Q9LJL4

PR
Gene name
IPT8 (PGA22, At3g19160, MVI11.16)
Protein name
Adenylate isopentenyltransferase 8, chloroplastic
Names
AtIPT8, Adenylate dimethylallyltransferase 8, Cytokinin synthase 8, Plant growth activator 22
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT3G19160
EC number
2.5.1.112: Transferring alkyl or aryl groups, other than methyl groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-67 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9LJL4

Entry ID Method Resolution Chain Position Source
AF-Q9LJL4-F1 Predicted AlphaFoldDB

56 variants for Q9LJL4

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH05861423 16 I>T No 1000Genomes
ENSVATH02164286 17 T>I No 1000Genomes
ENSVATH02164285 24 P>S No 1000Genomes
ENSVATH00333551 40 S>L No 1000Genomes
ENSVATH02164283 58 C>R No 1000Genomes
ENSVATH13945848 69 G>S No 1000Genomes
ENSVATH05861422 72 V>I No 1000Genomes
ENSVATH10776997 76 K>T No 1000Genomes
ENSVATH00333550 81 D>N No 1000Genomes
ENSVATH13945847 89 Q>L No 1000Genomes
ENSVATH00333549 96 C>R No 1000Genomes
tmp_3_6622924_C_T 105 E>K No 1000Genomes
ENSVATH05861421 108 P>L No 1000Genomes
tmp_3_6622915_G_T 108 P>T No 1000Genomes
ENSVATH02164282 110 D>E No 1000Genomes
ENSVATH05861420 110 D>G No 1000Genomes
ENSVATH00333547 111 S>G No 1000Genomes
ENSVATH02164281 112 E>K No 1000Genomes
ENSVATH00333546 114 T>S No 1000Genomes
tmp_3_6622882_G_A 119 R>C No 1000Genomes
ENSVATH02164280 121 L>F No 1000Genomes
ENSVATH02164278 124 R>L No 1000Genomes
ENSVATH00333543 134 N>K No 1000Genomes
ENSVATH05861418 143 N>K No 1000Genomes
ENSVATH00333541 165 T>A No 1000Genomes
ENSVATH02164276 168 S>C No 1000Genomes
ENSVATH10776949 180 V>M No 1000Genomes
ENSVATH00333538 194 R>L No 1000Genomes
ENSVATH05861407 199 M>V No 1000Genomes
tmp_3_6622373_C_T 205 E>K No 1000Genomes
ENSVATH05861405 208 A>V No 1000Genomes
ENSVATH05861404 209 G>D No 1000Genomes
tmp_3_6622355_A_G 211 Y>H No 1000Genomes
tmp_3_6622349_G_A 213 P>S No 1000Genomes
ENSVATH10776948 221 R>* No 1000Genomes
ENSVATH00333537 222 A>T No 1000Genomes
ENSVATH00333536 236 R>G No 1000Genomes
tmp_3_6622276_T_G 237 Y>S No 1000Genomes
ENSVATH05861403 242 P>S No 1000Genomes
ENSVATH02164265 247 Q>H No 1000Genomes
tmp_3_6622229_C_T 253 D>N No 1000Genomes
ENSVATH00333535 254 Q>E No 1000Genomes
ENSVATH02164264 258 G>A No 1000Genomes
tmp_3_6622202_C_T 262 E>K No 1000Genomes
ENSVATH05861400 262 E>V No 1000Genomes
tmp_3_6622196_C_A 264 V>F No 1000Genomes
tmp_3_6622153_T_G 278 Q>P No 1000Genomes
tmp_3_6622127_T_C 287 S>G No 1000Genomes
tmp_3_6622082_C_T 302 G>R No 1000Genomes
tmp_3_6622078_C_G 303 R>T No 1000Genomes
ENSVATH10776947 310 D>E No 1000Genomes
ENSVATH00333533 311 N>K No 1000Genomes
ENSVATH10776945 319 K>N No 1000Genomes
ENSVATH10776924 326 V>A No 1000Genomes
ENSVATH02164263 329 K>E No 1000Genomes
tmp_3_6621997_A_G 330 V>A No 1000Genomes

No associated diseases with Q9LJL4

No regional properties for Q9LJL4

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q9LJL4

Functions

Description
EC Number 2.5.1.112 Transferring alkyl or aryl groups, other than methyl groups
Subcellular Localization
  • Plastid, chloroplast
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
chloroplast A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

5 GO annotations of molecular function

Name Definition
ADP dimethylallyltransferase activity Catalysis of the reaction: delta2-isopentenyl diphosphate + ADP = diphosphate + N6-(delta(2)-isopentenyl)adenosine 5'-diphosphate.
AMP dimethylallyltransferase activity Catalysis of the reaction: AMP + dimethylallyl diphosphate = N(6)-(dimethylallyl)adenosine 5'-phosphate + diphosphate.
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP dimethylallyltransferase activity Catalysis of the reaction: delta(2)-isopentenyl diphosphate + ATP = diphosphate + N6-(delta(2)-isopentenyl)adenosine 5'-triphosphate.
tRNA dimethylallyltransferase activity Catalysis of the reaction: dimethylallyl diphosphate + tRNA = diphosphate + tRNA containing 6-dimethylallyladenosine.

2 GO annotations of biological process

Name Definition
cytokinin biosynthetic process The chemical reactions and pathways resulting in the formation of cytokinins, a class of adenine-derived compounds that can function in plants as growth regulators.
tRNA modification The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically.

4 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P16384 miaA tRNA dimethylallyltransferase Escherichia coli (strain K12) PR
Q9H3H1 TRIT1 tRNA dimethylallyltransferase Homo sapiens (Human) PR
Q80UN9 Trit1 tRNA dimethylallyltransferase Mus musculus (Mouse) PR
Q93WC9 IPT3 Adenylate isopentenyltransferase 3, chloroplastic Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MQNLTSTFVS PSMIPITSPR LRLPPPRSVV PMTTVCMEQS YKQKVVVIMG ATGSGKSCLS
70 80 90 100 110 120
IDLATRFSGE IVNSDKIQFY DGLKVTTNQM SILERCGVPH HLLGELPPDD SELTTSEFRS
130 140 150 160 170 180
LASRSISEIT ARGNLPIIAG GSNSFIHALL VDRFDPKTYP FSSETSISSG LRYECCFLWV
190 200 210 220 230 240
DVSVSVLFEY LSKRVDQMME SGMFEELAGF YDPRYSGSAI RAHGIHKTIG IPEFDRYFSL
250 260 270 280 290 300
YPPERKQKMS EWDQARKGAY DEAVQEIKEN TWRLAKKQIE RIMKLKSSGW DIQRLDATPS
310 320
FGRSSREIWD NTVLDESIKV VKRFLVKDKV