Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

5 structures for P55935

Entry ID Method Resolution Chain Position Source
4V6W EM 600 A AJ 1-195 PDB
6XU6 EM 350 A AJ 4-184 PDB
6XU7 EM 490 A AJ 4-184 PDB
6XU8 EM 300 A AJ 4-184 PDB
AF-P55935-F1 Predicted AlphaFoldDB

No variants for P55935

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P55935

No associated diseases with P55935

3 regional properties for P55935

Type Name Position InterPro Accession
domain Ribosomal protein S4/S9, N-terminal 4 - 108 IPR001912
domain RNA-binding S4 domain 109 - 180 IPR002942
conserved_site Ribosomal protein S4, conserved site 107 - 131 IPR018079

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Nucleus, nucleolus
  • Localized in cytoplasmic mRNP granules containing untranslated mRNAs
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

6 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
cytosolic ribosome A ribosome located in the cytosol.
cytosolic small ribosomal subunit The small subunit of a ribosome located in the cytosol.
nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
small ribosomal subunit The smaller of the two subunits of a ribosome.

2 GO annotations of molecular function

Name Definition
rRNA binding Binding to a ribosomal RNA.
structural constituent of ribosome The action of a molecule that contributes to the structural integrity of the ribosome.

2 GO annotations of biological process

Name Definition
cytoplasmic translation The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein.
positive regulation of translational fidelity Any process that increases the ability of the translational apparatus to interpret the genetic code.

7 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
A6QLG5 RPS9 40S ribosomal protein S9 Bos taurus (Bovine) PR
P0A7V8 rpsD 30S ribosomal protein S4 Escherichia coli (strain K12) PR
P46781 RPS9 40S ribosomal protein S9 Homo sapiens (Human) PR
Q6ZWN5 Rps9 40S ribosomal protein S9 Mus musculus (Mouse) PR
P29314 Rps9 40S ribosomal protein S9 Rattus norvegicus (Rat) PR
Q20228 rps-9 40S ribosomal protein S9 Caenorhabditis elegans PR
Q9FLF0 RPS9C 40S ribosomal protein S9-2 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MVNGRIPSVF SKTYVTPRRP YEKARLDQEL KIIGEYGLRN KREVWRVKYA LAKIRKAARE
70 80 90 100 110 120
LLTLDEKDEK RLFQGNALLR RLVRIGVLDE SRMKLDYVLG LKIEDFLERR LQTQVFKLGL
130 140 150 160 170 180
AKSIHHARVL IRQRHIRVRK QVVNIPSFVV RLDSQKHIDF SLKSPFGGGR PGRVKRKNLK
190
KNQGGGGGAA EEEED