Q9FGS8
PR
Gene name |
At5g50170 (K6A12_3) |
Protein name |
C2 and GRAM domain-containing protein At5g50170 |
Names |
|
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT5G50170 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9FGS8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9FGS8-F1 | Predicted | AlphaFoldDB |
76 variants for Q9FGS8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_5_20421156_C_T | 3 | L>F | No | 1000Genomes | |
| tmp_5_20421228_C_G | 27 | H>D | No | 1000Genomes | |
| tmp_5_20421229_A_T | 27 | H>L | No | 1000Genomes | |
| ENSVATH07387849 | 27 | H>Q | No | 1000Genomes | |
| tmp_5_20421255_G_T,A | 36 | D>N | No | 1000Genomes | |
| tmp_5_20421255_G_T,A | 36 | D>Y | No | 1000Genomes | |
| tmp_5_20421345_C_T | 66 | H>Y | No | 1000Genomes | |
| tmp_5_20421360_C_T | 71 | H>Y | No | 1000Genomes | |
| tmp_5_20421400_G_T | 84 | R>L | No | 1000Genomes | |
| ENSVATH07387850 | 88 | T>S | No | 1000Genomes | |
| tmp_5_20421471_C_T | 108 | P>S | No | 1000Genomes | |
| ENSVATH12679683 | 136 | G>C | No | 1000Genomes | |
| ENSVATH12679684 | 157 | G>R | No | 1000Genomes | |
| tmp_5_20422161_C_G | 159 | P>R | No | 1000Genomes | |
| ENSVATH07387867 | 160 | K>Q | No | 1000Genomes | |
| ENSVATH03403848 | 164 | S>F | No | 1000Genomes | |
| tmp_5_20422197_G_A | 171 | R>H | No | 1000Genomes | |
| ENSVATH03403849 | 205 | S>Y | No | 1000Genomes | |
| tmp_5_20422311_A_G | 209 | Q>R | No | 1000Genomes | |
| tmp_5_20422388_C_G | 235 | L>V | No | 1000Genomes | |
| tmp_5_20422402_G_C | 239 | Q>H | No | 1000Genomes | |
| ENSVATH07387868 | 244 | E>K | No | 1000Genomes | |
| tmp_5_20422527_G_A | 281 | R>K | No | 1000Genomes | |
| tmp_5_20422533_A_G | 283 | E>G | No | 1000Genomes | |
| ENSVATH12679706 | 284 | L>V | No | 1000Genomes | |
| ENSVATH07387870 | 287 | L>H | No | 1000Genomes | |
| ENSVATH12679707 | 324 | A>V | No | 1000Genomes | |
| ENSVATH07387872 | 334 | R>W | No | 1000Genomes | |
| tmp_5_20422694_A_G | 337 | S>G | No | 1000Genomes | |
| tmp_5_20422695_G_T | 337 | S>I | No | 1000Genomes | |
| ENSVATH00724396 | 343 | V>I | No | 1000Genomes | |
| ENSVATH03403850 | 364 | Y>F | No | 1000Genomes | |
| ENSVATH14621237 | 376 | G>E | No | 1000Genomes | |
| ENSVATH07387873 | 383 | I>V | No | 1000Genomes | |
| ENSVATH14621238 | 413 | Q>K | No | 1000Genomes | |
| tmp_5_20422929_C_G | 415 | S>C | No | 1000Genomes | |
| ENSVATH14621239 | 423 | K>E | No | 1000Genomes | |
| ENSVATH12679708 | 430 | V>L | No | 1000Genomes | |
| ENSVATH03403852 | 465 | L>V | No | 1000Genomes | |
| tmp_5_20423085_C_G | 467 | S>C | No | 1000Genomes | |
| tmp_5_20423099_G_T | 472 | V>F | No | 1000Genomes | |
| tmp_5_20423107_G_A | 474 | M>I | No | 1000Genomes | |
| ENSVATH14621240 | 487 | F>L | No | 1000Genomes | |
| ENSVATH07387874 | 495 | S>T | No | 1000Genomes | |
| ENSVATH00724399 | 504 | I>L | No | 1000Genomes | |
| ENSVATH03403853 | 505 | L>I | No | 1000Genomes | |
| ENSVATH07387875 | 506 | V>A | No | 1000Genomes | |
| ENSVATH00724400 | 514 | I>M | No | 1000Genomes | |
| tmp_5_20423235_T_G | 517 | V>G | No | 1000Genomes | |
| tmp_5_20423349_G_A | 527 | G>E | No | 1000Genomes | |
| tmp_5_20423375_G_T | 536 | G>C | No | 1000Genomes | |
| tmp_5_20423493_G_T | 575 | S>I | No | 1000Genomes | |
| tmp_5_20423516_G_C | 583 | D>H | No | 1000Genomes | |
| tmp_5_20423656_C_G | 598 | P>A | No | 1000Genomes | |
| ENSVATH03403856 | 610 | D>G | No | 1000Genomes | |
| tmp_5_20423699_C_T | 612 | P>L | No | 1000Genomes | |
| tmp_5_20423814_G_C | 650 | Q>H | No | 1000Genomes | |
| tmp_5_20423850_G_T | 662 | K>N | No | 1000Genomes | |
| tmp_5_20424045_C_G | 688 | P>A | No | 1000Genomes | |
| tmp_5_20424359_A_T | 742 | T>S | No | 1000Genomes | |
| ENSVATH07387883 | 787 | S>T | No | 1000Genomes | |
