Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for O23651

Entry ID Method Resolution Chain Position Source
AF-O23651-F1 Predicted AlphaFoldDB

183 variants for O23651

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH06682037 2 Y>C No 1000Genomes
tmp_4_9010936_T_C 4 I>M No 1000Genomes
ENSVATH02847274 6 L>Q No 1000Genomes
tmp_4_9010926_C_G 8 V>L No 1000Genomes
tmp_4_9010922_T_A 9 N>I No 1000Genomes
tmp_4_9010907_G_A,GATAT 14 S>L No 1000Genomes
ENSVATH11813849 17 G>* No 1000Genomes
tmp_4_9010891_T_C 19 I>M No 1000Genomes
ENSVATH06682036 20 L>R No 1000Genomes
tmp_4_9010876_T_A 24 L>F No 1000Genomes
tmp_4_9010865_A_C 28 L>* No 1000Genomes
tmp_4_9010835_G_T 38 P>H No 1000Genomes
tmp_4_9010830_T_G 40 K>Q No 1000Genomes
ENSVATH11813846 45 Q>H No 1000Genomes
tmp_4_9010805_T_C 48 K>R No 1000Genomes
tmp_4_9010793_A_G 52 M>T No 1000Genomes
ENSVATH02847273 56 P>H No 1000Genomes
ENSVATH14209208 57 T>I No 1000Genomes
ENSVATH00509632 59 A>D No 1000Genomes
ENSVATH00509632 59 A>G No 1000Genomes
tmp_4_9010761_G_A 63 Q>* No 1000Genomes
tmp_4_9010760_T_A 63 Q>L No 1000Genomes
ENSVATH00509631 66 N>K No 1000Genomes
ENSVATH06682035 66 N>S No 1000Genomes
ENSVATH14209207 69 F>L No 1000Genomes
ENSVATH02847272 72 L>V No 1000Genomes
tmp_4_9010721_T_G 76 K>T No 1000Genomes
ENSVATH14209206 78 G>C No 1000Genomes
ENSVATH14209205 79 H>Q No 1000Genomes
ENSVATH11813804 86 V>F No 1000Genomes
tmp_4_9010687_A_T 87 D>E No 1000Genomes
ENSVATH06682032 94 L>F No 1000Genomes
ENSVATH06682032 94 L>I No 1000Genomes
ENSVATH14209193 95 A>S No 1000Genomes
tmp_4_9010576_GC_AC,G 95 A>V No 1000Genomes
ENSVATH06682030 99 E>K No 1000Genomes
ENSVATH00509628 101 L>I No 1000Genomes
ENSVATH11813798 103 P>L No 1000Genomes
tmp_4_9010550_C_T 104 E>K No 1000Genomes
ENSVATH14209192 107 E>Q No 1000Genomes
ENSVATH02847261 111 F>L No 1000Genomes
ENSVATH11813796 115 S>N No 1000Genomes
ENSVATH14209191 118 S>P No 1000Genomes
tmp_4_9010504_G_A 119 T>I No 1000Genomes
ENSVATH00509627 121 K>T No 1000Genomes
ENSVATH06682028 123 I>V No 1000Genomes
ENSVATH06682027 124 L>I No 1000Genomes
ENSVATH06682026 126 I>R No 1000Genomes
ENSVATH11813795 134 V>I No 1000Genomes
ENSVATH00509625 144 Q>E No 1000Genomes
tmp_4_9010426_C_A 145 S>I No 1000Genomes
ENSVATH11813754 148 E>Q No 1000Genomes
tmp_4_9010402_A_C 153 I>R No 1000Genomes
ENSVATH11813753 155 E>D No 1000Genomes
tmp_4_9010393_A_G 156 M>T No 1000Genomes
ENSVATH14209190 164 Y>F No 1000Genomes
ENSVATH00509624 165 T>A No 1000Genomes
ENSVATH00509624 165 T>S No 1000Genomes
tmp_4_9010234_A_T 184 V>D No 1000Genomes
ENSVATH06682019 184 V>I No 1000Genomes
ENSVATH11813746 187 R>K No 1000Genomes
ENSVATH11813745 188 F>S No 1000Genomes
ENSVATH02847253 190 G>E No 1000Genomes
ENSVATH06682018 194 K>N No 1000Genomes
ENSVATH06682017 196 M>L No 1000Genomes
ENSVATH14209188 196 M>T No 1000Genomes
tmp_4_9010190_T_G 199 I>L No 1000Genomes
tmp_4_9010189_A_C 199 I>R No 1000Genomes
ENSVATH02847252 200 T>I No 1000Genomes
ENSVATH02847251 201 S>G No 1000Genomes
ENSVATH11813704 204 K>R No 1000Genomes
tmp_4_9010166_C_T 207 V>M No 1000Genomes
ENSVATH00509621 213 A>S No 1000Genomes
ENSVATH00509620 213 A>V No 1000Genomes
ENSVATH14209187 222 I>M No 1000Genomes
ENSVATH02847250 230 T>N No 1000Genomes
ENSVATH11813703 230 T>S No 1000Genomes
tmp_4_9010090_C_G 232 R>T No 1000Genomes
ENSVATH14209186 236 S>* No 1000Genomes
ENSVATH00509618 237 L>F No 1000Genomes
ENSVATH06682016 240 A>T No 1000Genomes
ENSVATH14209185 241 G>R No 1000Genomes
tmp_4_9010060_G_A 242 A>V No 1000Genomes
ENSVATH00509617 243 S>G No 1000Genomes
ENSVATH06682013 245 P>L No 1000Genomes
ENSVATH06682014 245 P>T No 1000Genomes
ENSVATH02847249 246 H>Q No 1000Genomes
tmp_4_9010046_T_A 247 I>F No 1000Genomes
tmp_4_9010042_A_C 248 L>* No 1000Genomes
