Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q940B0

Entry ID Method Resolution Chain Position Source
AF-Q940B0-F1 Predicted AlphaFoldDB

9 variants for Q940B0

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH14264210 2 G>A No 1000Genomes
ENSVATH14264455 72 T>N No 1000Genomes
ENSVATH11182123 95 P>A No 1000Genomes
ENSVATH14264456 110 A>D No 1000Genomes
tmp_5_9873976_G_A 110 A>T No 1000Genomes
tmp_5_9874008_A_T 120 L>F No 1000Genomes
ENSVATH11182245 128 R>I No 1000Genomes
tmp_5_9874139_G_A 136 V>I No 1000Genomes
tmp_5_9874217_A_T 162 T>S No 1000Genomes

No associated diseases with Q940B0

1 regional properties for Q940B0

Type Name Position InterPro Accession
domain Ribosomal protein L18e/L15P 2 - 188 IPR021131

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

5 GO annotations of cellular component

Name Definition
cytosolic large ribosomal subunit The large subunit of a ribosome located in the cytosol.
cytosolic ribosome A ribosome located in the cytosol.
plasmodesma A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.
plastid Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid.
vacuole A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.

3 GO annotations of molecular function

Name Definition
mRNA binding Binding to messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
RNA binding Binding to an RNA molecule or a portion thereof.
structural constituent of ribosome The action of a molecule that contributes to the structural integrity of the ribosome.

1 GO annotations of biological process

Name Definition
translation The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.

4 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q07020 RPL18 60S ribosomal protein L18 Homo sapiens (Human) PR
P35980 Rpl18 60S ribosomal protein L18 Mus musculus (Mouse) PR
O22254 RPL18A Putative 60S ribosomal protein L18-1 Arabidopsis thaliana (Mouse-ear cress) PR
P42791 RPL18B 60S ribosomal protein L18-2 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MGIDLIAGGK SKKTKRTAPK SDDVYLKLLV KLYRFLVRRS NSNFNAVILK RLFMSKVNKA
70 80 90 100 110 120
PLSLSRLVEF MTGKDDKIAV LVGTITDDLR VHEIPAMKVT ALRFTERARA RIEKAGGECL
130 140 150 160 170 180
TFDQLALRAP LGQNTVLLRG PKNSREAVKH FGPAPGVPHS NTKPYVRHKG RKFEKARGKR
KSRGFKV