Q93WC9
Gene name |
IPT3 (At3g63110, T20O10.210) |
Protein name |
Adenylate isopentenyltransferase 3, chloroplastic |
Names |
AtIPT3, Adenylate dimethylallyltransferase 3, Cytokinin synthase 3 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT3G63110 |
EC number |
2.5.1.112: Transferring alkyl or aryl groups, other than methyl groups |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q93WC9
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q93WC9-F1 | Predicted | AlphaFoldDB |
20 variants for Q93WC9
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_3_23319392_G_A | 19 | T>I | No | 1000Genomes | |
| ENSVATH06363984 | 29 | P>S | No | 1000Genomes | |
| ENSVATH14472723 | 45 | V>I | No | 1000Genomes | |
| ENSVATH06363980 | 90 | S>R | No | 1000Genomes | |
| tmp_3_23319162_C_T | 96 | V>I | No | 1000Genomes | |
| ENSVATH06363979 | 114 | N>I | No | 1000Genomes | |
| tmp_3_23319098_T_C | 117 | H>R | No | 1000Genomes | |
| tmp_3_23319063_G_T | 129 | R>S | No | 1000Genomes | |
| tmp_3_23318989_C_A | 153 | K>N | No | 1000Genomes | |
| ENSVATH06363978 | 173 | H>N | No | 1000Genomes | |
| tmp_3_23318892_T_C | 186 | S>G | No | 1000Genomes | |
| ENSVATH12894770 | 195 | F>V | No | 1000Genomes | |
| ENSVATH14472721 | 195 | F>Y | No | 1000Genomes | |
| ENSVATH06363977 | 201 | S>F | No | 1000Genomes | |
| ENSVATH14472719 | 261 | R>I | No | 1000Genomes | |
| tmp_3_23318625_G_T | 275 | P>T | No | 1000Genomes | |
| ENSVATH02539169 | 282 | S>Y | No | 1000Genomes | |
| tmp_3_23318600_T_A | 283 | K>M | No | 1000Genomes | |
| ENSVATH12894768 | 284 | M>I | No | 1000Genomes | |
| ENSVATH06363973 | 321 | A>T | No | 1000Genomes |
No associated diseases with Q93WC9
No regional properties for Q93WC9
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q93WC9 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 2.5.1.112 | Transferring alkyl or aryl groups, other than methyl groups |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
5 GO annotations of cellular component
| Name | Definition |
|---|---|
| chloroplast | A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma. |
| mitochondrion | A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. |
| nuclear membrane | Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
| plastid | Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid. |
5 GO annotations of molecular function
| Name | Definition |
|---|---|
| ADP dimethylallyltransferase activity | Catalysis of the reaction: delta2-isopentenyl diphosphate + ADP = diphosphate + N6-(delta(2)-isopentenyl)adenosine 5'-diphosphate. |
| AMP dimethylallyltransferase activity | Catalysis of the reaction: AMP + dimethylallyl diphosphate = N(6)-(dimethylallyl)adenosine 5'-phosphate + diphosphate. |
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ATP dimethylallyltransferase activity | Catalysis of the reaction: delta(2)-isopentenyl diphosphate + ATP = diphosphate + N6-(delta(2)-isopentenyl)adenosine 5'-triphosphate. |
| tRNA dimethylallyltransferase activity | Catalysis of the reaction: dimethylallyl diphosphate + tRNA = diphosphate + tRNA containing 6-dimethylallyladenosine. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| cytokinin biosynthetic process | The chemical reactions and pathways resulting in the formation of cytokinins, a class of adenine-derived compounds that can function in plants as growth regulators. |
| tRNA modification | The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically. |
4 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P16384 | miaA | tRNA dimethylallyltransferase | Escherichia coli (strain K12) | PR |
| Q9H3H1 | TRIT1 | tRNA dimethylallyltransferase | Homo sapiens (Human) | PR |
| Q80UN9 | Trit1 | tRNA dimethylallyltransferase | Mus musculus (Mouse) | PR |
| Q9LJL4 | IPT8 | Adenylate isopentenyltransferase 8, chloroplastic | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MIMKISMAMC | KQPLPPSPTL | DFPPARFGPN | MLTLNPYGPK | DKVVVIMGAT | GTGKSRLSVD |
| 70 | 80 | 90 | 100 | 110 | 120 |
| IATRFRAEII | NSDKIQVHQG | LDIVTNKITS | EESCGVPHHL | LGVLPPEADL | TAANYCHMAN |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LSIESVLNRG | KLPIIVGGSN | SYVEALVDDK | ENKFRSRYDC | CFLWVDVALP | VLHGFVSERV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| DKMVESGMVE | EVREFFDFSN | SDYSRGIKKA | IGFPEFDRFF | RNEQFLNVED | REELLSKVLE |
| 250 | 260 | 270 | 280 | 290 | 300 |
| EIKRNTFELA | CRQREKIERL | RKVKKWSIQR | VDATPVFTKR | RSKMDANVAW | ERLVAGPSTD |
| 310 | 320 | 330 | |||
| TVSRFLLDIA | SRRPLVEAST | AVAAAMEREL | SRCLVA |