Q9ET09
Gene name |
Mrs2 (Mrs2l, Rpt) |
Protein name |
Magnesium transporter MRS2 homolog, mitochondrial |
Names |
MRS2-like protein |
Species |
Rattus norvegicus (Rat) |
KEGG Pathway |
rno:79032 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9ET09
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9ET09-F1 | Predicted | AlphaFoldDB |
1 variants for Q9ET09
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs3323144955 | 89 | T>I | No | EVA |
No associated diseases with Q9ET09
No regional properties for Q9ET09
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q9ET09 | |||
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| mitochondrial inner membrane | The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae. |
| mitochondrion | A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| magnesium ion transmembrane transporter activity | Enables the transfer of magnesium (Mg) ions from one side of a membrane to the other. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| lactate metabolic process | The chemical reactions and pathways involving lactate, the anion of lactic acid. |
| magnesium ion transport | The directed movement of magnesium (Mg) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| mitochondrial magnesium ion transmembrane transport | The process in which a magnesium ion (Mg2+) is transported across a mitochondrial membrane, into or out of the mitochondrion. |
6 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q9HD23 | MRS2 | Magnesium transporter MRS2 homolog, mitochondrial | Homo sapiens (Human) | PR |
| Q5NCE8 | Mrs2 | Magnesium transporter MRS2 homolog, mitochondrial | Mus musculus (Mouse) | PR |
| Q10S25 | MRS2-H | Putative magnesium transporter MRS2-H | Oryza sativa subsp japonica (Rice) | PR |
| Q9AUK4 | MRS2-A | Magnesium transporter MRS2-A, chloroplastic | Oryza sativa subsp japonica (Rice) | PR |
| Q304A0 | MRS2-7 | Magnesium transporter MRS2-7 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9FLG2 | MRS2-2 | Magnesium transporter MRS2-2 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MECLRYLPRL | LPRAAQSRSA | LCMAAVRLSL | AACCGRATPL | TSGSQKAPST | PRTAGDVYRF |
| 70 | 80 | 90 | 100 | 110 | 120 |
| RTSDASQATL | ASVAQVFAVT | KFDKEGNVTS | FERKKTELYH | ELALQARDLR | FQHVMSITTR |
| 130 | 140 | 150 | 160 | 170 | 180 |
| NNRIIMRMEY | LKAVITPEYL | LILDYRNLNL | EHWLFRELPS | QLAGEGQLVT | YPLPFEFRAI |
| 190 | 200 | 210 | 220 | 230 | 240 |
| EALLQYWINT | LQGKLSILQP | LILETLDALV | DPKHSSVDRS | KLHVLLQNGK | SLSELETDIK |
| 250 | 260 | 270 | 280 | 290 | 300 |
| IFKESILELL | DEEEMLEELC | LTKWSDPHVF | EQSSTGIDHA | EEMELLLENY | YRLADDLSNE |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ARELRVLIDD | SQSIIFINLD | SHRNVMMRLN | LQLTMGTFSL | SLFGLMGVAF | GMNLESSLEE |
| 370 | 380 | 390 | 400 | 410 | 420 |
| DHRVFWLITG | IMFMGSGLIW | RRLLSFLGRQ | LEAPLPPVMA | SLPKKTLLAD | RRMDVKNSLR |
| 430 | |||||
| PEGLGAGRTI | LASR |