Q9C5P7
Gene name |
SEC1A (At1g02010, F22M8.14, T7I23.1) |
Protein name |
Protein transport Sec1a |
Names |
AtSec1a |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT1G02010 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9C5P7
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9C5P7-F1 | Predicted | AlphaFoldDB |
36 variants for Q9C5P7
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_1_348228_G_A | 33 | M>I | No | 1000Genomes | |
| tmp_1_348769_G_A | 112 | E>K | No | 1000Genomes | |
| tmp_1_348920_G_A | 131 | V>I | No | 1000Genomes | |
| ENSVATH00001730 | 185 | H>N | No | 1000Genomes | |
| tmp_1_349314_T_C | 186 | I>T | No | 1000Genomes | |
| ENSVATH10453690 | 189 | N>D | No | 1000Genomes | |
| ENSVATH04505379 | 262 | A>T | No | 1000Genomes | |
| ENSVATH13848846 | 288 | E>G | No | 1000Genomes | |
| tmp_1_350080_A_T | 299 | K>I | No | 1000Genomes | |
| tmp_1_350081_A_T | 299 | K>N | No | 1000Genomes | |
| tmp_1_350229_A_G | 323 | S>G | No | 1000Genomes | |
| ENSVATH13848847 | 328 | E>Q | No | 1000Genomes | |
| ENSVATH00001739 | 351 | S>C | No | 1000Genomes | |
| ENSVATH10453835 | 353 | R>L | No | 1000Genomes | |
| tmp_1_350507_G_T | 356 | Q>H | No | 1000Genomes | |
| ENSVATH04505386 | 357 | K>R | No | 1000Genomes | |
| tmp_1_350560_C_T | 374 | T>I | No | 1000Genomes | |
| ENSVATH01003354 | 425 | N>T | No | 1000Genomes | |
| tmp_1_350919_G_A | 436 | V>M | No | 1000Genomes | |
| tmp_1_351110_G_A | 474 | E>K | No | 1000Genomes | |
| ENSVATH04505395 | 495 | N>I | No | 1000Genomes | |
| tmp_1_351430_G_T | 523 | V>L | No | 1000Genomes | |
| tmp_1_351439_G_A | 526 | D>N | No | 1000Genomes | |
| ENSVATH04505397 | 554 | S>N | No | 1000Genomes | |
| ENSVATH04505398 | 558 | T>I | No | 1000Genomes | |
| tmp_1_351535_A_T | 558 | T>S | No | 1000Genomes | |
| tmp_1_351590_C_G | 576 | A>G | No | 1000Genomes | |
| ENSVATH10453839 | 578 | W>L | No | 1000Genomes | |
| ENSVATH00001746 | 581 | P>L | No | 1000Genomes | |
| tmp_1_351614_C_G | 584 | S>C | No | 1000Genomes | |
| tmp_1_351623_G_A | 587 | G>E | No | 1000Genomes | |
| ENSVATH04505402 | 599 | T>M | No | 1000Genomes | |
| tmp_1_351924_C_G | 625 | H>D | No | 1000Genomes | |
| ENSVATH04505406 | 643 | D>V | No | 1000Genomes | |
| ENSVATH04505408 | 656 | S>L | No | 1000Genomes | |
| tmp_1_352141_T_C | 656 | S>P | No | 1000Genomes |
No associated diseases with Q9C5P7
No regional properties for Q9C5P7
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q9C5P7 | |||
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
| secretory granule | A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell and upon stimulation, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| syntaxin binding | Binding to a syntaxin, a SNAP receptor involved in the docking of synaptic vesicles at the presynaptic zone of a synapse. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| intracellular protein transport | The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell. |
| vesicle docking involved in exocytosis | The initial attachment of a vesicle membrane to a target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane, that contributes to exocytosis. |
| vesicle-mediated transport | A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane. |
6 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P30619 | SEC1 | Protein transport protein SEC1 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| Q15833 | STXBP2 | Syntaxin-binding protein 2 | Homo sapiens (Human) | PR |
| Q64324 | Stxbp2 | Syntaxin-binding protein 2 | Mus musculus (Mouse) | PR |
| O08599 | Stxbp1 | Syntaxin-binding protein 1 | Mus musculus (Mouse) | PR |
| Q62753 | Stxbp2 | Syntaxin-binding protein 2 | Rattus norvegicus (Rat) | PR |
| Q5VNU3 | Os06g0135900 | Probable protein transport Sec1b | Oryza sativa subsp japonica (Rice) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSFSDSESSS | HGGGGGDYKF | FRQISRDRLL | HEMLGSTKTG | DSKAWKILIM | DRVTVKVMSQ |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SCKMADITDQ | GISLVEELFK | RREPMPGMDA | IYFIQPSKEN | IVMFLSDMSG | REPLYRKAFI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| FFSSTIPKEL | VNHIKSDSSV | LPRIGALREM | NMEYFPIDNQ | GFLTDHEQAL | ETLYAEDAEN |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SRHFHICLNI | MATRIATVFA | SLKELPFVRY | RAAKSTASRD | LVPSKLAAAI | WDCISKYKAI |
| 250 | 260 | 270 | 280 | 290 | 300 |
| PNFPQTETCE | LLIVDRSVDQ | IAPIIHEWTY | DAMCHDLLDM | EGNKHVIEVP | SKTGGPPEKK |
| 310 | 320 | 330 | 340 | 350 | 360 |
| EIVLEDHDPV | WLELRHTHIA | DASERLHEKM | TNFASKNKAA | QMRSRDGSEL | STRDLQKIVQ |
| 370 | 380 | 390 | 400 | 410 | 420 |
| ALPQYGEQVD | KLSTHVELAG | KINRIIRDTG | LRDLGQLEQD | LVFGDAGAKD | VINFLRTNQD |
| 430 | 440 | 450 | 460 | 470 | 480 |
| TNPENKLRLL | MIYATVYPEK | FEGDKGVKLM | QLARLSPVDM | KVISNMQLIA | GSPENKAKSG |
| 490 | 500 | 510 | 520 | 530 | 540 |
| SFSLKFDAGK | TKQANRKDRS | GEEETWQLFR | FYPMIEELLE | KLVKGDLSKS | DYLCMNQSSH |
| 550 | 560 | 570 | 580 | 590 | 600 |
| KEESEARTGS | VRKSSAPTAV | PERKATPHSM | RSRRTATWAR | PHSSDDGYSS | DSVLKSASTE |
| 610 | 620 | 630 | 640 | 650 | 660 |
| FKKLGQRIFV | FIIGGATRSE | LRVCHKLTSS | LRREVVLGST | SFDDPPQYIT | KLKLLSEKDI |
| 670 | |||||
| QGAPAQPFKP | QYW |