Q5M818
Gene name |
Mrpl16 |
Protein name |
39S ribosomal protein L16, mitochondrial |
Names |
L16mt, MRP-L16 |
Species |
Rattus norvegicus (Rat) |
KEGG Pathway |
rno:293754 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q5M818
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q5M818-F1 | Predicted | AlphaFoldDB |
1 variants for Q5M818
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs3319183501 | 217 | R>H | No | EVA |
No associated diseases with Q5M818
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| mitochondrial large ribosomal subunit | The larger of the two subunits of a mitochondrial ribosome. Two sites on the ribosomal large subunit are involved in translation: the aminoacyl site (A site) and peptidyl site (P site). |
| mitochondrial small ribosomal subunit | The smaller of the two subunits of a mitochondrial ribosome. |
| mitochondrion | A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| rRNA binding | Binding to a ribosomal RNA. |
| structural constituent of ribosome | The action of a molecule that contributes to the structural integrity of the ribosome. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| mitochondrial translation | The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the mitochondrion has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code. |
5 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P38064 | MRPL16 | 54S ribosomal protein L16, mitochondrial | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| Q3T0J3 | MRPL16 | 39S ribosomal protein L16, mitochondrial | Bos taurus (Bovine) | PR |
| A7MB75 | TMEM231 | Transmembrane protein 231 | Bos taurus (Bovine) | PR |
| Q9H6L2 | TMEM231 | Transmembrane protein 231 | Homo sapiens (Human) | PR |
| Q95747 | RPL16 | 60S ribosomal protein L16, mitochondrial | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MWRLLTRAPA | PLWRMHFSDT | WAALPTSAGL | KTLLPVPTFE | NVSIPERSKL | KFVERVPLVP |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KVRREPKNLK | DIRGPSAEAT | DFTEGNFAIL | ALGGGYLHWG | HFEMMRLTIN | RFMDPKNMFA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| IWRVPAPFKP | ITRKGVGQRM | GGGKGAIDHY | VTPVKTGCLI | VEMGGRCEFE | EVKRVLNQVA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| HKLPFPAKAV | SRKTLEKMHQ | NQKERELNNQ | NPWTFERIAT | ANMFGIRKFL | SPYDLTQKGR |
| 250 | |||||
| YWGKFYMPKR | V |