Q3ZBK1

PR
Gene name
WDR89
Protein name
WD repeat-containing protein 89
Names
Species
Bos taurus (Bovine)
KEGG Pathway
bta:539045
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-62 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q3ZBK1

Entry ID Method Resolution Chain Position Source
AF-Q3ZBK1-F1 Predicted AlphaFoldDB

36 variants for Q3ZBK1

Variant ID(s) Position Change Description Diseaes Association Provenance
rs380892152 16 R>C No EVA
rs482387007 159 E>D No EVA
rs378643727 176 R>C No EVA
rs798180889 200 S>G No EVA
rs442301836 219 S>C No EVA
rs452864625 232 Y>C No EVA
rs475346781 232 Y>N No EVA
rs455366358 242 W>R No EVA
rs440828307 329 N>K No EVA
rs470688115 330 M>T No EVA
rs452086046 331 Q>R No EVA
rs469768544 333 D>V No EVA
rs436877222 333 D>Y No EVA
rs454578408 334 S>F No EVA
rs436247027 335 L>V No EVA
rs1116663711 338 G>A No EVA
rs446815347 339 G>E No EVA
rs479889940 341 D>N No EVA
rs479889940 341 D>Y No EVA
rs718533747 342 A>E No EVA
rs464586684 342 A>S No EVA
rs464586684 342 A>T No EVA
rs482323791 343 Q>H No EVA
rs463950782 344 L>F No EVA
rs442283903 345 L>F No EVA
rs481700816 346 L>F No EVA
rs441528952 347 W>* No EVA
rs460027564 347 W>L No EVA
rs470539630 348 K>N No EVA
rs458561269 351 A>G No EVA
rs443239596 364 I>T No EVA
rs476159526 367 S>A No EVA
rs454566010 369 H>P No EVA
rs472505384 370 Q>E No EVA
rs453913409 371 R>L No EVA
rs432271273 373 R>C No EVA

No associated diseases with Q3ZBK1

3 regional properties for Q3ZBK1

Type Name Position InterPro Accession
domain Helicase, superfamily 3, DNA virus 607 - 775 IPR014015
domain Bacteriophage/plasmid primase, P4, C-terminal 419 - 600 IPR014818
domain Primase, C-terminal 2 304 - 382 IPR014819

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P53962 YNL035C Uncharacterized WD repeat-containing protein YNL035C Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PR
Q96FK6 WDR89 WD repeat-containing protein 89 Homo sapiens (Human) PR
Q9D0R9 Wdr89 WD repeat-containing protein 89 Mus musculus (Mouse) PR
10 20 30 40 50 60
MEKIEEQFAN LNIVKRSSET KEPTYLLGID TSKTVQTEKG SLVAVLCSNG SIRIHDKERL
70 80 90 100 110 120
NVIREFRGYP GLNGVKFANS HDSVYSSCTD GTVKCWDARL ASGKPVQLFK GYPSNIFISF
130 140 150 160 170 180
DISSNDHVIC AGTEKVDDDA LLVFWDARIN SQDLSTTKEP LGAYSETHSD DITQVRFHPS
190 200 210 220 230 240
NPNMVVSGST DGLVNVFDIS ADNEDDALVT TCNSVSSVSF IGWSGKDYKQ IYCMTHDEGF
250 260 270 280 290 300
CWWDLNHLDT DEPITCLNVP DVREVINVKE GILDYLIGGL YHEKTDKLFV VGGTNTGIIR
310 320 330 340 350 360
IMNCMTSGLV HVTSLQGGHA ATVRSFCWNM QDDSLLTGGE DAQLLLWKPG AVEKTFTKKD
370 380
SMKIASSVHQ RVRVHSNDSY KRRKKQ