A4UZ23

PR
Gene name
FIBIN
Protein name
Fin bud initiation factor homolog
Names
Species
Equus caballus (Horse)
KEGG Pathway
ecb:100057578
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

33-189 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A4UZ23

Entry ID Method Resolution Chain Position Source
AF-A4UZ23-F1 Predicted AlphaFoldDB

No variants for A4UZ23

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A4UZ23

No associated diseases with A4UZ23

2 regional properties for A4UZ23

Type Name Position InterPro Accession
domain FKBP-type peptidyl-prolyl cis-trans isomerase domain 329 - 418 IPR001179
domain Nucleoplasmin-like domain 11 - 178 IPR041232

Functions

Description
EC Number
Subcellular Localization
  • Secreted
  • Golgi apparatus
  • Endoplasmic reticulum
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
endoplasmic reticulum The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
extracellular region The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
Golgi apparatus A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

4 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q5E9H1 FIBIN Fin bud initiation factor homolog Bos taurus (Bovine) PR
Q8TAL6 FIBIN Fin bud initiation factor homolog Homo sapiens (Human) PR
Q9CQS3 Fibin Fin bud initiation factor homolog Mus musculus (Mouse) PR
A1IGX5 fibin Fin bud initiation factor Danio rerio (Zebrafish) (Brachydanio rerio) PR
10 20 30 40 50 60
MVFLKFLWMG FFCYLCQGYF DGPLYPEMSN GTLHHYFVPD GDYEENDDPE KCQLLFRVSD
70 80 90 100 110 120
HRRCSQGEGS QASSLLSLTL REEFTVLGRQ VEDAGRVLEG ISKSISYDLD GEESYGKYLR
130 140 150 160 170 180
RESHQIGDAY SNSDKSLTEL ESKFKQGQEQ DSRQESRLNE DFLGMLVHTR SLLKETLDIS
190 200 210
AGLRDKYELL ALTIRSHGTR LGRLKNDYLK V