Q69LA6

PR
Gene name
PDX11 (Os07g0100200, LOC_Os07g01020, B1026C12.3, OSJNOa219C16.3)
Protein name
Probable pyridoxal 5'-phosphate synthase subunit PDX1.1
Names
PLP synthase subunit PDX1.1
Species
Oryza sativa subsp japonica (Rice)
KEGG Pathway
osa:4342162
EC number
4.3.3.6: Amine-lyases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-56 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q69LA6

Entry ID Method Resolution Chain Position Source
AF-Q69LA6-F1 Predicted AlphaFoldDB

No variants for Q69LA6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q69LA6

No associated diseases with Q69LA6

1 regional properties for Q69LA6

Type Name Position InterPro Accession
domain PdxS/SNZ N-terminal domain 32 - 237 IPR033755

Functions

Description
EC Number 4.3.3.6 Amine-lyases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
amine-lyase activity Catalysis of the release of amines by the cleavage of a carbon-nitrogen bond or the reverse reaction with an amine as a substrate.
pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity Catalysis of the reaction: D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + L-glutamine = pyridoxal 5'-phosphate + L-glutamate + 3 H2O + phosphate. The reaction occurs in two steps: L-glutamine + H2O = L-glutamate + NH3, and subsequently D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + NH3 = pyridoxal 5'-phosphate + 4 H2O + phosphate.

3 GO annotations of biological process

Name Definition
cellular amino acid metabolic process The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups, as carried out by individual cells.
pyridoxal phosphate biosynthetic process The chemical reactions and pathways resulting in the formation of pyridoxal phosphate, pyridoxal phosphorylated at the hydroxymethyl group of C-5, the active form of vitamin B6.
pyridoxine biosynthetic process The chemical reactions and pathways resulting in the formation of pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, one of the vitamin B6 compounds.

4 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P53824 SNZ2 Probable pyridoxal 5'-phosphate synthase subunit SNZ2 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PR
P43545 SNZ3 Probable pyridoxal 5'-phosphate synthase subunit SNZ3 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PR
Q8W3D0 PDX12 Probable pyridoxal 5'-phosphate synthase subunit PDX1.2 Oryza sativa subsp japonica (Rice) PR
O80448 PDX11 Pyridoxal 5'-phosphate synthase subunit PDX1.1 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MATDGTGVVT VYGSGTNGAA LLEPSNHKSA TFSVKVGLAQ MLRGGVIMDV VTPEQARIAE
70 80 90 100 110 120
EAGACAVMAL ERVPADIRAQ GGVARMSDPG LIRDIKRAVT IPVMAKARIG HFVEAQILEA
130 140 150 160 170 180
IGVDYVDESE VLTLADDAHH INKHNFRVPF VCGCRDLGEA LRRIREGAAM IRTKGEAGTG
190 200 210 220 230 240
NVVEAVRHVR SVMGDIRALR NMDDDEVFSY AKRIAAPYDL VMQTKQLGRL PVVQFAAGGV
250 260 270 280 290 300
ATPADAALMM QLGCDGVFVG SGIFKSGDPA RRARAIVQAV THYSDPKILA EVSSGLGEAM
310
VGINLSDPKV ERFAARSE