Q9FZ76
Gene name |
RPL6A (At1g18540, F25I16.12) |
Protein name |
60S ribosomal protein L6-1 |
Names |
|
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT1G18540 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9FZ76
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9FZ76-F1 | Predicted | AlphaFoldDB |
15 variants for Q9FZ76
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH13919961 | 7 | T>I | No | 1000Genomes | |
| ENSVATH04597039 | 50 | A>T | No | 1000Genomes | |
| tmp_1_6378383_C_T | 56 | A>T | No | 1000Genomes | |
| ENSVATH13919960 | 76 | N>Y | No | 1000Genomes | |
| ENSVATH01067399 | 89 | I>T | No | 1000Genomes | |
| ENSVATH00030782 | 114 | S>P | No | 1000Genomes | |
| ENSVATH01067394 | 146 | I>V | No | 1000Genomes | |
| tmp_1_6377812_T_A | 147 | D>V | No | 1000Genomes | |
| tmp_1_6377813_C_A | 147 | D>Y | No | 1000Genomes | |
| ENSVATH11468119 | 157 | D>N | No | 1000Genomes | |
| ENSVATH13919955 | 159 | K>M | No | 1000Genomes | |
| ENSVATH01067393 | 165 | A>V | No | 1000Genomes | |
| tmp_1_6377721_G_T | 177 | F>L | No | 1000Genomes | |
| tmp_1_6377588_G_A | 188 | P>S | No | 1000Genomes | |
| tmp_1_6377536_G_T | 205 | S>Y | No | 1000Genomes |
No associated diseases with Q9FZ76
6 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosolic large ribosomal subunit | The large subunit of a ribosome located in the cytosol. |
| cytosolic ribosome | A ribosome located in the cytosol. |
| endoplasmic reticulum | The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached). |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
| plasmodesma | A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| mRNA binding | Binding to messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns. |
| RNA binding | Binding to an RNA molecule or a portion thereof. |
| structural constituent of ribosome | The action of a molecule that contributes to the structural integrity of the ribosome. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| cytoplasmic translation | The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein. |
| ribosomal large subunit assembly | The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the large ribosomal subunit. |
3 homologous proteins in AiPD
| 10 | 20 | 30 | 40 | 50 | 60 |
| MPAAKRTPKV | NRNPDLIRGV | GKYSRSQMYH | KRGLWAIKAK | NGGVFPRHDA | QPKVDAPVEK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| PAKFYPAEDV | KKPLVNRRKP | KPTKLKASIT | PGTVLIILAG | RFKGKRVVFL | KQLSSGLLLV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| TGPFKINGVP | LRRVNQAYVI | GTSTKIDISG | VNTEKFDDKY | FGKVAEKKKK | KTEGEFFEAE |
| 190 | 200 | 210 | 220 | 230 | |
| KEEKKEIPQE | KKEDQKTVDA | ALIKSIEAVP | ELKVYLGARF | SLSQGMKPHE | LVF |