AiPD: Autoinhibited Protein Database

Gene name	MDAR2
Protein name	Monodehydroascorbate reductase 2
Names	AtMDAR2
Species	Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway	ath:AT5G03630
EC number	1.6.5.4: With a quinone or similar compound as acceptor
Protein Class

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

375-435 (Predicted disordered autoinhibitory region) PR

375-435 (Predicted disordered autoinhibitory region)

cis-regPred

No accessory elements

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q93WJ8-F1	Predicted				AlphaFoldDB

Variant ID(s)	Position	Change	Diseaes Association	Provenance
ENSVATH03016795	4	E>Q	No	1000Genomes
ENSVATH03016793	17	A>T	No	1000Genomes
tmp_5_924011_T_G	73	I>L	No	1000Genomes
ENSVATH13904661	98	K>E	No	1000Genomes
ENSVATH10538326	103	A>T	No	1000Genomes
tmp_5_923620_T_C	143	I>V	No	1000Genomes
ENSVATH06916608	167	A>T	No	1000Genomes
tmp_5_923509_C_T	180	G>S	No	1000Genomes
tmp_5_923337_C_T	207	G>D	No	1000Genomes
ENSVATH06916605	219	K>R	No	1000Genomes
tmp_5_923275_C_T	228	V>I	No	1000Genomes
ENSVATH10538262	251	L>F	No	1000Genomes
ENSVATH10538261	252	E>K	No	1000Genomes
ENSVATH10538232	290	L>I	No	1000Genomes
tmp_5_922854_T_A	308	N>Y	No	1000Genomes
tmp_5_922842_G_A	312	R>C	No	1000Genomes
ENSVATH10538228	316	V>I	No	1000Genomes
ENSVATH08403393	325	Q>K	No	1000Genomes
ENSVATH10538221	373	N>Y	No	1000Genomes
tmp_5_922553_G_T	378	P>Q	No	1000Genomes
ENSVATH00604686	390	R>G	No	1000Genomes
ENSVATH00604685	401	S>T	No	1000Genomes
tmp_5_922455_G_C	411	L>V	No	1000Genomes
ENSVATH06916598	414	A>E	No	1000Genomes
ENSVATH06916597	422	E>Q	No	1000Genomes

Type	Name	Position	InterPro Accession
domain	Glycosyl transferase, family 1	297 - 464	IPR001296
domain	ALG11 mannosyltransferase, N-terminal	61 - 267	IPR031814

		Description
EC Number	1.6.5.4	With a quinone or similar compound as acceptor
Subcellular Localization	Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

Name	Definition
chloroplast stroma	The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis.
cytoplasm	The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
cytosol	The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
plasma membrane	The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

Name	Definition
flavin adenine dinucleotide binding	Binding to FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes, in either the oxidized form, FAD, or the reduced form, FADH2.
monodehydroascorbate reductase (NADH) activity	Catalysis of the reaction: NADH + H+ + 2 monodehydroascorbate = NAD+ + 2 ascorbate.
oxidoreductase activity, acting on NAD(P)H	Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.

Name	Definition
response to zinc ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus.

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
O95831	AIFM1	Apoptosis-inducing factor 1, mitochondrial	Homo sapiens (Human)	PR
Q96NN9	AIFM3	Apoptosis-inducing factor 3	Homo sapiens (Human)	PR
Q9Z0X1	Aifm1	Apoptosis-inducing factor 1, mitochondrial	Mus musculus (Mouse)	PR
Q3TY86	Aifm3	Apoptosis-inducing factor 3	Mus musculus (Mouse)	PR
Q9JM53	Aifm1	Apoptosis-inducing factor 1, mitochondrial	Rattus norvegicus (Rat)	PR
Q9SR59	MDAR3	Monodehydroascorbate reductase 3	Arabidopsis thaliana (Mouse-ear cress)	PR