Q8BXN9

PR
Gene name
Tmem87a
Protein name
Transmembrane protein 87A
Names
Species
Mus musculus (Mouse)
KEGG Pathway
mmu:211499
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

440-555 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8BXN9

Entry ID Method Resolution Chain Position Source
AF-Q8BXN9-F1 Predicted AlphaFoldDB

No variants for Q8BXN9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8BXN9

No associated diseases with Q8BXN9

No regional properties for Q8BXN9

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q8BXN9

Functions

Description
EC Number
Subcellular Localization
  • [Isoform 1]: Cell membrane ; Multi-pass membrane protein
  • Golgi apparatus membrane ; Multi-pass membrane protein
  • ;
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

6 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
Golgi apparatus A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways.
Golgi cisterna membrane The lipid bilayer surrounding any of the thin, flattened compartments that form the central portion of the Golgi complex.
Golgi membrane The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
retrograde transport, endosome to Golgi The directed movement of membrane-bounded vesicles from endosomes back to the trans-Golgi network where they are recycled for further rounds of transport.

5 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q96K49 TMEM87B Transmembrane protein 87B Homo sapiens (Human) PR
Q8NBN3 TMEM87A Transmembrane protein 87A Homo sapiens (Human) PR
Q8BKU8 Tmem87b Transmembrane protein 87B Mus musculus (Mouse) PR
Q91WD0 Gpr108 Protein GPR108 Mus musculus (Mouse) PR
Q28EW0 tmem87a Transmembrane protein 87A Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) PR
10 20 30 40 50 60
MAVAAWLQVS PVIFLLLGAQ PFPLSFLGAG PAPVFAADRS KWHIPMPSGK GYFNFGKILF
70 80 90 100 110 120
RNTTILLKFD GEPCDQSLNI TWFLKSADCY NEIYNFKADE IESYLENLKG KKGLSGRYQT
130 140 150 160 170 180
SSRLFQNCSE LYKAQSFSGD FTHRLPLLGE KQEAKENATN VTFTGDKIAM HEPLQTWQDA
190 200 210 220 230 240
PYIFIVHVGI SSSKESPKEN ALSNLFTMTV EVKGPYEYLT LEDYPLMIFF MVMCIVYVLF
250 260 270 280 290 300
GVLWLAWSAC YWRDLLRIQF WIGAVIFLGM FEKAVFYAEF QNIRYKGESV QNALVLAELL
310 320 330 340 350 360
SAVKRSLART LVIIVSLGYG IVKPRLGVTL HKVVVAGALY LLFSGMEGVL RVTGAQTDLA
370 380 390 400 410 420
SLAFIPLAFL DTALCWWIFI SLTQTMKLLK LRRNIVKLSL YRHFTNTLIL AVAASIVFII
430 440 450 460 470 480
WTTMKFRIVT CQSDWRELWV DDAIWRLLFS MILFVIMILW RPSANNQRFA FSPLSEEDEE
490 500 510 520 530 540
DEQKEPMLKE SFEGMKMRST KQEPNGTSKV NKAQEDDLKW VEENVPSSVT DVALPALLDS
550
DEERMITHFE RSKME