Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9FLG2

Entry ID Method Resolution Chain Position Source
AF-Q9FLG2-F1 Predicted AlphaFoldDB

14 variants for Q9FLG2

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_5_25809383_C_T 5 G>R No 1000Genomes
ENSVATH12928014 16 V>A No 1000Genomes
ENSVATH12928013 23 P>S No 1000Genomes
ENSVATH07478342 47 M>I No 1000Genomes
tmp_5_25808622_G_A 105 P>L No 1000Genomes
tmp_5_25808598_C_T 113 R>H No 1000Genomes
tmp_5_25808596_A_C 114 L>V No 1000Genomes
tmp_5_25808584_T_G 118 N>H No 1000Genomes
ENSVATH12927990 119 A>V No 1000Genomes
ENSVATH07478331 132 A>T No 1000Genomes
ENSVATH07478330 134 A>P No 1000Genomes
tmp_5_25807823_T_C 276 N>S No 1000Genomes
tmp_5_25807565_C_T 303 R>H No 1000Genomes
tmp_5_25807081_C_G 377 V>L No 1000Genomes

No associated diseases with Q9FLG2

No regional properties for Q9FLG2

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q9FLG2

Functions

Description
EC Number
Subcellular Localization
  • Membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

1 GO annotations of molecular function

Name Definition
magnesium ion transmembrane transporter activity Enables the transfer of magnesium (Mg) ions from one side of a membrane to the other.

2 GO annotations of biological process

Name Definition
magnesium ion transport The directed movement of magnesium (Mg) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
pollen development The process whose specific outcome is the progression of the pollen grain over time, from its formation to the mature structure. The process begins with the meiosis of the microsporocyte to form four haploid microspores. The nucleus of each microspore then divides by mitosis to form a two-celled organism, the pollen grain, that contains a tube cell as well as a smaller generative cell. The pollen grain is surrounded by an elaborate cell wall. In some species, the generative cell immediately divides again to give a pair of sperm cells. In most flowering plants, however this division takes place later, in the tube that develops when a pollen grain germinates.

6 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9HD23 MRS2 Magnesium transporter MRS2 homolog, mitochondrial Homo sapiens (Human) PR
Q5NCE8 Mrs2 Magnesium transporter MRS2 homolog, mitochondrial Mus musculus (Mouse) PR
Q9ET09 Mrs2 Magnesium transporter MRS2 homolog, mitochondrial Rattus norvegicus (Rat) PR
Q10S25 MRS2-H Putative magnesium transporter MRS2-H Oryza sativa subsp japonica (Rice) PR
Q9AUK4 MRS2-A Magnesium transporter MRS2-A, chloroplastic Oryza sativa subsp japonica (Rice) PR
Q304A0 MRS2-7 Magnesium transporter MRS2-7 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MAQNGYLVPA DPSAVVTVKK KTPQASWALI DATGQSEPLD VDKYEIMHRV QIHARDLRIL
70 80 90 100 110 120
DPNLSYPSTI LGRERAIVLN LEHIKAIITS EEVLLRDPSD ENVIPVVEEL RRRLPVGNAS
130 140 150 160 170 180
HNGGQGDGKE IAGAQNDGDT GDEDESPFEF RALEVALEAI CSFLAARTAE LETAAYPALD
190 200 210 220 230 240
ELTSKISSRN LDRVRKLKSA MTRLTARVQK VRDELEQLLD DDDDMADLYL SRKLSSASSP
250 260 270 280 290 300
ISSIGEPNWY TTSPTIGSKI SRASRASLAT VHGDENDVEE LEMLLEAYFM QIDSTLNRLT
310 320 330 340 350 360
TLREYIDDTE DYINIQLDNH RNQLIQLELV LSSGTVCLSM YSLVAGIFGM NIPYTWNDGH
370 380 390
GYMFKYVVGL TGTLCVVVFV IIMSYARYKG LVGS