Q921R8
Gene name |
Slc41a3 |
Protein name |
Solute carrier family 41 member 3 |
Names |
|
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:71699 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q921R8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q921R8-F1 | Predicted | AlphaFoldDB |
No variants for Q921R8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q921R8 | |||||
No associated diseases with Q921R8
2 regional properties for Q921R8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | SLC41A/MgtE, integral membrane domain | 106 - 239 | IPR006667-1 |
| domain | SLC41A/MgtE, integral membrane domain | 319 - 463 | IPR006667-2 |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| mitochondrial inner membrane | The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| magnesium:sodium antiporter activity | Catalysis of the reaction: Na+(in) + Mg2+(out) = Na+(out) + Mg2+(in). |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| mitochondrial magnesium ion transmembrane transport | The process in which a magnesium ion (Mg2+) is transported across a mitochondrial membrane, into or out of the mitochondrion. |
6 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q5ZHX6 | SLC41A2 | Solute carrier family 41 member 2 | Gallus gallus (Chicken) | PR |
| Q96JW4 | SLC41A2 | Solute carrier family 41 member 2 | Homo sapiens (Human) | PR |
| Q8IVJ1 | SLC41A1 | Solute carrier family 41 member 1 | Homo sapiens (Human) | PR |
| Q8BYR8 | Slc41a2 | Solute carrier family 41 member 2 | Mus musculus (Mouse) | PR |
| Q8BJA2 | Slc41a1 | Solute carrier family 41 member 1 | Mus musculus (Mouse) | PR |
| Q3SWT5 | Slc41a3 | Solute carrier family 41 member 3 | Rattus norvegicus (Rat) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEGTEARQRR | LEGCGRLKEL | GPLPSHDAGR | LPKASEEGHL | AVSESQLVDA | KSLEAPPGRE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| TSLIIGFQVV | IPFLLAGVGL | SWAGLLLNYF | QHWPVFKDVK | DLMTLVPPLV | GLKGNLEMTL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ASRLSTSANT | GQIDDRQERY | KIISSNLAVV | QVQATVVGLL | AAVASLMLGT | VSHEEFDWSK |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VALLCTSSVI | TAFLAALALG | ILMICIVIGA | RKFGVNPDNI | ATPIAASLGD | LITLSILALM |
| 250 | 260 | 270 | 280 | 290 | 300 |
| SSFFYSHKDT | WYLTPLVCVG | FLALTPLWLF | IAKQNPPIMK | ILKYGWFPII | LAMIISSFGG |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LILSKTISKH | EFKGMAVLTP | VMCGVGGNLV | AIQTSRISTF | LHMWSTPGVL | PVQMKRFWPN |
| 370 | 380 | 390 | 400 | 410 | 420 |
| PCFIFCSSEI | NSVSARVLLF | LVVPGHLIFF | YLICLVEGQS | VTNSKIFILL | YLVAGVVQVV |
| 430 | 440 | 450 | 460 | 470 | 480 |
| ILLYLAEVTV | RLTWHQALDP | DNHCIPYLTG | LGDLLGTSLL | ALCFFLDWLL | RGRANLQELV |
| SELVSVPP |