P47991

PR
Gene name
rpl-6 (R151.3)
Protein name
60S ribosomal protein L6
Names
Species
Caenorhabditis elegans
KEGG Pathway
cel:CELE_R151.3
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

2-89 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P47991

Entry ID Method Resolution Chain Position Source
AF-P47991-F1 Predicted AlphaFoldDB

No variants for P47991

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P47991

No associated diseases with P47991

1 regional properties for P47991

Type Name Position InterPro Accession
conserved_site Ribosomal protein L1, conserved site 112 - 131 IPR023673

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm, cytosol
  • Cytoplasm
  • Rough endoplasmic reticulum
  • Detected on cytosolic polysomes (By similarity)
  • Detected in ribosomes that are associated with the rough endoplasmic reticulum (By similarity)
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytosolic large ribosomal subunit The large subunit of a ribosome located in the cytosol.
rough endoplasmic reticulum The rough (or granular) endoplasmic reticulum (ER) has ribosomes adhering to the outer surface; the ribosomes are the site of translation of the mRNA for those proteins which are either to be retained within the cisternae (ER-resident proteins), the proteins of the lysosomes, or the proteins destined for export from the cell. Glycoproteins undergo their initial glycosylation within the cisternae.

2 GO annotations of molecular function

Name Definition
RNA binding Binding to an RNA molecule or a portion thereof.
structural constituent of ribosome The action of a molecule that contributes to the structural integrity of the ribosome.

3 GO annotations of biological process

Name Definition
cytoplasmic translation The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein.
determination of adult lifespan The pathways that regulate the duration of the adult phase of the life-cycle of an animal.
ribosomal large subunit assembly The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the large ribosomal subunit.

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9C9C5 RPL6C 60S ribosomal protein L6-3 Arabidopsis thaliana (Mouse-ear cress) PR
Q9C9C6 RPL6B 60S ribosomal protein L6-2 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FZ76 RPL6A 60S ribosomal protein L6-1 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MVGKRNLPVI SRNFDLSPGV LRFSASRLRL KKGEKKPKFT KDTSAKLPKL QRNGTKFALG
70 80 90 100 110 120
HSKTVTLRKT LTPGTVLIVL AGRHKGKRVV FLKQLPQSGL LLVTGPHKIN GFPLRRIGQA
130 140 150 160 170 180
FVIATSLKVN VSGVKIPEHI NDEYFKRKST AQKTGKNIFA SGKTEYTVSE QRKKDIKTVD
190 200 210
APILAAIKKH PEHKFLFGYL GTRFSLGKNQ YPHKMQF