A1IGX5
Gene name |
fibin (zgc:110676) |
Protein name |
Fin bud initiation factor |
Names |
|
Species |
Danio rerio (Zebrafish) (Brachydanio rerio) |
KEGG Pathway |
dre:550571 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A1IGX5
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A1IGX5-F1 | Predicted | AlphaFoldDB |
No variants for A1IGX5
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for A1IGX5 | |||||
No associated diseases with A1IGX5
No regional properties for A1IGX5
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for A1IGX5 | |||
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| endoplasmic reticulum | The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached). |
| extracellular region | The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. |
| Golgi apparatus | A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| embryonic pectoral fin morphogenesis | The process, occurring in the embryo, by which the anatomical structures of the pectoral fin are generated and organized. Pectoral fins are bilaterally paired fins mounted laterally and located behind the gill covers of fish. These fins are used for lateral mobility and propulsion. |
4 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q5E9H1 | FIBIN | Fin bud initiation factor homolog | Bos taurus (Bovine) | PR |
| A4UZ23 | FIBIN | Fin bud initiation factor homolog | Equus caballus (Horse) | PR |
| Q8TAL6 | FIBIN | Fin bud initiation factor homolog | Homo sapiens (Human) | PR |
| Q9CQS3 | Fibin | Fin bud initiation factor homolog | Mus musculus (Mouse) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MGTMASPLFI | LIACLLSMRV | GGAFFAGPLY | PEMSNGTFHH | YFVPDGYYEE | NDDPEKCQML |
| 70 | 80 | 90 | 100 | 110 | 120 |
| FKMMDNRKCT | LDEDQDSVIR | DDFTIIKRHI | EDAARVLEGI | GKSISFDLDG | EDSYGKYLRR |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ETTQISEAFS | NSEKSLLELE | VKFKQSQENE | LKEEHKISDD | FLNMIVHTRD | VLKETLDISL |
| 190 | 200 | ||||
| GLKDKHELLS | LIIRSHGTRL | SRLKNDYMKV |