Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q5ZHX6

Entry ID Method Resolution Chain Position Source
AF-Q5ZHX6-F1 Predicted AlphaFoldDB

No variants for Q5ZHX6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5ZHX6

No associated diseases with Q5ZHX6

2 regional properties for Q5ZHX6

Type Name Position InterPro Accession
domain SLC41A/MgtE, integral membrane domain 200 - 333 IPR006667-1
domain SLC41A/MgtE, integral membrane domain 414 - 555 IPR006667-2

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

1 GO annotations of molecular function

Name Definition
cation transmembrane transporter activity Enables the transfer of cation from one side of a membrane to the other.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

6 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q8IVJ1 SLC41A1 Solute carrier family 41 member 1 Homo sapiens (Human) PR
Q96JW4 SLC41A2 Solute carrier family 41 member 2 Homo sapiens (Human) PR
Q921R8 Slc41a3 Solute carrier family 41 member 3 Mus musculus (Mouse) PR
Q8BJA2 Slc41a1 Solute carrier family 41 member 1 Mus musculus (Mouse) PR
Q8BYR8 Slc41a2 Solute carrier family 41 member 2 Mus musculus (Mouse) PR
Q3SWT5 Slc41a3 Solute carrier family 41 member 3 Rattus norvegicus (Rat) PR
10 20 30 40 50 60
MTNCKGRSTI TKTNSKVHDR EGFVNWTISL STVQSDKFLN LLLSMVPVVY QINQDERHKK
70 80 90 100 110 120
VNGVWQDGLQ PAGHNYNVKS DQHVEYHHFS EQTFHGSNGH SPSSCSPKYD DFSSYNYCDG
130 140 150 160 170 180
MDASETDAML QEDNISSDSN EDIIVEGIRK QPKESSSIMA LQILVPFLLA GFGTVTAGMV
190 200 210 220 230 240
LDIVQHWDVF KNVTEVFILV PALLGLKGNL EMTLASRLST AVNIGKMDSP IEKWNLIIGN
250 260 270 280 290 300
LALKQVQATV VGFLAAVAAV ILGWIPEGKY SFSHSILLCS SSVATAFIAS LLQGIIMVGV
310 320 330 340 350 360
IVGSKKTGIN PDNVATPIAA SFGDLITLAI LAWISQGLYT CLETYYYVSP LVGAFFLALT
370 380 390 400 410 420
PMGIVIAAKH PATRTVLHSG WEPVITAMII SSIGGLILDT TVSDPNLVGI VVYTPVINGI
430 440 450 460 470 480
GGNLVAIQAS RISTYLHLHS IPGELPEEAK GCYYPCRTYY GTGVNNKSAQ VLLLLVIPGH
490 500 510 520 530 540
LIFLYTIHLM KSGHTSLTPI FIAVYLFAAL LQVFTLLWIA DWMVHHFWKK GKDPDSFSIP
550 560 570
YLTALGDLLG TALLAVGFHF LWLIGDRDGD VGD