O22254

PR
Gene name
RPL18A (At2g47570, T30B22.13)
Protein name
Putative 60S ribosomal protein L18-1
Names
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT2G47570
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-49 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O22254

Entry ID Method Resolution Chain Position Source
AF-O22254-F1 Predicted AlphaFoldDB

No variants for O22254

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O22254

No associated diseases with O22254

1 regional properties for O22254

Type Name Position InterPro Accession
domain Ribosomal protein L18e/L15P 2 - 188 IPR021131

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosolic large ribosomal subunit The large subunit of a ribosome located in the cytosol.

3 GO annotations of molecular function

Name Definition
mRNA binding Binding to messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
RNA binding Binding to an RNA molecule or a portion thereof.
structural constituent of ribosome The action of a molecule that contributes to the structural integrity of the ribosome.

1 GO annotations of biological process

Name Definition
translation The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.

4 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q07020 RPL18 60S ribosomal protein L18 Homo sapiens (Human) PR
P35980 Rpl18 60S ribosomal protein L18 Mus musculus (Mouse) PR
P42791 RPL18B 60S ribosomal protein L18-2 Arabidopsis thaliana (Mouse-ear cress) PR
Q940B0 RPL18C 60S ribosomal protein L18-3 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MGIDLIAGGK SKKTKRTEPK SDDVYLKLLV KANRYLVRRT ESKFNAVILK RLFMSKVNKA
70 80 90 100 110 120
PLSLSRLVRY MDGKDGKIAV IVGTVTDDVR IEDVPALTVT ALRFTESARA RIHKAGGECL
130 140 150 160 170 180
TFDQLALPCP TWSENTVLLR GPKNTREAVK HFGPAPGVPH SHTKPYVRQT GKKIEIARGR
RRSRGFKV