AiPD: Autoinhibited Protein Database

Gene name	RPL6B (At1g74060, F2P9.7)
Protein name	60S ribosomal protein L6-2
Names
Species	Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway	ath:AT1G74060
EC number
Protein Class

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

17-109 (Predicted disordered autoinhibitory region) PR

17-109 (Predicted disordered autoinhibitory region)

cis-regPred

No accessory elements

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q9C9C6-F1	Predicted				AlphaFoldDB

Variant ID(s)	Position	Change	Diseaes Association	Provenance
tmp_1_27851245_C_T	19	G>R	No	1000Genomes
tmp_1_27851172_C_T	43	G>D	No	1000Genomes
ENSVATH01533848	56	A>V	No	1000Genomes
ENSVATH01533847	61	P>A	No	1000Genomes
tmp_1_27851094_T_G	69	D>A	No	1000Genomes
ENSVATH01533844	80	A>P	No	1000Genomes
ENSVATH01533843	83	A>T	No	1000Genomes
tmp_1_27851048_C_A	84	K>N	No	1000Genomes
ENSVATH13805598	100	G>A	No	1000Genomes
ENSVATH14477987	109	F>L	No	1000Genomes
tmp_1_27850646_C_T	120	V>M	No	1000Genomes
tmp_1_27850643_T_C	121	T>A	No	1000Genomes
ENSVATH13805596	142	T>S	No	1000Genomes
ENSVATH01533828	145	K>N	No	1000Genomes
tmp_1_27850381_G_A	165	A>V	No	1000Genomes
ENSVATH05142634	190	G>V	No	1000Genomes
tmp_1_27850128_T_A	203	I>F	No	1000Genomes
ENSVATH13805587	209	V>I	No	1000Genomes
ENSVATH00142135	214	T>S	No	1000Genomes
tmp_1_27850063_T_A	224	Q>H	No	1000Genomes

Type	Name	Position	InterPro Accession
domain	Ribosomal protein L6, N-terminal	2 - 61	IPR005568
domain	Ribosomal Protein L6, KOW domain	81 - 233	IPR041997

		Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

Name	Definition
cytosolic large ribosomal subunit	The large subunit of a ribosome located in the cytosol.
cytosolic ribosome	A ribosome located in the cytosol.
mitochondrion	A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
nucleolus	A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.

Name	Definition
mRNA binding	Binding to messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
RNA binding	Binding to an RNA molecule or a portion thereof.
structural constituent of ribosome	The action of a molecule that contributes to the structural integrity of the ribosome.

Name	Definition
cytoplasmic translation	The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein.
ribosomal large subunit assembly	The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the large ribosomal subunit.

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
P47991	rpl-6	60S ribosomal protein L6	Caenorhabditis elegans	PR
Q9C9C5	RPL6C	60S ribosomal protein L6-3	Arabidopsis thaliana (Mouse-ear cress)	PR
Q9FZ76	RPL6A	60S ribosomal protein L6-1	Arabidopsis thaliana (Mouse-ear cress)	PR