Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
2 structures for Q95747
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 6XYW | EM | 386 A | Am | 1-179 | PDB |
| AF-Q95747-F1 | Predicted | AlphaFoldDB |
No variants for Q95747
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q95747 | |||||
No associated diseases with Q95747
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| mitochondrial large ribosomal subunit | The larger of the two subunits of a mitochondrial ribosome. Two sites on the ribosomal large subunit are involved in translation: the aminoacyl site (A site) and peptidyl site (P site). |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| rRNA binding | Binding to a ribosomal RNA. |
| structural constituent of ribosome | The action of a molecule that contributes to the structural integrity of the ribosome. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| mitochondrial translation | The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the mitochondrion has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code. |
3 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P38064 | MRPL16 | 54S ribosomal protein L16, mitochondrial | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| Q3T0J3 | MRPL16 | 39S ribosomal protein L16, mitochondrial | Bos taurus (Bovine) | PR |
| Q5M818 | Mrpl16 | 39S ribosomal protein L16, mitochondrial | Rattus norvegicus (Rat) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MYLTIKSIML | LWKYLLVTES | QVSKCGFHIV | KKKGDVLYPK | RTKYSKYRKG | RCSRGCKPDG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| TKLGFGRYGI | KSCKAGCLSY | RAIEAARRAI | IGHFHRAMSG | QFRRNGKIWV | RVFADLPITG |
| 130 | 140 | 150 | 160 | 170 | |
| KPTEVRMGRG | KGNPTGWIAR | VSTGQILFEM | DGVSLANARQ | AATLAAHKLC | LSTKFVQWS |