| tmp_5_20424527_T_C | 798 | F>L | No | 1000Genomes | |
| ENSVATH00724405 | 806 | A>G | No | 1000Genomes | |
| tmp_5_20424662_C_G | 813 | A>G | No | 1000Genomes | |
| tmp_5_20424718_G_A | 832 | D>N | No | 1000Genomes | |
| tmp_5_20424822_C_G | 866 | C>W | No | 1000Genomes | |
| tmp_5_20425051_C_T | 900 | S>F | No | 1000Genomes | |
| ENSVATH00724406 | 903 | P>Q | No | 1000Genomes | |
| tmp_5_20425180_A_C | 943 | N>T | No | 1000Genomes | |
| tmp_5_20425321_A_G | 961 | I>V | No | 1000Genomes | |
| ENSVATH00724407 | 972 | C>G | No | 1000Genomes | |
| tmp_5_20425357_A_G | 973 | K>E | No | 1000Genomes | |
| tmp_5_20425361_C_T | 974 | T>I | No | 1000Genomes | |
| tmp_5_20425417_C_G | 993 | Q>E | No | 1000Genomes | |
| tmp_5_20425431_A_T | 997 | K>N | No | 1000Genomes | |
| ENSVATH12679719 | 1012 | D>E | No | 1000Genomes |
No associated diseases with Q9FGS8
5 regional properties for Q9FGS8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | C2 domain | 1 - 103 | IPR000008-1 |
| domain | C2 domain | 516 - 639 | IPR000008-2 |
| domain | GRAM domain | 692 - 775 | IPR004182 |
| domain | VASt domain | 253 - 426 | IPR031968-1 |
| domain | VASt domain | 855 - 1018 | IPR031968-2 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
5 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q8IYS0 | GRAMD1C | Protein Aster-C | Homo sapiens (Human) | PR |
| Q3KR37 | GRAMD1B | Protein Aster-B | Homo sapiens (Human) | PR |
| Q96CP6 | GRAMD1A | Protein Aster-A | Homo sapiens (Human) | PR |
| Q80TI0 | Gramd1b | Protein Aster-B | Mus musculus (Mouse) | PR |
| Q9ZVT9 | At1g03370 | C2 and GRAM domain-containing protein At1g03370 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MRLYVYILQA | KDLPAKETFA | KLHVGRHKSK | TRVARDTSSP | IWNEEFVFRI | SDVDEGDDVV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VSILHHEQQD | HQSIVSTGLI | GKVRIPLTSV | AAEENQTLLP | TWFVIEKPSD | GKFVNIECGK |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ILLSLSLQGK | WESTSGEKVL | NDKQDIINLE | GVKELEGSPK | DLISSRDGKR | RKHHDGKHIM |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KNIVNHIDKL | FHKKEEISKR | LHDESSVGQS | VNSNYEDATD | QCSSSATCTG | FEEGLDLMQS |
| 250 | 260 | 270 | 280 | 290 | 300 |
| SDSEREEMPE | NLTGGVLVDQ | KYLVSPCELN | KFLFTPSSQF | RKELAELQGL | SDVQEGPWTM |
| 310 | 320 | 330 | 340 | 350 | 360 |
| MQEDTPRLTR | VVTYMRAATK | MVKAVKATEN | QVYRKASGKQ | FAVFVSVSTP | DVPYGNTFKI |
| 370 | 380 | 390 | 400 | 410 | 420 |
| ELLYKILPET | EPTAGGEASR | LIISWGIQFS | QSTIMKGMIE | GGARQGLKES | FEQFSNLLAK |
| 430 | 440 | 450 | 460 | 470 | 480 |
| TYKTLDPAVV | LDKEQVIATV | QSEPKTDLKS | AFLYFWSSSV | ICAVLLSVYV | VVHMLHCEPS |
| 490 | 500 | 510 | 520 | 530 | 540 |
| KIQGFEFYGL | DLPDSFGELF | SSGILVLLLE | RVYIMTVHFV | QARLHRGRDQ | GVKANGKGWI |
| 550 | 560 | 570 | 580 | 590 | 600 |
| LTIALIKGTN | LASVEATELF | DPYVVFTCNG | KTRTSSVKLQ | AQDPQWNEVI | EFDAMEEPPS |
| 610 | 620 | 630 | 640 | 650 | 660 |
| VLDVEVFDFD | GPFDQGASLG | HAEINFLKHT | ADELADLSVA | LVGNHAQASQ | SKLQLRIFLE |
| 670 | 680 | 690 | 700 | 710 | 720 |
| NKNGVETMKD | YLSKVEKEVG | KKLNIRSPQK | NSAFQKLFGL | PHEEFLLKEY | TCYLKRKLPV |
| 730 | 740 | 750 | 760 | 770 | 780 |
| QGKLFLSARI | VAFYSNVFGH | KTKFYFLWED | IDDIQVLPPT | FASLGSPLLL | IILKKNRGLD |
| 790 | 800 | 810 | 820 | 830 | 840 |
| AKHGAKSQDD | EGRLSFYFQS | FVSFDATSRT | IMALWKTRTL | SVDHRAQIVE | EDQDVADPFL |
| 850 | 860 | 870 | 880 | 890 | 900 |
| LPEAVTVVSD | ADALMMSKVY | TCDLPCDVEL | VMKIFGGGEL | ERKIMEKSGC | LSYASTTWES |
| 910 | 920 | 930 | 940 | 950 | 960 |
| KKPGVYERRL | SYKYNHYVSV | FGGGVTCAQQ | KSPAPNDEGW | ILNEIVALHD | VPFGDHFRVH |
| 970 | 980 | 990 | 1000 | 1010 | 1020 |
| IRYEVKKAGV | DCKTSKCEVY | LKIRWLKTIK | FEQRISKSIM | EKFRNRFKVI | FDLFQKESVA |
| NSSLTLL |