Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9C6W6

Entry ID Method Resolution Chain Position Source
AF-Q9C6W6-F1 Predicted AlphaFoldDB

97 variants for Q9C6W6

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH00057220 8 F>I No 1000Genomes
tmp_1_11475847_A_G 14 H>R No 1000Genomes
ENSVATH04696082 16 V>I No 1000Genomes
ENSVATH04696083 19 C>R No 1000Genomes
ENSVATH01148142 23 T>S No 1000Genomes
tmp_1_11475882_C_A 26 L>I No 1000Genomes
tmp_1_11475888_C_A 28 P>T No 1000Genomes
ENSVATH04696084 41 K>R No 1000Genomes
ENSVATH14035338 43 A>T No 1000Genomes
tmp_1_11475939_C_G 45 Q>E No 1000Genomes
tmp_1_11475949_T_G 48 F>C No 1000Genomes
tmp_1_11475948_T_C 48 F>L No 1000Genomes
ENSVATH00057221 49 F>L No 1000Genomes
tmp_1_11475955_T_A 50 V>D No 1000Genomes
tmp_1_11475970_A_C 55 K>T No 1000Genomes
ENSVATH12582130 57 S>N No 1000Genomes
ENSVATH04696086 62 E>D No 1000Genomes
tmp_1_11475997_G_T 64 S>I No 1000Genomes
tmp_1_11476030_G_T 75 W>L No 1000Genomes
tmp_1_11476053_T_G 83 S>A No 1000Genomes
ENSVATH01148143 85 N>D No 1000Genomes
tmp_1_11476160_G_C 88 E>D No 1000Genomes
ENSVATH01148147 111 E>Q No 1000Genomes
ENSVATH04696091 112 S>R No 1000Genomes
ENSVATH12582134 119 R>H No 1000Genomes
tmp_1_11476282_T_C 129 I>T No 1000Genomes
ENSVATH01148149 131 Y>N No 1000Genomes
tmp_1_11476292_T_A 132 H>Q No 1000Genomes
ENSVATH12582235 135 K>E No 1000Genomes
ENSVATH01148150 139 D>E No 1000Genomes
ENSVATH04696094 143 H>R No 1000Genomes
tmp_1_11476341_G_A 149 D>N No 1000Genomes
tmp_1_11476346_C_G 150 D>E No 1000Genomes
ENSVATH00057224 152 I>T No 1000Genomes
ENSVATH01148152 169 K>R No 1000Genomes
ENSVATH14035339 172 G>A No 1000Genomes
ENSVATH14035339 172 G>V No 1000Genomes
tmp_1_11476428_G_C 178 D>H No 1000Genomes
ENSVATH14035340 180 F>Y No 1000Genomes
ENSVATH14035341 191 K>E No 1000Genomes
tmp_1_11476636_G_A 214 C>Y No 1000Genomes
ENSVATH14035342 238 S>F No 1000Genomes
tmp_1_11476714_C_G 240 A>G No 1000Genomes
tmp_1_11476719_C_T 242 P>S No 1000Genomes
tmp_1_11476726_T_A 244 L>H No 1000Genomes
ENSVATH04696102 245 L>M No 1000Genomes
ENSVATH12582243 254 I>V No 1000Genomes
ENSVATH01148157 279 D>E No 1000Genomes
tmp_1_11476837_TC_AC,T 281 I>N No 1000Genomes
ENSVATH07540460 292 F>L No 1000Genomes
ENSVATH12582244 296 H>R No 1000Genomes
tmp_1_11476911_A_C 306 K>Q No 1000Genomes
ENSVATH01148162 309 R>T No 1000Genomes
ENSVATH04696108 313 L>I No 1000Genomes
ENSVATH14035344 318 P>L No 1000Genomes
ENSVATH04696109 321 R>W No 1000Genomes
tmp_1_11477073_G_A 330 V>M No 1000Genomes
tmp_1_11477109_C_T 342 L>F No 1000Genomes
ENSVATH14035385 357 V>M No 1000Genomes
tmp_1_11477178_G_C 365 A>P No 1000Genomes
ENSVATH01148164 369 Q>E No 1000Genomes
ENSVATH12582336 371 K>E No 1000Genomes
ENSVATH04696113 378 Q>H No 1000Genomes
ENSVATH04696119 397 G>R No 1000Genomes
ENSVATH04696120 401 D>A No 1000Genomes
tmp_1_11477385_G_T 405 E>D No 1000Genomes
ENSVATH07540470 408 R>Q No 1000Genomes
ENSVATH04696122 409 E>K No 1000Genomes
ENSVATH04696122 409 E>Q No 1000Genomes
tmp_1_11477400_G_A 410 M>I No 1000Genomes
ENSVATH12582340 410 M>V No 1000Genomes
tmp_1_11477404_C_T 412 P>S No 1000Genomes
ENSVATH14035386 421 Q>L No 1000Genomes
ENSVATH04696124 422 V>E No 1000Genomes
ENSVATH12582395 432 A>V No 1000Genomes
ENSVATH00057234 434 Q>L No 1000Genomes
tmp_1_11477632_T_C 451 Y>H No 1000Genomes
tmp_1_11477654_C_G 458 T>R No 1000Genomes
ENSVATH00057236 462 A>G No 1000Genomes
ENSVATH01148172 478 K>E No 1000Genomes
tmp_1_11477792_T_C 504 V>A No 1000Genomes
tmp_1_11477791_G_A 504 V>I No 1000Genomes
tmp_1_11477909_A_C 513 R>S No 1000Genomes
tmp_1_11477950_A_G 527 Y>C No 1000Genomes
ENSVATH04696131 530 T>S No 1000Genomes
tmp_1_11477974_C_T 535 S>F No 1000Genomes
ENSVATH12582400 536 R>L No 1000Genomes
tmp_1_11477996_C_G 542 Y>* No 1000Genomes
ENSVATH04696133 545 R>H No 1000Genomes
tmp_1_11478003_C_A 545 R>S No 1000Genomes
ENSVATH01148178 549 V>F No 1000Genomes
ENSVATH04696134 558 D>H No 1000Genomes
tmp_1_11478084_G_A 572 A>T No 1000Genomes
ENSVATH14035391 587 E>A No 1000Genomes
ENSVATH14035392 587 E>D No 1000Genomes
ENSVATH01148179 605 P>L No 1000Genomes
ENSVATH01148179 605 P>R No 1000Genomes

