P42791
Gene name |
RPL18B (At3g05590, F18C1.14) |
Protein name |
60S ribosomal protein L18-2 |
Names |
|
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT3G05590 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P42791
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P42791-F1 | Predicted | AlphaFoldDB |
8 variants for P42791
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_3_1621832_A_G | 15 | K>R | No | 1000Genomes | |
| tmp_3_1622022_A_G | 41 | N>S | No | 1000Genomes | |
| ENSVATH13874076 | 46 | G>C | No | 1000Genomes | |
| tmp_3_1622057_T_C | 53 | F>L | No | 1000Genomes | |
| tmp_3_1622349_T_A | 76 | D>E | No | 1000Genomes | |
| tmp_3_1622423_C_G | 101 | A>G | No | 1000Genomes | |
| ENSVATH13874077 | 140 | G>R | No | 1000Genomes | |
| tmp_3_1622735_A_T | 175 | K>M | No | 1000Genomes |
No associated diseases with P42791
1 regional properties for P42791
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Ribosomal protein L18e/L15P | 2 - 187 | IPR021131 |
6 GO annotations of cellular component
| Name | Definition |
|---|---|
| chloroplast | A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma. |
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| cytosolic large ribosomal subunit | The large subunit of a ribosome located in the cytosol. |
| large ribosomal subunit | The larger of the two subunits of a ribosome. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). |
| plant-type vacuole | A closed structure that is completely surrounded by a unit membrane, contains liquid, and retains the same shape regardless of cell cycle phase. An example of this structure is found in Arabidopsis thaliana. |
| vacuole | A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| mRNA binding | Binding to messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns. |
| RNA binding | Binding to an RNA molecule or a portion thereof. |
| structural constituent of ribosome | The action of a molecule that contributes to the structural integrity of the ribosome. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| translation | The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome. |
4 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q07020 | RPL18 | 60S ribosomal protein L18 | Homo sapiens (Human) | PR |
| P35980 | Rpl18 | 60S ribosomal protein L18 | Mus musculus (Mouse) | PR |
| O22254 | RPL18A | Putative 60S ribosomal protein L18-1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q940B0 | RPL18C | 60S ribosomal protein L18-3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MGIDLIAGGK | SKKTKRTAPK | SDDVYLKLTV | KLYRFLVRRT | NSKFNGVILK | RLFMSKVNKA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| PLSLSRLVEF | MTGKEDKIAV | LVGTITDDLR | VHEIPAMKVT | ALRFTERARA | RIEKAGGECL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| TFDQLALRAP | LGQNTVLLRG | PKNSREAVKH | FGPAPGVPHS | HSKPYVRAKG | RKFEKARGKR |
| KSRGFKV |