ENSVATH06682012 250 R>H No 1000Genomes
tmp_4_9010033_A_T 251 I>K No 1000Genomes
ENSVATH06682011 251 I>V No 1000Genomes
ENSVATH06682010 255 L>V No 1000Genomes
ENSVATH11813702 256 C>R No 1000Genomes
ENSVATH02847248 256 C>Y No 1000Genomes
ENSVATH06682009 257 M>I No 1000Genomes
ENSVATH00509615 258 P>H No 1000Genomes
ENSVATH00509614 264 E>K No 1000Genomes
ENSVATH11813701 267 F>S No 1000Genomes
ENSVATH11813700 268 A>P No 1000Genomes
ENSVATH02847245 269 R>K No 1000Genomes
ENSVATH02847245 269 R>T No 1000Genomes
ENSVATH11813696 274 F>L No 1000Genomes
tmp_4_9009958_T_A 276 E>V No 1000Genomes
ENSVATH02847244 277 Q>R No 1000Genomes
tmp_4_9009933_C_T 284 M>I No 1000Genomes
ENSVATH00509613 284 M>L No 1000Genomes
ENSVATH06682007 297 Q>R No 1000Genomes
ENSVATH06682006 301 I>S No 1000Genomes
ENSVATH11813663 313 Q>E No 1000Genomes
ENSVATH14209122 324 F>Y No 1000Genomes
ENSVATH02847238 336 I>L No 1000Genomes
ENSVATH11813662 343 Q>E No 1000Genomes
ENSVATH02847237 344 F>I No 1000Genomes
ENSVATH00509612 348 R>K No 1000Genomes
ENSVATH02847235 359 T>S No 1000Genomes
tmp_4_9009621_C_A 361 V>F No 1000Genomes
ENSVATH02847234 365 C>Y No 1000Genomes
tmp_4_9009598_G_C 368 Y>* No 1000Genomes
tmp_4_9009597_C_T 369 G>S No 1000Genomes
ENSVATH06682005 370 N>Y No 1000Genomes
ENSVATH06682004 373 E>D No 1000Genomes
tmp_4_9009578_G_A 375 A>V No 1000Genomes
ENSVATH02847233 379 Q>* No 1000Genomes
ENSVATH02847233 379 Q>E No 1000Genomes
tmp_4_9009236_C_T 384 W>* No 1000Genomes
ENSVATH00509610 389 M>T No 1000Genomes
ENSVATH06681991 389 M>V No 1000Genomes
tmp_4_9009217_G_T 390 D>E No 1000Genomes
ENSVATH06681990 390 D>G No 1000Genomes
tmp_4_9009219_C_T 390 D>N No 1000Genomes
tmp_4_9009205_A_C 394 D>E No 1000Genomes
tmp_4_9009203_T_G 395 Y>S No 1000Genomes
ENSVATH06681989 399 V>L No 1000Genomes
ENSVATH02847229 404 W>* No 1000Genomes
ENSVATH15362735 410 C>* No 1000Genomes
tmp_4_9009110_C_T 426 G>D No 1000Genomes
ENSVATH06681983 443 Y>C No 1000Genomes
ENSVATH11813572 445 E>K No 1000Genomes
tmp_4_9008921_A_C 446 I>S No 1000Genomes
tmp_4_9008915_C_T 448 G>E No 1000Genomes
ENSVATH06681981 453 M>I No 1000Genomes
ENSVATH14209118 455 V>I No 1000Genomes
tmp_4_9008866_C_G 464 L>F No 1000Genomes
tmp_4_9008850_C_G 470 E>Q No 1000Genomes
tmp_4_9008843_G_A 472 A>V No 1000Genomes
ENSVATH11813571 473 Y>F No 1000Genomes
ENSVATH00509607 473 Y>N No 1000Genomes
ENSVATH00509606 476 L>R No 1000Genomes
tmp_4_9008829_T_C 477 K>E No 1000Genomes
tmp_4_9008827_T_A 477 K>N No 1000Genomes
ENSVATH00509605 481 K>N No 1000Genomes
ENSVATH00509604 483 V>I No 1000Genomes
ENSVATH00509603 488 K>N No 1000Genomes
tmp_4_9008792_C_T 489 R>K No 1000Genomes
tmp_4_9008789_G_C 490 A>G No 1000Genomes
ENSVATH14209117 491 R>C No 1000Genomes
ENSVATH00509602 493 M>K No 1000Genomes
ENSVATH06681980 497 A>D No 1000Genomes
ENSVATH06681979 498 G>D No 1000Genomes
tmp_4_9008762_A_G 499 F>S No 1000Genomes
tmp_4_9008653_C_T 506 G>R No 1000Genomes
tmp_4_9008638_C_G 511 A>P No 1000Genomes
ENSVATH02847224 518 Q>K No 1000Genomes
tmp_4_9008587_T_C 528 T>A No 1000Genomes
ENSVATH06681974 530 L>V No 1000Genomes
tmp_4_9008578_G_C 531 Q>E No 1000Genomes
tmp_4_9008574_T_A 532 K>M No 1000Genomes
tmp_4_9008562_T_C 536 D>G No 1000Genomes
tmp_4_9008550_G_A 540 T>I No 1000Genomes
ENSVATH00509601 544 E>K No 1000Genomes
ENSVATH06681973 548 T>I No 1000Genomes
ENSVATH11813566 549 T>R No 1000Genomes
tmp_4_9008494_G_A 559 R>W No 1000Genomes
ENSVATH00509600 560 A>T No 1000Genomes
tmp_4_9008479_C_A 564 G>* No 1000Genomes
ENSVATH14209115 564 G>E No 1000Genomes
ENSVATH11813565 573 S>F No 1000Genomes
ENSVATH11813542 579 H>Y No 1000Genomes
ENSVATH14209103 585 K>M No 1000Genomes
tmp_4_9008409_T_C 587 H>R No 1000Genomes
ENSVATH06681972 587 H>Y No 1000Genomes
ENSVATH11813541 596 I>V No 1000Genomes

