Q9D0R9

PR
Gene name
Wdr89
Protein name
WD repeat-containing protein 89
Names
Species
Mus musculus (Mouse)
KEGG Pathway
mmu:72338
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

328-386 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9D0R9

Entry ID Method Resolution Chain Position Source
AF-Q9D0R9-F1 Predicted AlphaFoldDB

32 variants for Q9D0R9

Variant ID(s) Position Change Description Diseaes Association Provenance
rs3389254614 20 P>L No EVA
rs3410930442 37 A>V No EVA
rs214231515 38 D>E No EVA
rs3389252241 49 N>Y No EVA
rs227515425 67 G>S No EVA
rs3389254677 80 N>H No EVA
rs3389247795 81 S>F No EVA
rs254717596 84 S>N No EVA
rs238241407 101 G>V No EVA
rs3389247822 105 K>R No EVA
rs3402112648 116 C>* No EVA
rs3389246525 116 C>Y No EVA
rs3389246488 145 F>Y No EVA
rs3389177304 152 S>F No EVA
rs3389213027 188 G>R No EVA
rs219694529 203 K>N No EVA
rs3389257533 215 V>A No EVA
rs231183547 220 C>S No EVA
rs3389203595 223 W>* No EVA
rs3389257558 237 D>N No EVA
rs251090727 241 C>G No EVA
rs3403457199 249 D>Y No EVA
rs3402740070 250 T>P No EVA
rs3389229762 263 R>* No EVA
rs3389257509 272 H>Q No EVA
rs234701057 326 F>Y No EVA
rs3389203641 327 C>* No EVA
rs3389243900 331 S>C No EVA
rs3389257586 332 E>D No EVA
rs3389242606 339 G>C No EVA
rs237145266 355 T>A No EVA
rs3403765564 361 S>I No EVA

No associated diseases with Q9D0R9

5 regional properties for Q9D0R9

Type Name Position InterPro Accession
repeat WD40 repeat 20 - 56 IPR001680-1
repeat WD40 repeat 59 - 147 IPR001680-2
repeat WD40 repeat 157 - 207 IPR001680-3
repeat WD40 repeat 205 - 244 IPR001680-4
repeat WD40 repeat 308 - 348 IPR001680-5

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
corpus callosum development The process whose specific outcome is the progression of the corpus callosum over time, from its formation to the mature structure. The corpus callosum is a thick bundle of nerve fibers comprising a commissural plate connecting the two cerebral hemispheres. It consists of contralateral axon projections that provide communication between the right and left cerebral hemispheres.

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P53962 YNL035C Uncharacterized WD repeat-containing protein YNL035C Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PR
Q3ZBK1 WDR89 WD repeat-containing protein 89 Bos taurus (Bovine) PR
Q96FK6 WDR89 WD repeat-containing protein 89 Homo sapiens (Human) PR
10 20 30 40 50 60
MEKIEDQFAS LHIVRRSSEP KEPTYLLGID TSKTVQADKG GLVAVLCSNG SIRIYDKETL
70 80 90 100 110 120
HLLREFGGSP GLLSGVSFAN SCDSVYSAST DGTVKCWDAR GASEKPVQLF KGYPSCSFIS
130 140 150 160 170 180
FDVNCKDHVI CAGAEKVDED ALLVFWDARF TSQDLSTRDP LGAYSETHSD DITQVRFHPS
190 200 210 220 230 240
NPNLVVSGST DGLVNVFDLS ADKEEDALVA TCNSVSSVSC IGWCGKDYKQ IYCMTHDEGF
250 260 270 280 290 300
CWWDLNHLDT DEPITCLNIQ DVREITDVKD GHLDYLIGGL YHEKMDRLFV IGGTNTGKIH
310 320 330 340 350 360
LLSCTSAGLT HVTSLHGGHA ATVRSFCWNV SEDSLLTGGE DAQLLLWKPG AMEKTFTKKD
370 380
SLKIASSVQQ RVRVHSSDSY KKRKQQ