Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for G5CV45

Entry ID Method Resolution Chain Position Source
AF-G5CV45-F1 Predicted AlphaFoldDB

No variants for G5CV45

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for G5CV45

No associated diseases with G5CV45

3 regional properties for G5CV45

Type Name Position InterPro Accession
domain Terpene synthase, N-terminal domain 22 - 195 IPR001906
domain Terpene synthase, metal-binding domain 226 - 490 IPR005630
domain Terpene cyclase-like 1, C-terminal domain 221 - 547 IPR034741

Functions

Description
EC Number 4.2.3.88 Acting on phosphates
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
carbon-oxygen lyase activity, acting on phosphates Catalysis of the cleavage of a carbon-oxygen bond by elimination of a phosphate.
magnesium ion binding Binding to a magnesium (Mg) ion.
sesquiterpene synthase activity Catalysis of the reaction: trans,trans-farnesyl diphosphate = a sesquiterpene + diphosphate. Sesquiterpenes are terpenes containing three isoprene units, i.e. 15 carbons.

3 GO annotations of biological process

Name Definition
diterpenoid biosynthetic process The chemical reactions and pathways resulting in the formation of diterpenoid compounds, terpenoids with four isoprene units.
farnesyl diphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of farnesyl diphosphate.
sesquiterpene biosynthetic process The chemical reactions and pathways resulting in the formation of sesquiterpenes, any of a class of terpenes of the formula C15H24 or a derivative of such a terpene.

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9LQ27 TPS22 Terpenoid synthase 22 Arabidopsis thaliana (Mouse-ear cress) PR
O23651 TPS01 Terpenoid synthase 1 Arabidopsis thaliana (Mouse-ear cress) PR
G5CV46 TPS31 Sesquiterpene synthase 31 Solanum lycopersicum (Tomato) (Lycopersicon esculentum) PR
10 20 30 40 50 60
MALLNNQDEI VRPVANFSPS LWGDRFHSFS LDNQVADKYA QQIETLKEQT RSLLSDAACG
70 80 90 100 110 120
TTLAEKLNLI DIVERLGLAY HFEKQIEDML DQIYKADPNF EAHDLNTLSL QFRILRQHGY
130 140 150 160 170 180
NISQKIFSRF QDANGKFKES LSNDIKGLLN LYEASHVRTH GEDILEEALA FSTAHLESAA
190 200 210 220 230 240
PHLKSPLSKQ VTHALEQSLH KSIPRVETRY FISIYEEEEF KNDVLLRFAK LDYNLLQMLH
250 260 270 280 290 300
KQELSEVSRW WKDLDFVTTL PYARDRAVEC YFWTMGVYAE PQYSQARVML AKTIAMISIV
310 320 330 340 350 360
DDTFDAYGIV KELEVYTDAI QRWDISQMDR LPEYMKVSFK ALLDLYEDYE KELSKDGRSD
370 380 390 400 410 420
VVQYAKERMK EIVRNYFVEA KWFIEGYMPP VSEYLSNALA TSTYYLLTTT SYLGVKSATK
430 440 450 460 470 480
EDFEWLAKNP KILEANVTLC RVVDDIATYE VEKGRGQIAT GIECYMRDYG VSTQVAMDKF
490 500 510 520 530 540
QEMAEIAWKD VNEGILRPTP VSTEILTRIL NLARIIDVTY KHNQDGYTHP EKVLKPHIIA
LLVDSIEI