No associated diseases with O23651

No regional properties for O23651

Type Name Position InterPro Accession
No domain, repeats, and functional sites for O23651

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
cyclase activity Catalysis of a ring closure reaction.
magnesium ion binding Binding to a magnesium (Mg) ion.
terpene synthase activity Catalysis of the formation of cyclic terpenes through the cyclization of linear terpenes (e.g. isopentenyl-PP, geranyl-PP, farnesyl-PP and geranylgeranyl-PP) containing varying numbers of isoprene units.

3 GO annotations of biological process

Name Definition
diterpenoid biosynthetic process The chemical reactions and pathways resulting in the formation of diterpenoid compounds, terpenoids with four isoprene units.
sesquiterpene biosynthetic process The chemical reactions and pathways resulting in the formation of sesquiterpenes, any of a class of terpenes of the formula C15H24 or a derivative of such a terpene.
terpene biosynthetic process The chemical reactions and pathways resulting in the formation of terpenes, any of a large group of hydrocarbons made up of isoprene units.

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9LQ27 TPS22 Terpenoid synthase 22 Arabidopsis thaliana (Mouse-ear cress) PR
G5CV46 TPS31 Sesquiterpene synthase 31 Solanum lycopersicum (Tomato) (Lycopersicon esculentum) PR
G5CV45 TPS32 Viridiflorene synthase Solanum lycopersicum (Tomato) (Lycopersicon esculentum) PR
10 20 30 40 50 60
MYSISLVVNM QCISAYGSIL SLPLRSNLFS VRKLSSFPHK SFSGQHGKLV RMKATPTRAC
70 80 90 100 110 120
HDQESNRKFK RLPLSKWGHH FLSAQVDVSE MNALAQEIER LKPEVGEMLM FSSKSIESTK
130 140 150 160 170 180
KRILFIYMLV SLGVAFHFED EIEQSLEEGF EKIQEMIAGE DDLYTISIMF WVFRTYGYNM
190 200 210 220 230 240
STDVFKRFKG ENEKFMESIT SDVKGMVSLY EAAHLRTTRE DILEEALSFT TRNLESLARA
250 260 270 280 290 300
GASSPHILMR IRNALCMPQH YNAEMIFARE YISFYEQEED HNKMLLRFAK INFKFLQLNW
310 320 330 340 350 360
IQELKTLTKW WKQQDLASKL PPYFRDRLIE CYLFAIMIYF EPQFSLGRVS LAKINTVFTL
370 380 390 400 410 420
VDDTCDRYGN VSEVAALVQC VERWDPDCMD SLPDYMKTVF KFAWNTFEEC ENAGIMEEGL
430 440 450 460 470 480
SYDVQGALEE WEQGDVVPTF DEYLEIGGVE VTMYVSIACS FLGLGQSSRE QAYKWLKSRP
490 500 510 520 530 540
KFVEAQAKRA RLMNDIAGFE GDMSRGFDVN AIMYYMKQYK VTEEETFTRL QKMARDLDTT
550 560 570 580 590
VNEEILKTTK SVPRQILKRA IDFGKMIEFT YRSGEEYTHP EGRFKDHITS LFVDLIRL