Q9CQS3

PR
Gene name
Fibin
Protein name
Fin bud initiation factor homolog
Names
Species
Mus musculus (Mouse)
KEGG Pathway
mmu:67606
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

105-177 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9CQS3

Entry ID Method Resolution Chain Position Source
AF-Q9CQS3-F1 Predicted AlphaFoldDB

3 variants for Q9CQS3

Variant ID(s) Position Change Description Diseaes Association Provenance
rs248402247 70 G>D No EVA
rs3388573004 85 T>R No EVA
rs3388572066 102 S>C No EVA

No associated diseases with Q9CQS3

No regional properties for Q9CQS3

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q9CQS3

Functions

Description
EC Number
Subcellular Localization
  • Secreted
  • Golgi apparatus
  • Endoplasmic reticulum
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
endoplasmic reticulum The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
extracellular region The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
Golgi apparatus A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways.

1 GO annotations of molecular function

Name Definition
protein homodimerization activity Binding to an identical protein to form a homodimer.

3 GO annotations of biological process

Name Definition
protein kinase C signaling A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound.
response to dexamethasone Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dexamethasone stimulus.
response to manganese ion Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a manganese ion stimulus.

4 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q5E9H1 FIBIN Fin bud initiation factor homolog Bos taurus (Bovine) PR
A4UZ23 FIBIN Fin bud initiation factor homolog Equus caballus (Horse) PR
Q8TAL6 FIBIN Fin bud initiation factor homolog Homo sapiens (Human) PR
A1IGX5 fibin Fin bud initiation factor Danio rerio (Zebrafish) (Brachydanio rerio) PR
10 20 30 40 50 60
MVFPKLIWMG FFCHLCRGYF DGPLYPEMSN GTLHHYFVPD GDYEENDDPE KCQLLFRVSD
70 80 90 100 110 120
RRRCSQGEGG QASSLLSLTL REEFTVLGRQ VEDAGRVLEG ISKSISYDLD GEESYGKYLR
130 140 150 160 170 180
RESHQIGDAY SNSDKSLTEL ESKFKQGQEQ DSRQESRLNE DFLGMLVHTR SLLKETLDIS
190 200 210
VGLRDKYELL AHTIRSHGTR LGRLKSDYLE GGAQKTG