Q304A0

PR
Gene name
MRS2-7 (MGT7, At5g09690, F17I14.120)
Protein name
Magnesium transporter MRS2-7
Names
Magnesium Transporter 7, AtMGT7
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT5G09690
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-48 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q304A0

Entry ID Method Resolution Chain Position Source
AF-Q304A0-F1 Predicted AlphaFoldDB

19 variants for Q304A0

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_5_3003159_T_C 4 D>G No 1000Genomes
ENSVATH13970433 18 A>G No 1000Genomes
tmp_5_3003105_G_A 22 T>I No 1000Genomes
tmp_5_3003095_T_G 25 L>F No 1000Genomes
ENSVATH06944750 26 S>L No 1000Genomes
tmp_5_3002980_G_A 64 P>S No 1000Genomes
ENSVATH06944749 70 S>C No 1000Genomes
tmp_5_3002944_C_G 76 E>Q No 1000Genomes
ENSVATH00613479 122 A>E No 1000Genomes
ENSVATH00613478 125 V>A No 1000Genomes
ENSVATH00613477 131 L>V No 1000Genomes
ENSVATH00613472 165 F>S No 1000Genomes
tmp_5_3001816_G_T 245 P>Q No 1000Genomes
ENSVATH03040678 257 V>M No 1000Genomes
ENSVATH00613468 260 V>A No 1000Genomes
ENSVATH13970430 296 E>* No 1000Genomes
tmp_5_3001273_C_G 322 M>I No 1000Genomes
tmp_5_3001049_T_A 368 I>L No 1000Genomes
ENSVATH03040668 380 F>V No 1000Genomes

No associated diseases with Q304A0

No regional properties for Q304A0

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q304A0

Functions

Description
EC Number
Subcellular Localization
  • Endoplasmic reticulum membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
endoplasmic reticulum membrane The lipid bilayer surrounding the endoplasmic reticulum.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

1 GO annotations of molecular function

Name Definition
magnesium ion transmembrane transporter activity Enables the transfer of magnesium (Mg) ions from one side of a membrane to the other.

1 GO annotations of biological process

Name Definition
magnesium ion transport The directed movement of magnesium (Mg) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

6 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9HD23 MRS2 Magnesium transporter MRS2 homolog, mitochondrial Homo sapiens (Human) PR
Q5NCE8 Mrs2 Magnesium transporter MRS2 homolog, mitochondrial Mus musculus (Mouse) PR
Q9ET09 Mrs2 Magnesium transporter MRS2 homolog, mitochondrial Rattus norvegicus (Rat) PR
Q10S25 MRS2-H Putative magnesium transporter MRS2-H Oryza sativa subsp japonica (Rice) PR
Q9AUK4 MRS2-A Magnesium transporter MRS2-A, chloroplastic Oryza sativa subsp japonica (Rice) PR
Q9FLG2 MRS2-2 Magnesium transporter MRS2-2 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MSPDGELVPV DSSAVVTAKR KTSQLSRSWI SIDATGQKTV LDVDKHVIMH RVQIHARDLR
70 80 90 100 110 120
ILDPNLFYPS AILGRERAIV LNLEHIKAII TAEEVLIRDS SDENVIPVLE EFQRRLPVGN
130 140 150 160 170 180
EAHGVHGDGD LGEEDESPFE FRALEVALEA ICSFLAARTT ELEKFAYPAL DELTLKISSR
190 200 210 220 230 240
NLERVRKLKS AMTRLTARVQ KVRDELEQLL DDDGDMADLY LTRKLVGASS SVSVSDEPIW
250 260 270 280 290 300
YPTSPTIGSM ISRASRVSLV TVRGDDETDV EELEMLLEAY FMQIDSTLNK LTELREYIDD
310 320 330 340 350 360
TEDYINIQLD NHRNQLIQLE LMLSAGTVCV SVYSMIAGIF GMNIPNTWNH DHGYIFKWVV
370 380
SLTGTFCIVL FVIILSYARF RGLIGS