Q8BKU8
Gene name |
Tmem87b |
Protein name |
Transmembrane protein 87B |
Names |
|
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:72477 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8BKU8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8BKU8-F1 | Predicted | AlphaFoldDB |
29 variants for Q8BKU8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs3388593976 | 6 | R>L | No | EVA | |
| rs3388590390 | 9 | A>D | No | EVA | |
| rs29506089 | 14 | S>G | No | EVA | |
| rs3388590411 | 150 | L>S | No | EVA | |
| rs3388583166 | 175 | Q>P | No | EVA | |
| rs3388583120 | 181 | I>N | No | EVA | |
| rs1133952332 | 236 | L>Q | No | EVA | |
| rs1132556881 | 237 | L>M | No | EVA | |
| rs1132877753 | 238 | W>R | No | EVA | |
| rs1133684281 | 239 | S>T | No | EVA | |
| rs1132158685 | 240 | A>V | No | EVA | |
| rs3392191304 | 251 | F>I | No | EVA | |
| rs3392066800 | 251 | F>Y | No | EVA | |
| rs3388590273 | 283 | G>V | No | EVA | |
| rs3388583184 | 366 | F>C | No | EVA | |
| rs3392192941 | 388 | V>M | No | EVA | |
| rs3392221084 | 390 | F>I | No | EVA | |
| rs3388589702 | 392 | L>F | No | EVA | |
| rs3388583412 | 396 | F>Y | No | EVA | |
| rs1132377568 | 397 | T>K | No | EVA | |
| rs1133170218 | 398 | N>K | No | EVA | |
| rs3388589785 | 405 | L>Q | No | EVA | |
| rs3388590125 | 409 | V>L | No | EVA | |
| rs3388584325 | 410 | F>C | No | EVA | |
| rs3392231384 | 504 | T>P | No | EVA | |
| rs1133962317 | 507 | N>D | No | EVA | |
| rs3388584310 | 537 | E>D | No | EVA | |
| rs3388577405 | 538 | I>T | No | EVA | |
| rs3388594569 | 552 | E>D | No | EVA |
No associated diseases with Q8BKU8
No regional properties for Q8BKU8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q8BKU8 | |||
5 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| Golgi apparatus | A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways. |
| Golgi membrane | The lipid bilayer surrounding any of the compartments of the Golgi apparatus. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| membrane | A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| retrograde transport, endosome to Golgi | The directed movement of membrane-bounded vesicles from endosomes back to the trans-Golgi network where they are recycled for further rounds of transport. |
5 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q8NBN3 | TMEM87A | Transmembrane protein 87A | Homo sapiens (Human) | PR |
| Q96K49 | TMEM87B | Transmembrane protein 87B | Homo sapiens (Human) | PR |
| Q8BXN9 | Tmem87a | Transmembrane protein 87A | Mus musculus (Mouse) | PR |
| Q91WD0 | Gpr108 | Protein GPR108 | Mus musculus (Mouse) | PR |
| Q28EW0 | tmem87a | Transmembrane protein 87A | Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAAACRSEAG | LLPSLLCRRP | AGAQLLRVAL | CLLCWVPAAV | DAVPELGLWT | RTVNDKSGPL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VFRKTMFNST | EIKFSVKSFS | CSGPVKFTIE | WHLKYHTCHN | DYPDLEEELS | QRHELHADPD |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VCAYFKNIDC | WTTKSENLDC | SSDSQAFPSL | NNKELTGIRN | ISSQEGSTDV | VARTQKDGFH |
| 190 | 200 | 210 | 220 | 230 | 240 |
| IFIVSIKTEK | TDAVWDLNVS | LSMVGPHGYI | SASDWPLMIF | YMVMCIVYIL | YGVLWLLWSA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| CYWKDILRIQ | FWIAAVIFLG | MLEKAVFYSE | YQNINSTGLS | TQGLLIFAEL | ISAVKRTLAR |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LLVIIVSLGY | GIVKPRLGTV | MHRVIGLGLL | YLIFAAIEGV | MRVIGGSKHL | AVVLTDIVLA |
| 370 | 380 | 390 | 400 | 410 | 420 |
| VIDSIFVWFI | FISLAQTMKT | LRLRKNTVKF | SLYRHFTNTL | IFAVLASIVF | MVWTTKTFRI |
| 430 | 440 | 450 | 460 | 470 | 480 |
| AKCQSDWMEL | WVDDAFWSFL | FSVILIVIMF | LWRPSANNQR | YAFMPLIDDS | DDEVEEFMVT |
| 490 | 500 | 510 | 520 | 530 | 540 |
| SENLTEGIKL | RASKTVSNGT | AKPTSDNFDE | DLKWVEENIP | SSFTDVALPV | LVDSDEEIMT |
| 550 | |||||
| RSEIAEKMFS | SEKIM |