P53962

PR
Gene name
YNL035C (N2730)
Protein name
Uncharacterized WD repeat-containing protein YNL035C
Names
Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
KEGG Pathway
sce:YNL035C
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

317-389 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P53962

Entry ID Method Resolution Chain Position Source
AF-P53962-F1 Predicted AlphaFoldDB

11 variants for P53962

Variant ID(s) Position Change Description Diseaes Association Provenance
s14-569551 48 S>P No SGRP
s14-569382 104 P>L No SGRP
s14-568997 232 Q>H No SGRP
s14-568988 235 D>E No SGRP
s14-568967 242 I>M No SGRP
s14-568968 242 I>T No SGRP
s14-568903 264 N>D No SGRP
s14-568888 269 C>R No SGRP
s14-568779 305 S>N No SGRP
s14-568590 368 R>K No SGRP
s14-568548 382 M>T No SGRP

No associated diseases with P53962

4 regional properties for P53962

Type Name Position InterPro Accession
repeat WD40 repeat 3 - 42 IPR001680-1
repeat WD40 repeat 45 - 87 IPR001680-2
repeat WD40 repeat 137 - 186 IPR001680-3
repeat WD40 repeat 280 - 321 IPR001680-4

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q3ZBK1 WDR89 WD repeat-containing protein 89 Bos taurus (Bovine) PR
Q96FK6 WDR89 WD repeat-containing protein 89 Homo sapiens (Human) PR
Q9D0R9 Wdr89 WD repeat-containing protein 89 Mus musculus (Mouse) PR
10 20 30 40 50 60
MASYSLVESN SFGSENWCLK LQPSYKHGLL TGLSNGEIRL LDWSTGKSVQ KIKASETAIN
70 80 90 100 110 120
DMKVIGSDFS AGHLVSSASI DAVKVFDIRT NDRIAQIQNE ANSPFISLDS RHGLLACGTE
130 140 150 160 170 180
LQGIDAAVYI YDIRKWDTPL RSLIDSHHDD VTCIKFHPSD VNILLSGSTD GYTNIYDLKQ
190 200 210 220 230 240
DEEEDALHQV INYASIHSCG WLSPKRIFTL SHMETFAIHE LNDKSDELKE PQPLDFGDVR
250 260 270 280 290 300
EIWNCDYVVD IYPGLIATGK TQENCGELCL LPFKDEKVDT ENGIVIPHAH GDEVVRDIFI
310 320 330 340 350 360
PAQHSNMLYS CGEDGCVKIW ENKQGPLDIP ENFWDYSKKM NVLGDDDREG SINLDEPLII
370 380
QKESVSTRPR KEKHKKAKKH SMKSRFKPY