Q8W3D0

PR
Gene name
PDX12 (Os10g0100700, LOC_Os10g01080, OJ1136E01.11, OSJNBa0046L02.5)
Protein name
Probable pyridoxal 5'-phosphate synthase subunit PDX1.2
Names
PLP synthase subunit PDX1.2
Species
Oryza sativa subsp japonica (Rice)
KEGG Pathway
osa:4347937
EC number
4.3.3.6: Amine-lyases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-50 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8W3D0

Entry ID Method Resolution Chain Position Source
AF-Q8W3D0-F1 Predicted AlphaFoldDB

No variants for Q8W3D0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8W3D0

No associated diseases with Q8W3D0

No regional properties for Q8W3D0

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q8W3D0

Functions

Description
EC Number 4.3.3.6 Amine-lyases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
amine-lyase activity Catalysis of the release of amines by the cleavage of a carbon-nitrogen bond or the reverse reaction with an amine as a substrate.
pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity Catalysis of the reaction: D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + L-glutamine = pyridoxal 5'-phosphate + L-glutamate + 3 H2O + phosphate. The reaction occurs in two steps: L-glutamine + H2O = L-glutamate + NH3, and subsequently D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + NH3 = pyridoxal 5'-phosphate + 4 H2O + phosphate.

3 GO annotations of biological process

Name Definition
cellular amino acid metabolic process The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups, as carried out by individual cells.
pyridoxal phosphate biosynthetic process The chemical reactions and pathways resulting in the formation of pyridoxal phosphate, pyridoxal phosphorylated at the hydroxymethyl group of C-5, the active form of vitamin B6.
pyridoxine biosynthetic process The chemical reactions and pathways resulting in the formation of pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, one of the vitamin B6 compounds.

4 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P53824 SNZ2 Probable pyridoxal 5'-phosphate synthase subunit SNZ2 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PR
P43545 SNZ3 Probable pyridoxal 5'-phosphate synthase subunit SNZ3 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PR
Q69LA6 PDX11 Probable pyridoxal 5'-phosphate synthase subunit PDX1.1 Oryza sativa subsp japonica (Rice) PR
O80448 PDX11 Pyridoxal 5'-phosphate synthase subunit PDX1.1 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MASDGTDVVA LYGGANGLSH KSGSFSVKVG LAQMLRGGVI MDVVTPEQAR IAEEAGACAV
70 80 90 100 110 120
MALERVPADI RAQGGVARMS DPGLIRDIKR SVTIPVMAKA RIGHLVEAQI LEAIGVDYVD
130 140 150 160 170 180
ESEVLTLADD AHHINKNNFR VPFVCGCRDL GEALRRIREG AAMIRTKGEA GTGNVVEAVR
190 200 210 220 230 240
HVRSVMGDIR ALRSMDDDEV FSYAKRIAAP YDLVMQTKQL GRLPVVQFAA GGVATPADAA
250 260 270 280 290 300
LMMQLGCDGV FVGSGIFKSG DPALRARAIV QAVTHYSDPK ILAEVSSGLG EAMVGINLSD
310
PKIHVERFAA RSD