Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

2 structures for Q95747

Entry ID Method Resolution Chain Position Source
6XYW EM 386 A Am 1-179 PDB
AF-Q95747-F1 Predicted AlphaFoldDB

No variants for Q95747

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q95747

No associated diseases with Q95747

2 regional properties for Q95747

Type Name Position InterPro Accession
domain Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain 172 - 293 IPR019564
domain Metaxin, glutathione S-transferase domain 323 - 386 IPR033468

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
mitochondrial large ribosomal subunit The larger of the two subunits of a mitochondrial ribosome. Two sites on the ribosomal large subunit are involved in translation: the aminoacyl site (A site) and peptidyl site (P site).

2 GO annotations of molecular function

Name Definition
rRNA binding Binding to a ribosomal RNA.
structural constituent of ribosome The action of a molecule that contributes to the structural integrity of the ribosome.

1 GO annotations of biological process

Name Definition
mitochondrial translation The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the mitochondrion has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code.

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P38064 MRPL16 54S ribosomal protein L16, mitochondrial Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PR
Q3T0J3 MRPL16 39S ribosomal protein L16, mitochondrial Bos taurus (Bovine) PR
Q5M818 Mrpl16 39S ribosomal protein L16, mitochondrial Rattus norvegicus (Rat) PR
10 20 30 40 50 60
MYLTIKSIML LWKYLLVTES QVSKCGFHIV KKKGDVLYPK RTKYSKYRKG RCSRGCKPDG
70 80 90 100 110 120
TKLGFGRYGI KSCKAGCLSY RAIEAARRAI IGHFHRAMSG QFRRNGKIWV RVFADLPITG
130 140 150 160 170
KPTEVRMGRG KGNPTGWIAR VSTGQILFEM DGVSLANARQ AATLAAHKLC LSTKFVQWS