No associated diseases with Q9C6W6

3 regional properties for Q9C6W6

Type Name Position InterPro Accession
domain Terpene synthase, N-terminal domain 75 - 252 IPR001906
domain Terpene synthase, metal-binding domain 283 - 544 IPR005630
domain Terpene cyclase-like 1, C-terminal domain 280 - 604 IPR034741

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
cyclase activity Catalysis of a ring closure reaction.
magnesium ion binding Binding to a magnesium (Mg) ion.
terpene synthase activity Catalysis of the formation of cyclic terpenes through the cyclization of linear terpenes (e.g. isopentenyl-PP, geranyl-PP, farnesyl-PP and geranylgeranyl-PP) containing varying numbers of isoprene units.

2 GO annotations of biological process

Name Definition
diterpenoid biosynthetic process The chemical reactions and pathways resulting in the formation of diterpenoid compounds, terpenoids with four isoprene units.
sesquiterpene biosynthetic process The chemical reactions and pathways resulting in the formation of sesquiterpenes, any of a class of terpenes of the formula C15H24 or a derivative of such a terpene.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9LQ27 TPS22 Terpenoid synthase 22 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MEAIRIGFGL PNVHSVPLCL TTTRCLFPRQ RLLHSHTPSW KPAKQQDFFV ASSSKKSSDD
70 80 90 100 110 120
LESSLPTPHF SPSLWGDHFL SVSLNRAEFD ELEREIETTK PLARDKLMSS ESSDKEKIRL
130 140 150 160 170 180
IHLLVSMGIS YHFDKEIQDI LKHSFTKLDD IIVGEDDLET ISIMFEVFKL YGHKMSCDAF
190 200 210 220 230 240
DRFRGNDGRF KESLVRDFRG MLQLFEVAHL GTPCEVIMDE ALSFTRNHLE SLTSGNASTA
250 260 270 280 290 300
SPHLLKHIQN SLYIPRYCNI EVLVAREYIS YYEQEEGHDE ILLKFAKLNF NFCQFHYVQE
310 320 330 340 350 360
LKTLTKWWRD LDLASKLPYI RDRLVESHLV ALGPYFEPHY SLGRIIVAKI NMIMVVVDDT
370 380 390 400 410 420
YDAYATLPQV KALTECLQRW SIEVSDKLPD YLRIVLGSLF DVMGEIEREM RPLGRLYRVK
430 440 450 460 470 480
QVVEKIKIIT KAYQEIAKWA RTGHVSTFDE YMKVGVLTAG MADYAAYCFI GMEDINEKEA
490 500 510 520 530 540
FEWLNSNPLI IKHLTAMFRL ANDVGTYETE INRGEVANGL NCYMKQYGVT KEEASRELRK
550 560 570 580 590 600
MYVYRKKVVV EEFMNSHDHV PRQVLLRCLN IARIFDVFYT EGDGYSEPKG KIEHFMTSLY
LHPIPLS