Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9C9C5

Entry ID Method Resolution Chain Position Source
AF-Q9C9C5-F1 Predicted AlphaFoldDB

20 variants for Q9C9C5

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_1_27848669_T_A 4 K>N No 1000Genomes
ENSVATH05142574 11 N>S No 1000Genomes
tmp_1_27848536_C_T 49 D>N No 1000Genomes
ENSVATH05142569 58 V>A No 1000Genomes
ENSVATH13805551 59 E>D No 1000Genomes
ENSVATH01533814 60 K>Q No 1000Genomes
ENSVATH13805550 68 E>K No 1000Genomes
tmp_1_27848474_A_T 69 D>E No 1000Genomes
ENSVATH05142568 80 A>S No 1000Genomes
tmp_1_27848434_T_A 83 T>S No 1000Genomes
tmp_1_27847963_A_C 97 I>S No 1000Genomes
ENSVATH13805546 108 V>I No 1000Genomes
ENSVATH05142538 114 A>P No 1000Genomes
ENSVATH05142537 121 T>S No 1000Genomes
ENSVATH14477966 138 Y>N No 1000Genomes
tmp_1_27847347_T_C 204 K>R No 1000Genomes
ENSVATH05142514 210 P>S No 1000Genomes
tmp_1_27847325_C_G 211 E>D No 1000Genomes
tmp_1_27847273_G_A 229 H>Y No 1000Genomes
ENSVATH01533805 230 E>V No 1000Genomes

No associated diseases with Q9C9C5

2 regional properties for Q9C9C5

Type Name Position InterPro Accession
domain Ribosomal protein L6, N-terminal 3 - 61 IPR005568
domain Ribosomal Protein L6, KOW domain 81 - 233 IPR041997

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
cytosolic large ribosomal subunit The large subunit of a ribosome located in the cytosol.
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
plasmodesma A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.

3 GO annotations of molecular function

Name Definition
mRNA binding Binding to messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
RNA binding Binding to an RNA molecule or a portion thereof.
structural constituent of ribosome The action of a molecule that contributes to the structural integrity of the ribosome.

2 GO annotations of biological process

Name Definition
cytoplasmic translation The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein.
ribosomal large subunit assembly The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the large ribosomal subunit.

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P47991 rpl-6 60S ribosomal protein L6 Caenorhabditis elegans PR
Q9C9C6 RPL6B 60S ribosomal protein L6-2 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FZ76 RPL6A 60S ribosomal protein L6-1 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MPAKQRTPKV NRNPDLIRGV GKYSRSQMYH KRGLWAIKAK NGGVFPRHDA KSKVDAPVEK
70 80 90 100 110 120
PPKFYPAEDV KKPLPNRRTA KPTKLRASIT PGTVLIILAG RFKGKRVVFL KQLASGLLLV
130 140 150 160 170 180
TGPFKINGVP LRRVNQAYVI GTSTKVDISG VTLDKFDDKY FGKVAEKKKK KTEGEFFEAE
190 200 210 220 230
KEEKKEIPQV KKDDQKAVDA ALIKAIEAVP ELKTYLGARF SLKQGMKPHE LVF