSVATH04716764 49 L>F No 1000Genomes
ENSVATH00062637 55 A>G No 1000Genomes
ENSVATH04716765 57 S>C No 1000Genomes
ENSVATH04716765 57 S>G No 1000Genomes
ENSVATH12761994 60 S>N No 1000Genomes
ENSVATH12761994 60 S>T No 1000Genomes
tmp_1_12233950_G_T,A,GTGT 61 G>D No 1000Genomes
tmp_1_12233950_G_T,A,GTGT 61 G>V No 1000Genomes
tmp_1_12233962_G_A 65 S>N No 1000Genomes
ENSVATH01167944 71 S>T No 1000Genomes
tmp_1_12233991_C_T 75 L>F No 1000Genomes
ENSVATH14059461 76 W>* No 1000Genomes
tmp_1_12234009_C_T 81 L>F No 1000Genomes
ENSVATH01167945 82 S>F No 1000Genomes
tmp_1_12234015_G_A 83 V>I No 1000Genomes
ENSVATH01167950 92 T>S No 1000Genomes
tmp_1_12234131_C_G 95 T>R No 1000Genomes
ENSVATH12762097 96 E>K No 1000Genomes
tmp_1_12234140_A_T 98 E>V No 1000Genomes
ENSVATH00062638 104 V>M No 1000Genomes
tmp_1_12234161_G_A 105 R>K No 1000Genomes
ENSVATH04716771 113 K>N No 1000Genomes
tmp_1_12234208_C_T 121 L>F No 1000Genomes
tmp_1_12234221_T_A 125 L>H No 1000Genomes
tmp_1_12234223_A_C 126 I>L No 1000Genomes
ENSVATH01167956 131 F>S No 1000Genomes
ENSVATH01167958 143 E>D No 1000Genomes
ENSVATH04716773 145 A>D No 1000Genomes
ENSVATH04716773 145 A>V No 1000Genomes
ENSVATH07547154 151 M>R No 1000Genomes
ENSVATH04716775 153 F>I No 1000Genomes
ENSVATH04716776 153 F>L No 1000Genomes
tmp_1_12234307_A_G 154 T>A No 1000Genomes
tmp_1_12234372_G_T 175 K>N No 1000Genomes
ENSVATH01167959 175 K>Q No 1000Genomes
tmp_1_12234525_G_A 186 G>S No 1000Genomes
tmp_1_12234549_C_T 194 H>Y No 1000Genomes
ENSVATH01167963 200 R>W No 1000Genomes
ENSVATH04716785 202 M>T No 1000Genomes
ENSVATH01167964 209 A>V No 1000Genomes
ENSVATH04716786 212 A>S No 1000Genomes
ENSVATH04716789 215 F>S No 1000Genomes
ENSVATH01167966 228 Y>* No 1000Genomes
ENSVATH00062639 231 E>A No 1000Genomes
ENSVATH04716792 242 H>N No 1000Genomes
ENSVATH01167967 242 H>P No 1000Genomes
ENSVATH04716792 242 H>Y No 1000Genomes
ENSVATH12762215 250 A>T No 1000Genomes
ENSVATH04716793 253 K>E No 1000Genomes
tmp_1_12234754_T_C 262 I>T No 1000Genomes
ENSVATH04716795 265 R>P No 1000Genomes
ENSVATH12762216 265 R>W No 1000Genomes
ENSVATH04716796 269 H>N No 1000Genomes
ENSVATH04716796 269 H>Y No 1000Genomes
ENSVATH14059463 277 D>G No 1000Genomes
tmp_1_12235306_A_G 310 D>G No 1000Genomes
ENSVATH00062640 312 P>A No 1000Genomes
tmp_1_12235315_A_G 313 Y>C No 1000Genomes
tmp_1_12235359_G_A 328 G>S No 1000Genomes
ENSVATH01167976 330 M>I No 1000Genomes
tmp_1_12235372_T_G 332 V>G No 1000Genomes
ENSVATH12762343 340 L>H No 1000Genomes
tmp_1_12235402_G_A 342 R>K No 1000Genomes
tmp_1_12235440_A_T 355 M>L No 1000Genomes
tmp_1_12235448_C_G 357 D>E No 1000Genomes
