Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9FLF0

Entry ID Method Resolution Chain Position Source
AF-Q9FLF0-F1 Predicted AlphaFoldDB

10 variants for Q9FLF0

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_5_15950070_C_A 6 F>L No 1000Genomes
tmp_5_15950461_C_T 28 A>V No 1000Genomes
ENSVATH00689437 85 Y>H No 1000Genomes
tmp_5_15950650_C_T 91 T>I No 1000Genomes
ENSVATH03295840 93 N>T No 1000Genomes
ENSVATH07272587 129 V>I No 1000Genomes
ENSVATH14551931 149 M>I No 1000Genomes
tmp_5_15951054_C_G 159 D>E No 1000Genomes
tmp_5_15951122_G_T 182 G>V No 1000Genomes
tmp_5_15951154_G_A 193 E>K No 1000Genomes

No associated diseases with Q9FLF0

3 regional properties for Q9FLF0

Type Name Position InterPro Accession
domain Ribosomal protein S4/S9, N-terminal 8 - 108 IPR001912
domain RNA-binding S4 domain 109 - 173 IPR002942
conserved_site Ribosomal protein S4, conserved site 107 - 131 IPR018079

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
cytosolic small ribosomal subunit The small subunit of a ribosome located in the cytosol.
plasmodesma A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.
plastid Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid.
small ribosomal subunit The smaller of the two subunits of a ribosome.

3 GO annotations of molecular function

Name Definition
mRNA binding Binding to messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
rRNA binding Binding to a ribosomal RNA.
structural constituent of ribosome The action of a molecule that contributes to the structural integrity of the ribosome.

2 GO annotations of biological process

Name Definition
positive regulation of translational fidelity Any process that increases the ability of the translational apparatus to interpret the genetic code.
translation The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.

7 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
A6QLG5 RPS9 40S ribosomal protein S9 Bos taurus (Bovine) PR
P0A7V8 rpsD 30S ribosomal protein S4 Escherichia coli (strain K12) PR
P55935 RpS9 40S ribosomal protein S9 Drosophila melanogaster (Fruit fly) PR
P46781 RPS9 40S ribosomal protein S9 Homo sapiens (Human) PR
Q6ZWN5 Rps9 40S ribosomal protein S9 Mus musculus (Mouse) PR
P29314 Rps9 40S ribosomal protein S9 Rattus norvegicus (Rat) PR
Q20228 rps-9 40S ribosomal protein S9 Caenorhabditis elegans PR
10 20 30 40 50 60
MVNVRFYRNY GKTFKKPRRP YEKERLDAEL KLVGEYGLRC KRELWRVQYT LSRIRNAARE
70 80 90 100 110 120
LLTLDEKNPR RIFEGEALLR RMNRYGLLDE TQNKLDYVLA LTVENFLERR LQTIVFKSGM
130 140 150 160 170 180
AKSIHHARVL IRQRHIRVGR QLVNIPSFMV RVESQKHVDF SLTSPFGGGR PGRVKRRNER
190
AGAKKASGGD GDEDDEE