ENSVATH12762344 364 T>I No 1000Genomes
ENSVATH04716815 369 R>K No 1000Genomes
tmp_1_12235488_C_G 371 L>V No 1000Genomes
tmp_1_12235494_G_A 373 D>N No 1000Genomes
tmp_1_12235588_G_A 378 W>* No 1000Genomes
ENSVATH00062642 380 P>L No 1000Genomes
ENSVATH12762378 380 P>S No 1000Genomes
tmp_1_12235603_T_C 383 I>T No 1000Genomes
ENSVATH12762379 383 I>V No 1000Genomes
tmp_1_12235672_G_T 406 R>I No 1000Genomes
tmp_1_12235684_C_G 410 P>R No 1000Genomes
ENSVATH04716821 411 R>* No 1000Genomes
ENSVATH00062643 419 D>Y No 1000Genomes
ENSVATH04716822 423 E>D No 1000Genomes
tmp_1_12235807_T_A 424 I>N No 1000Genomes
ENSVATH04716829 424 I>V No 1000Genomes
tmp_1_12235833_G_A 433 E>K No 1000Genomes
ENSVATH00062644 434 I>T No 1000Genomes
ENSVATH00062645 440 A>V No 1000Genomes
tmp_1_12235863_G_A 443 V>I No 1000Genomes
tmp_1_12235867_C_T 444 P>L No 1000Genomes
ENSVATH00062647 452 L>V No 1000Genomes
tmp_1_12235918_G_T 461 C>F No 1000Genomes
ENSVATH01167982 469 S>A No 1000Genomes
ENSVATH01167984 474 E>G No 1000Genomes
ENSVATH01167985 476 N>S No 1000Genomes
ENSVATH01167986 477 Q>K No 1000Genomes
ENSVATH14059518 477 Q>P No 1000Genomes
tmp_1_12235975_C_A 480 A>E No 1000Genomes
ENSVATH12762445 484 S>F No 1000Genomes
ENSVATH12762446 499 T>K No 1000Genomes
ENSVATH12762446 499 T>R No 1000Genomes
ENSVATH04716834 504 G>S No 1000Genomes
ENSVATH12762447 510 R>W No 1000Genomes
ENSVATH04716835 517 G>R No 1000Genomes
ENSVATH00062650 520 C>S No 1000Genomes
tmp_1_12236099_C_G 521 Y>* No 1000Genomes
tmp_1_12236103_A_G 523 K>E No 1000Genomes
ENSVATH12762448 523 K>R No 1000Genomes
tmp_1_12236106_C_A 524 Q>K No 1000Genomes
tmp_1_12236110_A_G 525 H>R No 1000Genomes
ENSVATH00062652 526 N>S No 1000Genomes
tmp_1_12236128_T_A 531 L>* No 1000Genomes
ENSVATH12762449 534 R>G No 1000Genomes
ENSVATH12762450 534 R>Q No 1000Genomes
ENSVATH12762451 538 K>N No 1000Genomes
ENSVATH01167987 542 D>Y No 1000Genomes
ENSVATH12762452 543 N>S No 1000Genomes
ENSVATH12762453 547 M>L No 1000Genomes
tmp_1_12236181_G_A 549 E>K No 1000Genomes
tmp_1_12236198_A_G 554 I>M No 1000Genomes
ENSVATH12762454 555 K>E No 1000Genomes
tmp_1_12236200_A_T 555 K>I No 1000Genomes
ENSVATH00062653 556 S>C No 1000Genomes
ENSVATH00062653 556 S>G No 1000Genomes
tmp_1_12236208_TCACGTCCG_CCACGTCCG,T 558 S>P No 1000Genomes
tmp_1_12236215_C_T 560 P>L No 1000Genomes
ENSVATH12762505 566 F>L No 1000Genomes
ENSVATH12762505 566 F>V No 1000Genomes
ENSVATH14059519 581 N>H No 1000Genomes
ENSVATH00062655 582 F>Y No 1000Genomes
ENSVATH12762506 585 P>S No 1000Genomes
tmp_1_12236341_C_T 602 P>L No 1000Genomes
ENSVATH00062657 602 P>S No 1000Genomes
tmp_1_12236347_G_T 604 L>L No 1000Genomes

No associated diseases with Q9LQ27

3 regional properties for Q9LQ27

Type Name Position InterPro Accession
domain Terpene synthase, N-terminal domain 76 - 251 IPR001906
domain Terpene synthase, metal-binding domain 281 - 545 IPR005630
domain Terpene cyclase-like 1, C-terminal domain 277 - 601 IPR034741

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
cyclase activity Catalysis of a ring closure reaction.
magnesium ion binding Binding to a magnesium (Mg) ion.
terpene synthase activity Catalysis of the formation of cyclic terpenes through the cyclization of linear terpenes (e.g. isopentenyl-PP, geranyl-PP, farnesyl-PP and geranylgeranyl-PP) containing varying numbers of isoprene units.

3 GO annotations of biological process

Name Definition
diterpenoid biosynthetic process The chemical reactions and pathways resulting in the formation of diterpenoid compounds, terpenoids with four isoprene units.
sesquiterpene biosynthetic process The chemical reactions and pathways resulting in the formation of sesquiterpenes, any of a class of terpenes of the formula C15H24 or a derivative of such a terpene.
terpenoid biosynthetic process The chemical reactions and pathways resulting in the formation of terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure.

4 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
O23651 TPS01 Terpenoid synthase 1 Arabidopsis thaliana (Mouse-ear cress) PR
Q9C6W6 TPS29 Terpenoid synthase 29 Arabidopsis thaliana (Mouse-ear cress) PR
G5CV46 TPS31 Sesquiterpene synthase 31 Solanum lycopersicum (Tomato) (Lycopersicon esculentum) PR
G5CV45 TPS32 Viridiflorene synthase Solanum lycopersicum (Tomato) (Lycopersicon esculentum) PR
10 20 30 40 50 60
MEAARMGFRA KTLPHLGNGT RLPLKTKLSL FPMHLLQNHT TLSRRSTKLN LCVKACSKTS
70 80 90 100 110 120
GVESSRPLPH SAPDLWGDHI LSVPTENSEF DTLETEIESI KPKVRNMLMS SHKTDKERIC
130 140 150 160 170 180
LIHLLICLGT FHYFEKEIEE ILEQAFRKLD MLFTDEDDLE TTAIMFEVFR LYGHKISCDV
190 200 210 220 230 240
FDRFKGVDAK FKEHLVSDVR GMLQLYEAAH LATPFETILD EALSFTRYHL ESLAGQQATA
250 260 270 280 290 300
PHISRHILNA LYKPRFLKME IIAAREYIHF YQKEGHDETL LKFAKLNFNF CQLHYVRELK
310 320 330 340 350 360
TLTKWWKDID LPYKLPYIRD RLLETFIGVM AVYLEPHYSL GRIIATKVSQ VIVVMDDTCD
370 380 390 400 410 420
AYGTFSEVRS LIDSLERWDP GAIDKLPSCL RIVIQSIVET MEDIEREMKP RGRSSSVQDT
430 440 450 460 470 480
VEEIKIMGRA YAEISKWARA GHVPTFDDYI ELGLDSSGIR CFAMYSFISM EDCEENQTNA
490 500 510 520 530 540
WFKSKPKMLR ALSVIFRLTN DIAGFEEEMR RGEVVNGVNC YVKQHNVTKE LAVREIKKMI
550 560 570 580 590 600
RDNYKIMMEE FLTIKSVSRP ILVRCFNIVR LVNLYYEEGD NFTNPNGKLK DLITSLFFHP
LPL